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Ness Awarded $2.2 Million Grant

University of New Mexico Comprehensive Cancer Center Scott Ness, PhD, received $2.2 million in renewed funding from the National Institute of Dental and Craniofacial Research for his grant, "Mutations and Target Genes in Adenoid Cystic Carcinoma." Dr. Ness and UNM Comprehensive Cancer Center colleagues David Y. Lee, MD, PhD, and Huining Kang, PhD, will investigate functions of MYB oncogenes in salivary gland tumors and develop a clinical test to identify patients with Adenoid Cystic Carc…
Castro Inducted Into 2023 Class of AIMBE College of Fellows

Castro Inducted Into 2023 Class of AIMBE College of Fellows

University of Michigan Rogel Cancer Center Maria G. Castro, PhD, R.C. Schneider Collegiate Professor of Neurosurgery and professor of cell and developmental biology at the University of Michigan, was inducted to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. Read More

Sex, Age, Mental Health and More Can Affect Perceived Barriers to Genetic Testing for Cancer

University of Michigan Rogel Cancer Center Genetic testing barriers for patients with cancer may vary based on demographics and other personal factors, a pilot project linked with a large clinical trial found. In a University of Michigan study, women, for instance, were more likely to report worries about the implications of their test results for family members and how the results could affect their health and life insurance. Read More

Novel Immunotherapy Delivery Approach Safe and Beneficial for Some Melanoma Patients With Leptomeningeal Disease

The University of Texas MD Anderson Cancer Center A novel approach to administer intrathecal immunotherapy (directly into the spinal fluid) and intravenous immunotherapy was safe and improved survival in a subset of patients with leptomeningeal disease from metastatic melanoma, according to interim analyses of a Phase I/Ib trial led by researchers at The University of Texas MD Anderson Cancer Center. Read More
New Leaders to Oversee Key Areas

New Leaders to Oversee Key Areas

Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center announces the promotion and appointment of three leaders: Ericka Bennett, Esq., has been promoted to vice president of corporate ethics, research integrity and research subject protection; Petrina Hill-Cheatom, MEd, is chief academic officer and vice president for educational affairs; and Anthony Putrelo, PE, has been named vice president of facilities management. Read More
U Chicago Led Team Selected for Challenge Award

UChicago-Led Team Selected for Challenge Award

The University of Chicago Medicine Comprehensive Cancer Center The Prostate Cancer Foundation has awarded a $1 million grant to Akash Patnaik, MD, PhD, MMSc, and his team at UChicago Medicine Comprehensive Cancer Center. They will head a multi-institutional group to investigate whether activation of NLRP3 will sensitize advanced prostate cancer to immune checkpoint immunotherapy. Read More
Secord Installed as New President of SGO

Secord Installed as New President of SGO

Duke Cancer Institute, Duke University Medical Center Angeles Alvarez Secord, MD, MHSc, associate director of clinical research in Duke Cancer Institute's Gynecologic Cancer Disease Group, was officially installed as president of the Society of Gynecologic Oncology in March. Read More
Rathmell Elected to American Academy of Arts Sciences

Rathmell Elected to American Academy of Arts & Sciences

Vanderbilt-Ingram Cancer Center Kimryn Rathmell, MD, PhD, MMHC, chair of the Department of Medicine at Vanderbilt University Medical Center, is one of four Vanderbilt University faculty members elected this year to the American Academy of Arts & Sciences. Dr. Rathmell is internationally recognized for her molecular biology research in the pathogenesis of kidney cancer. Read More
Ganz Receives AACR American Cancer Society Award

Ganz Receives AACR-American Cancer Society Award

UCLA Jonsson Comprehensive Cancer Center Patricia A. Ganz, MD, has been awarded the 2023 AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention. The award recognizes outstanding research accomplishments in cancer epidemiology, biomarkers, and prevention. Read More
Ford Invited to Join Advisory Board

Ford Invited to Join Advisory Board

Hollings Cancer Center, Medical University of South Carolina Marvella Ford, PhD, was invited to join the National Minority Quality Forum's Cancer Stage Shifting Initiative's Scientific Advisory Board. The forum is a 501(c)3 nonprofit research and educational organization dedicated to ensuring high-risk racial and ethnic populations and communities receive optimal health care. Read More

Researchers Identify Promising New Target for Treatment-Resistant Prostate Cancer

UK Markey Cancer Center UK Markey Cancer Center researchers identified a protein that plays an important role in prostate cancer progression as well as resistance to enzalutamide, a common prostate cancer treatment. Read More

Researchers Discover and Target an Unexpected 'Achilles Heel' in Triple-Negative Breast Cancer

Sidney Kimmel Cancer Center at Jefferson Health Researchers at Jefferson Health's Sidney Kimmel Cancer Center have developed a novel therapeutic strategy that could revolutionize treatment of triple-negative breast cancer – and are challenging scientific beliefs in the process. Read More

Research Suggests Novel Therapies to Block Cancer Metastasis Are on the Horizon

The University of Arizona Cancer Center An article published by University of Arizona Cancer Center researchers suggests that there may be new ways to inhibit the spread of prostate cancer. The study presents evidence that a pro-survival protein called PIM1 helps cancer cells move out of the primary site, a process known as metastasis that is responsible for the majority of cancer deaths. Read More
Assistant Director of Diversity Appointed

Assistant Director of Diversity Appointed

The University of Arizona Cancer Center Kelly Palmer, PhD, MHS, CCRP, has been appointed assistant director of Inclusivity, Diversity, Equity and Accessibility for the University of Arizona Cancer Center (UACC). In reference to establishing an office of Diversity, Equity and Inclusion, UACC Director Joann Sweasy, PhD, said that diversity is the number one priority for the cancer center. Read More
Sicklick Appointed Co Leader of Structural and Functional Genomics Program

Sicklick Appointed Co-Leader of Structural and Functional Genomics Program

UC San Diego Moores Cancer Center Jason Sicklick, MD, FACS, has been appointed as the new co-leader of the UC San Diego Moores Cancer Center Structural and Functional Genomics Research Program, joining current co-leader, Jill Mesirov, PhD at the helm of the program. Read More

Study: Lasting Effects of the COVID-19 Pandemic on Cancer Care Confirmed

Duke Cancer Institute, Duke University Medical Center Cancer patients said the COVID-19 pandemic heightened infection concerns, increased feelings of fear, and disrupted their care, according to a research questionnaire. The findings were an update of a previous analysis by researchers at Duke University and The University of Sydney detailing the impacts of living with cancer during the pandemic. Read More
Call For Research Grant and Fellowship Proposals

Call For Research Grant and Fellowship Proposals

The goal of the Prevent Cancer Foundation research program is to identify and fund innovative projects with the potential to make substantial contributions to cancer prevention or early detection. Learn more and apply for a $100,000 award by 11:59 pm eastern time on July 11, 2023. Read about awarded researchers and the impact of the research program and use our Award Database to discover previously funded researchers. Visit Our Website
Study of Cancer Metastasis Gets 35 Million Boost

Study of Cancer Metastasis Gets $35 Million Boost

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University With a $35 million gift from researcher, philanthropist, and race car driver Theodore Giovanis, scientists at Johns Hopkins Medicine will study the biological roots of how cancer spreads through the body. The 15-year commitment will establish the Giovanis Institute for Translational Cell Biology. Andrew J. Ewald, PhD, is the institute's new director. Read More
VCU Massey Cancer Center Achieves NCI Comprehensive Status

VCU Massey Cancer Center Achieves NCI Comprehensive Status

VCU Massey Cancer Center has been designated a Comprehensive Cancer Center by the National Cancer Institute (NCI). Massey’s receipt of the highest level of recognition from the NCI places it among an elite group of cancer centers influencing a new standard of care through research, education, and community engagement. Massey’s director, Robert A. Winn, MD, is the first African American to lead a cancer center to comprehensive status. Dr. Winn is AACI's vice president/president-elect. Read More
Effects of Menthol E Cigarette Flavors Considered for People Who Currently Smoke Cigarettes

Effects of Menthol, E-Cigarette Flavors Considered for People Who Currently Smoke Cigarettes

Hollings Cancer Center, Medical University of South Carolina As the U.S. Food and Drug Administration (FDA) wrestles with the best way to regulate a legal but deadly product, it turns to scientists with expertise in tobacco control. As part of that effort, the FDA’s Center for Tobacco Products recently awarded Tracy Smith, PhD, two grants totaling $7.5 million to study the likely effects of allowing flavored e-cigarettes and a ban on menthol. Read More
Ashworth Honored for Research Contributions

Ashworth Honored for Research Contributions

UCSF Helen Diller Family Comprehensive Cancer Center Alan Ashworth, PhD, FRS, president of the UCSF Helen Diller Family Comprehensive Cancer Center, has been recognized for his transformative contributions to cancer research. The American Society of Clinical Oncology honored him with the 2023 Science of Oncology Award and Lecture, and Memorial Sloan Kettering Cancer Center named him for its C. Chester Stock Award Lectureship. Read More
Leaders Honored as ASCO Advocacy Champions

Leaders Honored as ASCO Advocacy Champions

University of Florida Health Cancer Center Thomas George, MD, FACP, and Merry Jennifer Markham, MD, FACP, FASCO, have been honored by the American Society for Clinical Oncology as Advocacy Champions for exemplifying cancer care advocacy in 2022. Dr. George is chair-elect of AACI's Clinical Research Innovation (CRI) Steering Committee. Read More
Winship Opens New Cancer Care Center in Midtown Atlanta

Winship Opens New Cancer Care Center in Midtown Atlanta

Winship Cancer Institute of Emory University The new Winship Cancer Institute at Emory Midtown opened for patients May 9. Winship Cancer Institute designed the full-service center to support a unique model of patient-centered, multidisciplinary cancer care integrated with innovative research to provide the best patient outcomes and a personalized patient experience. Read More

Long Telomeres Not 'Fountain of Youth' as Once Thought

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University In a study of 17 people from five families, Johns Hopkins Medicine researchers say they found that ultra-lengthy DNA endcaps called telomeres fail to provide the longevity presumed for such people. Instead, people with long telomeres tend to develop a range of benign and cancerous tumors, as well as the age-related blood condition clonal hematopoiesis. Read More
Berchuck Plichta Named Cancer Genetics Co Directors

Berchuck, Plichta Named Cancer Genetics Co-Directors

Duke Cancer Institute, Duke University Medical Center Duke Cancer Institute faculty Andrew Berchuck, MD, and Jennifer Plichta, MD, MS, were recently named co-directors of cancer genetics at Duke Cancer Institute. Dr. Berchuck is chief of the Division of Gynecologic Oncology and Dr. Plichta is director of the Duke Breast Risk Assessment Clinic. Read More

$3 Million Gift Funds Director of Cancer Research

The University of Arizona The University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies (CAMI)—a national biomedical research hub that will develop novel strategies for the diagnosis, prevention, and treatment of diseases—has received a $3 million gift from Bruce and Patricia Bartlett. The gift creates the George A. Vanderheiden Endowed Chair in Cancer Immunological Research at CAMI. The person who holds the chair will lead the center's cancer divisi…
Clinical Research Innovation Keynote The Power of Positivity

Clinical Research Innovation Keynote: The Power of Positivity

Ted A. James, MD, MHCM, FACS, will present "The Power of Positivity: Building a Stronger, More Resilient Clinical Cancer Research Team" at 3:45 pm central time on Tuesday, June 27, during the 15th Annual AACI Clinical Research Innovation (CRI) Meeting in Rosemont, IL. During this keynote, participants will gain valuable insights and learn actionable tactics for promoting a positive workplace culture, raising morale and retention, and improving outcomes.  Read More

A Metabolic Process in Cancer Cells Could Unlock a Possible Treatment for Glioblastoma

UCLA Jonsson Comprehensive Cancer Center A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that targeting a metabolic process in people with a specific genetic mutation could help treat glioblastoma. The genetic alteration—a deletion in a gene called CDKN2A—is present in about 60 percent of people with glioblastoma. The mutation causes changes in the way lipids are distributed in cancer cells, which in turn makes the cancer cells vulnerable to being des…

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Public Policy

AACI coordinates efforts among cancer centers to advocate for public policy that benefits patients and to educate legislators on the value of cancer research funding. 
Annual Meeting Keynote NC Is Division of Cancer Prevention

Annual Meeting Keynote: NCI's Division of Cancer Prevention

Philip E. Castle, PhD, MPH, will present "From Global Interventions to Individual Effort: NCI's Division of Cancer Prevention," during the 2023 AACI/CCAF Annual Meeting in Washington DC. Dr. Castle, director of the Division of Cancer Prevention (DCP) at the National Cancer Institute (NCI), will provide an update on DCP/NCI initiatives to support research on novel interventions for cancer prevention, cancer screening, and symptom management. The keynote begins at 1:45 pm eastern time, Sunday, Oc…

Study Shows Immigrant Adults With Liver Cancer Have Higher Survival Rates Than Those Born in the U.S.

USC Norris Comprehensive Cancer Center Immigrant adults with liver cancer in the United States have higher survival rates than people with the disease who were born in the U.S., according to new research from the USC Norris Comprehensive Cancer Center. The study identified a previously unrecognized disparity in survival after a diagnosis of liver cancer across all major racial/ethnic groups, with immigrants having better survival compared to those born in the U.S. Read More

Gene p16 Drives Colorectal Cancer, Emerging as Target for Potential Therapies

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models. The researchers also revealed a strategy that reduced tumor growth and improved survival in tumor-bearing mice, opening new possibilities for future targeted therapies…
New Onco Biobank Director Appointed

New OncoBiobank Director Appointed

Cedars-Sinai Cancer Cedars-Sinai Cancer welcomes Karine Sargsyan, MD, formerly director of one of the world’s largest clinical biobanks, as scientific director of its OncoBiobank. Dr. Sargsyan is charged with leading biobank development and creating new strategies for the optimal deployment and use of the Cedars-Sinai Cancer Molecular Twin Precision Oncology Platform for both research and clinical practice. Read More
Cancer Research Advocates Return to Capitol Hill

Cancer Research Advocates Return to Capitol Hill

On Thursday, May 18, AACI co-hosted the 2023 Hill Day with the American Association for Cancer Research (AACR) – the first in person since 2019. Eighty-five participants, including cancer center directors, researchers, oncologists, survivors, and other advocates, representing 27 states, attended meetings with legislators and staff on Capitol Hill. The group gathered to present a unified voice in support of stable funding increases for the National Institutes of Health (NIH) and the National Can…

Rethinking the Protein Inhibitor Approach to Cancer Therapy

Stony Brook Cancer Center A new method that enables researchers to dial up or tone down the amount of a certain metastatic protein inhibitor (BACH1) within a cell could provide a new path in cancer research that reassesses the effectiveness of protein inhibitors to treat disease. Led by a team of Stony Brook University scientists, the research involves adjusting the levels of BACH1 using a gene circuit placed into human breast metastatic cells. Read More

Researchers Get $3 Million to Improve Survivorship Care for Younger Colorectal Cancer Patients

University of Michigan Rogel Cancer Center A team of University of Michigan Rogel Cancer Center researchers have received a $3.07 million grant from the National Cancer Institute to develop a model for long-term surveillance and care of younger adults treated for colorectal cancer. Read More
Major Expansion Provides Improved Cancer Care to Utah and Beyond

Major Expansion Provides Improved Cancer Care to Utah and Beyond

Huntsman Cancer Institute at the University of Utah Huntsman Cancer Institute has announced the opening of the Kathryn F. Kirk Center for Comprehensive Cancer Care and Women’s Cancers. The center has an entire floor dedicated to breast and gynecologic cancers and additional space for the sophisticated treatment of blood and marrow transplant patients, including immunotherapies and clinical trial options. Read More
Wetter Named Inaugural Senior Director of Cancer Health Equity Science

Wetter Named Inaugural Senior Director of Cancer Health Equity Science

Huntsman Cancer Institute at the University of Utah David W. Wetter, PhD, has been appointed inaugural senior director of cancer health equity science at Huntsman Cancer Institute. Dr. Wetter also serves as the director of the Center for Health Outcomes and Population Equity. Read More
Foucar Joins UNM

Foucar Joins UNM

University of New Mexico Comprehensive Cancer Center Charles Foucar, MD, applies his problem-solving experiences in engineering and computer sciences to his work as a hematologist-oncologist at the UNM Comprehensive Cancer Center. Dr. Foucar holds a medical degree from Northwestern University and his research interests are in high-risk leukemias that can occur after treatment for other medical conditions or cancers. Read More

Allison Institute Announces Appointment of Inaugural Members

The University of Texas MD Anderson Cancer Center The James P. Allison Institute at The University of Texas MD Anderson Cancer Center announced the appointment of its first members, James P. Allison, PhD; Padmanee Sharma, MD, PhD; Jennifer Wargo, MD; Sangeeta Goswami, MD, PhD; and Kenneth Hu, PhD. In addition, Garry Nolan, PhD, will join the Allison Institute as an adjunct member. The institute was launched to drive breakthroughs that will integrate immunobiology across disciplines. …

Study Highlights Racial Disparities in Ovarian Cancer Risk for Women

Fred Hutchinson Cancer Center A new Fred Hutchinson Cancer Center study investigated how endometriosis, uterine leiomyomas (fibroids), and hysterectomy changed ovarian cancer risk in Black and white women. Fibroids were associated with an increased risk of ovarian cancer in both Black and white women, with hysterectomy modifying the risk of cancer in both groups. However, scientists also found that while Black and white women with endometriosis had a higher risk of ovarian cancer overall…

Healthy Lifestyle Reduces Risk of Recurrence and Death in High-Risk Breast Cancer Patients

Roswell Park Comprehensive Cancer Center High-risk breast cancer patients who most closely followed cancer-prevention guidelines published by the American Institute for Cancer Research and American Cancer Society before, during, and after chemotherapy experienced a 37 percent reduced risk of disease recurrence and a 58 percent reduced risk of death, according to a study led by Roswell Park Comprehensive Cancer Center. Read More

A Simple Antibacterial Treatment Solves a Severe Skin Problem Caused by Radiation Therapy

Montefiore Einstein Comprehensive Cancer Center Researchers at the Montefiore Einstein Cancer Center have found that many cases of acute radiation dermatitis involve a common skin bacterium and that a simple, low-cost treatment can prevent severe cases, potentially setting a new standard of care for people undergoing radiation therapy. Read More
Allen Named DUHS Vice President for Cancer Services

Allen Named DUHS Vice President for Cancer Services

Duke Cancer Institute, Duke University Medical Center Peter J. Allen, MD, has been named Duke University Health System vice president for cancer services. He will oversee clinical cancer care for Duke, working closely with Duke Cancer Institute Executive Director Michael Kastan, MD, PhD. Dr. Allen currently serves as the chief of the Division of Surgical Oncology. His research lab focuses on pancreatic cancer. Read More
Mao Awarded 1 6 Million Grant

Mao Awarded $1.6 Million Grant

University of New Mexico Comprehensive Cancer Center Peng Mao, PhD, at the UNM Comprehensive Cancer Center, was awarded a National Cancer Institute grant totaling $1.6 million over five years for research into the "Mechanism of Transcription-coupled DNA Repair and its Impact on Cancer Mutations." Dr. Mao's research will focus on how the RNA polymerase complex recruits other molecules to repair DNA during transcription. Read More
Vitalief Cultivating the Clinical Trial Office and Beyond

Vitalief: Cultivating the Clinical Trial Office and Beyond

Vitalief is a Functional Service Provider (FSP) offering robust solutions that help research organizations and clinical trial offices address the Healthcare Human Capital Epidemic. Consulting Resourcing & Education  Managed Services Visit us at the 15th Annual AACI CRI Meeting!   Learn More

Study Identifies New Treatment Target for Metastatic Cancer

UK Markey Cancer Center A new UK Markey Cancer Center study reveals more about changes that happen to cancer cells when they metastasize and identifies a promising target for the treatment of metastatic breast cancer. The research shows a metabolite called succinate plays a role in enhancing cancer cell plasticity and identifies an enzyme called PLOD2 as a regulator of succinate during breast cancer progression. Read More

Study Finds Cancer Cells Use a New Fuel in Absence of Sugar

University of Michigan Rogel Cancer Center Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings show that cancer cells can adapt when they don’t have access to glucose. Read More

Scientists Create Most Powerful, Accurate Tool Yet to Research Deadliest Blood Cancer

The Tisch Cancer Institute at Mount Sinai Tisch Cancer Center scientists have developed unique models of acute myeloid leukemia, creating a transformative resource to study this cancer and eventually its drug response and drug resistance. The researchers said these models represent the disease accurately in genetic composition and in disease characteristics found in laboratory cell cultures, animal models, and patients. Read More

Microbiome Varies Widely in Tumors of People With Early Vs. Late-Onset Colorectal Cancer

Georgetown Lombardi Comprehensive Cancer Center Researchers at Georgetown Lombardi Comprehensive Cancer Center studied the microbiome of people with colorectal cancer and found the makeup of the bacteria, fungi, and viruses in a person’s tumor varied significantly depending on whether they were diagnosed with early onset disease (age 45 or younger) or late-onset disease (age 65 or older). Read More
Senior Director of Community Outreach and Engagement Named

Senior Director of Community Outreach and Engagement Named

Huntsman Cancer Institute at the University of Utah Rachel Ceballos, PhD, has been appointed senior director of community outreach and engagement at Huntsman Cancer Institute, associate professor in the Department of Family and Preventive Medicine, and a Huntsman Cancer Institute Endowed Chair in Cancer Research. Read More

State Legislators Thanked for Securing $1.5 Million in Funding

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center and Temple Health welcomed State Representative Kevin Boyle and State Senators Jimmy Dillon and Christine Tartaglione to the Fox Chase campus to thank them for their support in securing $1.5 million in funding for the modernization of Fox Chase research facilities. Read More

Excess and Rising Weight in Adulthood Associated With Increased Risk of Gastrointestinal Cancer

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Doctors have long stressed the importance of maintaining a healthy weight for improving overall health, but a large new study suggests it could also reduce future gastrointestinal cancer risk. The study found that an overweight or obese body mass index in early and middle adulthood is associated with increased risk for gastrointestinal cancer. The study also found that frequent asp…

Ascending the 'Mount Everest' of Cancer Research

University of Florida Health Cancer Center The cancer gene MYC has been called the "Mount Everest" of cancer research because of the difficulty of designing medications that can disable it, and the expectation that an effective MYC drug could help so many cancer patients. A collaboration among RNA scientists, chemists, and cancer biologists in Florida and Germany has climbed that peak, while opening new routes to summit other similarly hard-to-treat diseases. Read More
Mc Kenna is New Chief Human Resources Officer

McKenna is New Chief Human Resources Officer

Moffitt Cancer Center Jack McKenna has joined Moffitt Cancer Center as the new chief human resources (HR) officer. In his role, he will lead the cancer center’s HR team and oversee HR strategies and functions. McKenna has nearly 40 years of experience in human resources and organizational development, most recently serving as chief human resources officer at Universal Engineering Sciences, Inc., a national geotechnical engineering firm. Read More
Howe Appointed Associate Director of Cancer Research Training and Education

Howe Appointed Associate Director of Cancer Research, Training, and Education

The University of Vermont Cancer Center Alan Howe, PhD, associate professor of pharmacology, has been appointed to serve as associate director of cancer research, training and education coordination for the University of Vermont Cancer Center. Dr. Howe has been a member of UVM’s Cell, Molecular, and Biomedical Sciences Graduate Program for nearly 20 years. Read More
Skalka Receives Reimann Honor Award

Skalka Receives Reimann Honor Award

Fox Chase Cancer Center, Temple Health In a ceremony honoring faculty at Fox Chase Cancer Center, Anna Marie Skalka, PhD, senior advisor to the president and professor emerita, was recognized with the Stanley P. Reimann Honor Award, the center’s highest distinction. Read More

Scientists Discover Hidden Weakness in Deadly Brain Cancer

UCSF Helen Diller Family Comprehensive Cancer Center Scientists at UC San Francisco have discovered that neural activity in difficult-to-treat glioblastoma can restructure connections in surrounding brain tissue, causing the cognitive decline associated with the disease, and that the drug gabapentin, commonly used to prevent seizures, could block this growth-causing activity in mice with glioblastoma. Read More

Potential New Strategy Identified to Prevent Side Effects From Immunotherapy

UCLA Jonsson Comprehensive Cancer Center A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that IL-21, a soluble molecule involved in activating the immune system, can be a potential therapeutic target to help reduce endocrine autoimmune side effects caused by checkpoint inhibitor cancer therapy. Read More

Delivering on the Promise of Personalized Breast Cancer Therapy

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine A team led by researchers at Baylor College of Medicine is coming closer to delivering on the promise of personalized breast cancer therapy with a strategy to predict the most likely response of a cancer to a specific less toxic treatment regimen. In this study, the scientists developed and validated in clinical trials a multiparameter molecular classifier test to predict with a high degree of confidence which patient…

Combined Delivery of Engineered Virus With Immunotherapy is Safe and Improves Outcomes in Subset of Patients With Glioblastoma

The University of Texas MD Anderson Cancer Center Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto. Read More
HHMI Selects Byndloss as Early Career Scholar

HHMI Selects Byndloss as Early-Career Scholar

Vanderbilt-Ingram Cancer Center The Howard Hughes Medical Institute (HHMI) has selected Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology at Vanderbilt University Medical Center, as one of its first Freeman Hrabowski Scholars. Dr. Byndloss is co-director of the Vanderbilt Microbiome Innovation Center. Read More

Risk Biomarkers Could Predict Serious Side Effect of Stem Cell Transplant

Hollings Cancer Center, Medical University of South Carolina Doctors are one step closer to having a risk biomarker to alert them to which of their pediatric stem cell transplant patients are likely to experience a potentially deadly side effect called sinusoidal obstruction syndrome. A team led by MUSC Hollings Cancer Center researcher Sophie Paczesny, MD, PhD, recently published the results of its biomarker study. Read More

Genomic Analysis of SCLC Tumors Reveals Subtypes, Offers Cues Toward Personalized Treatments

Vanderbilt-Ingram Cancer Center The largest genomic analysis ever conducted of small cell lung cancer (SLSC) tumors has identified genetic subtypes and provided insights into the mechanisms of this aggressive and deadly cancer. The study reveals cues toward the development of personalized treatment approaches. Read More

CAR T Cells Developed That Fight Prostate Cancer in Bone

Moffitt Cancer Center Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients. In a new article, a team of Moffitt scientists demonstrates that chimeric antigen receptor T-cell (CAR T) therapy is an effective antitumor approach in mouse models of bone metastatic prostate cancer. Read More

Winship Catalyst Fund Bridges Research Funding Gap

Winship Cancer Institute of Emory University Atlantan Bernard "Berny" Gray has created a unique endowment at Winship Cancer Institute that addresses an underfunded stage of the research pipeline. The Winship Catalyst Fund will enable Winship researchers to bring promising drugs and treatment strategies from discovery to clinical use. Read More
Loss of Y Chromosome in Men Enables Cancer to Grow

Loss of Y Chromosome in Men Enables Cancer to Grow

Cedars-Sinai Cancer As men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body’s ability to fight cancer, according to new research from Cedars-Sinai Cancer. Dan Theodorescu, MD, PhD, director of Cedars-Sinai Cancer, is corresponding author of the study published in the journal Nature. Read More
Winship Renewed as NCI Designated Comprehensive Cancer Center

Winship Renewed as NCI-Designated Comprehensive Cancer Center

Winship Cancer Institute of Emory University Winship Cancer Institute has received renewal of the prestigious Comprehensive Cancer Center designation from the National Cancer Institute (NCI), ensuring its continuing place in the top tier of U.S. cancer centers. Winship first earned NCI designation in 2009 and achieved comprehensive status in 2017. Suresh S. Ramalingam, MD, FACP, FASCO, is the center's executive director. Read More
100 Million Lead Gift to Support Transformative New Cancer Research and Care Facility

$100 Million Lead Gift to Support Transformative New Cancer Research and Care Facility

The University of Kansas Cancer Center The Sunderland Foundation has given The University of Kansas Cancer Center a $100 million lead gift to build a new, state-of-the-art destination cancer center. This transformative gift is both the largest gift ever given by the Sunderland Foundation and the largest ever received by the University of Kansas and The University of Kansas Health System. Read More
Radiation Oncologist William Blackstock Dies

Radiation Oncologist William Blackstock Dies

Atrium Health Wake Forest Baptist Comprehensive Cancer Center A. William Blackstock Jr., MD, FASCO, chair of the Department of Radiation Oncology at Atrium Health Wake Forest Baptist, passed away in June at age 60 due to complications from prostate cancer. He was one of the first African American chairs in the field and began his career at UNC Lineberger Comprehensive Cancer Center. Read More
50 Million State Investment to Fund Expansion of Research and Treatments

$50 Million State Investment to Fund Expansion of Research and Treatments

WVU Cancer Institute West Virginia University’s efforts to reimagine and expand cancer care received a $50 million boost as Governor Jim Justice joined WVU academic and health system leaders to announce state surplus funding that will support investment to attain National Cancer Institute designation. Hannah Hazard-Jenkins, MD, FACS, is director of the WVU Cancer Institute. Read More
Huntsman Plans for New Comprehensive Cancer Center

Huntsman Plans for New Comprehensive Cancer Center

Huntsman Cancer Institute at the University of Utah Huntsman Cancer Institute at the University of Utah has announced plans for a new Huntsman Cancer Institute comprehensive cancer center in Utah County. This second headquarters will be in Vineyard, a growing city embedded in Utah’s tech hub. Read More

Study Identifies Marked Disparities in Federal Cancer Research Funding

Sylvester Comprehensive Cancer Center, University of Miami A research team at Sylvester Comprehensive Cancer Center compiled and analyzed statistics from federal cancer research funding sources and found that funds tend to be allocated more heavily toward cancers that occur more often in non-Hispanic white people than in other racial and ethnic groups. Read More

Project Stella Enables Novel Pediatric AML Immunotherapies, Potential Cure

Fred Hutchinson Cancer Center Soheil Meshinchi, MD, PhD, a Fred Hutch pediatric hematologist/oncologist, studies a rare subtype of pediatric acute myeloid leukemia. His work is supported by Project Stella, a philanthropic initiative to raise funding for development of a new immunotherapy to treat this cancer. Dr. Meshinchi’s work has resulted in several potential drugs against this cancer, as well as the development of immunotherapy treatment. Read More
Cairns Elected Fellow of the Royal Society

Cairns Elected Fellow of the Royal Society

Huntsman Cancer Institute at the University of Utah The Royal Society, the world’s oldest science academy, has elected Bradley R. Cairns, PhD, to the Fellows of the Royal Society. Dr. Cairns serves as the chief academic officer of Huntsman Cancer Institute, Jon M. Huntsman Presidential Endowed Chair in Cancer Research, and investigator with Howard Hughes Medical Institute and Huntsman Cancer Institute. Read More
UF Health Cancer Center Achieves NCI Designation

UF Health Cancer Center Achieves NCI Designation

The University of Florida Health Cancer Center has joined the ranks of the country’s most distinguished cancer centers as the 72nd National Cancer Institute (NCI)-Designated Cancer Center in the United States. Led by Jonathan D. Licht, MD, the center doubled its peer-reviewed cancer research funding since 2016, with $48.8 million in total cancer research grants and 359 active cancer research projects last year. Read More

Emerging Leaders Sought to Join EAB

The University of Vermont Cancer Center The University of Vermont Cancer Center seeks early career faculty to participate in its external advisory board. The deadline to apply is September 1. This opportunity is designed for future leaders who represent groups underrepresented in biomedical science and in cancer center leadership positions across the country. Read More
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Study Discovers That Tumor Mutation Burden Predicts Survival Outcome

Vanderbilt-Ingram Cancer Center The expected course of a patient’s cancer prognosis has traditionally been judged by its type, stage, and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence. Read More

Breast Density and BMI Both Play a Role in Breast Cancer Risk

UCSF Helen Diller Family Comprehensive Cancer Center Breast density shouldn’t be the only factor in determining whether supplemental screening is warranted, reported researchers in a large new study led by UC San Francisco and UC Davis. Lead author Karla Kerlikowske, MD, noted that incorporating breast density and BMI would better identify women with high breast density at risk of a missed or advanced cancer rather than using breast density alone. Read More

KU Cancer Center Joins ORIEN

The University of Kansas Cancer Center The University of Kansas (KU) Cancer Center has joined the Oncology Research Information Exchange Network (ORIEN), a national initiative promoting collaboration to drive research and discovery of personalized treatments for cancer. Launched in 2014 and comprised of 18 cancer centers across the U.S., it is the largest and longest-running academic cancer research consortium of its kind in the United States. Read More

Study Reveals How Treatment-Resistant Prostate Cancer Provides Its Own Hormonal Fuel

Siteman Cancer Center A new study from Siteman Cancer Center discovered that when prostate cancer cells are treated with testosterone-blocking medication, they end up producing more cholesterol to generate their own testosterone. The study reveals a possible drug combination that could stop the cancer from feeding its own growth. Read More

Smart Drugs Give New Hope to Some Patients With Advanced Pancreatic Cancer

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home. The treatment will be available through a first-of-its-kind, entirely telehealth-based cancer clinical trial at The Ohio State University Comprehensive Cancer Center. Read More

Liquid Biopsy Predicts Early Disease Progression, Potential Survival in Patients With Advanced Breast Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can be used to predict early disease progression and potential survival among patients with metastatic breast cancer in as little as one month after starting treatment, according to a recent study. Read More
Advani Appointed Co Leader of Cancer Biology and Signaling Program

Advani Appointed Co-Leader of Cancer Biology and Signaling Program

UC San Diego Moores Cancer Center As the new co-leader of the Moores Cancer Center cancer biology and signaling research program, Sunil J. Advani, MD, will join current co-leader, Jing Yang, PhD at the helm of the program. Dr. Advani studies the tumor-targeted delivery of anti-cancer agents in combination with radiotherapy for locally aggressive tumors. Read More
Lee Elected American Statistical Association President

Lee Elected American Statistical Association President

University of Florida Health Cancer Center Members of the American Statistical Association have elected Ji-Hyun Lee, DrPH, a professor of biostatistics in the University of Florida College of Public Health and Health Professions and the UF College of Medicine, president of ASA for the 2025 term. Dr. Lee also serves as the director of the Division of Quantitative Sciences at the UF Health Cancer Center. Read More
Survivorship Program Launched for Adolescents and Young Adults

Survivorship Program Launched for Adolescents and Young Adults

University of New Mexico Comprehensive Cancer Center The UNM Comprehensive Cancer Center is launching an adolescent and young adult survivorship program, coordinated by Amy Gundelach, RN, MSN, AG-CNS-BC, OCN. Individualized survivorship care plans encourage communication and collaboration among patients and their cancer treatment and primary care providers. Read More
Program Gives Undergrads Pathway to Cancer Careers

Program Gives Undergrads Pathway to Cancer Careers

University of Michigan Rogel Cancer Center What does it look like to work in cancer research? For two weeks this summer, 20 undergraduate students from public universities across Michigan will find out. The Rogel Cancer Center’s Pathways Undergraduate Fellowship program launched in 2022 to fill a gap in training programs that left out undergraduate students. Read More

Researchers Receive $2 Million to Study Pancreatic Cancer Microenvironment

University of Michigan Rogel Cancer Center Researchers at the University of Michigan Rogel Cancer have received a $2 million grant from the National Cancer Institute to understand the role myeloid cells play in how pancreatic cancer develops and progresses. They will use patient tissue samples and genetically-engineered mouse models to map myeloid cell populations and functional status in the healthy pancreas, pancreatic intraepithelial neoplasia, and pancreatic cancer. Read More

Study Finds Functional Limitations Increasing in Survivors of Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University The percentage of survivors of cancer reporting functional limitations in the United States has more than doubled over the past 20 years, according to a new study. The work was a collaborative effort from investigators at the Johns Hopkins Kimmel Cancer Center, the Dell Medical School in Austin, Texas, and the University of Minnesota’s Masonic Cancer Center in Minneapolis. Read More

Deterministic Evolution and Stringent Selection During Preneoplasia

Stanford Cancer Institute Stanford Cancer Institute members Calvin Kuo, MD, PhD, Christina Curtis, PhD, and colleagues have published an article in Nature that provided valuable insights into the early stages of cancer development and showed that there are predictable patterns and constraints in the process. These findings have implications for detecting cancer at an earlier stage and preventing aggressive tumors. Read More
Sawyer Tapped as Inaugural Chair of Bioengineering

Sawyer Tapped as Inaugural Chair of Bioengineering

Moffitt Cancer Center Moffitt Cancer Center has launched the Department of Bioengineering. The new academic research department will be housed within the Division of Basic Science and led by W. Gregory Sawyer, PhD. Prior to joining Moffitt, Dr. Sawyer was a professor of mechanical engineering at the University of Florida. Read More
Van Brocklin Receives Aebersold Award

VanBrocklin Receives Aebersold Award

UCSF Helen Diller Family Comprehensive Cancer Center The Aebersold Award recognizes outstanding achievement in basic science applied to nuclear medicine. For decades, Henry VanBrocklin, PhD, has led research on the preparation and application of novel radiopharmaceuticals. He received the award on June 25 at the Society of Nuclear Medicine and Molecular Imaging Annual Meeting in Chicago. Read More