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Cancer Research Alliance Recognizes Young Investigator

Cancer Research Alliance Recognizes Young Investigator

The Tisch Cancer Institute at Mount Sinai Marta Luksza, PhD, has received a 2023 Pershing Square Sohn Prize for Young Investigators in Cancer Research. Dr. Luksza and team will use approaches from machine learning and physics to develop a predictive model for immune interactions and tumor evolution under vaccine immunotherapy. On the basis of this model, they will build a protocol for the optimal design of personalized anti-tumor vaccines. Read More

Study Reveals a Trio of Immune Cells Vital in Response to Liver Cancer Immunotherapy

The Tisch Cancer Institute at Mount Sinai Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a trio of immune cells within tumor niches that are associated with immunotherapy response in hepatocellular carcinoma. The findings help explain which patients benefit from immunotherapy and which do not. Read More
Filling the LGBTQIA Void in Cancer Research

Filling the LGBTQIA+ Void in Cancer Research

University of New Mexico Comprehensive Cancer Center When Prajakta Adsul, MBBS, PhD, MPH, at the UNM Comprehensive Cancer Center, learned about LGBTQIA+ communities in New Mexico, she became inspired to start filling the void of information about cancer screening and survivorship in these populations. Using a novel survey, she and her team collected information from 2,500 individuals; it's the largest volume of data of its kind. Read More

AI-Driven Biomarker Predicts Optimum Length of Treatment for Prostate Cancer

Duke Cancer Institute, Duke University Medical Center In an oral presentation at ASCO23, Andrew Armstrong, MD, MSc, reported that an AI-derived digital pathology tool was able to identify which men treated with radiation for high-risk localized prostate cancer could be spared long-term hormone therapy and its potential side effects. Dr. Armstrong is a Duke Cancer Institute genitourinary oncologist. Read More
More Evidence Needed to Confirm Promise of Remote or Decentralized Trials

More Evidence Needed to Confirm Promise of Remote or Decentralized Trials

Hollings Cancer Center, Medical University of South Carolina There’s one question that Jennifer Dahne, PhD, co-director of the remote and virtual trials program at the South Carolina Clinical & Translational Research Institute, hears more than any other: Will remote—or decentralized—clinical trials overcome the barriers that make it difficult for minority and underserved populations to participate in clinical research? Read More

Study May Provide Clues to Treating Colorectal Cancer More Effectively in Younger Patients

Roswell Park Comprehensive Cancer Center A novel study led by medical oncologists at the Gastrointestinal Center at Roswell Park Comprehensive Cancer Center is shedding light on factors that may affect treatment response in younger people with colorectal cancer. That information could guide the development of new treatments for younger patients, who typically have poorer outcomes. Read More

Smoking Treatment Accreditation Earned

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center has been accredited by the Smoking Treatment Accreditation & Recognition (STAR) program, a tobacco treatment initiative funded through a grant from the Pennsylvania Department of Health. STAR seeks to facilitate the integration of tobacco dependence treatment into existing health care workflows in order to elevate the level of treatment available to community members. Read More
Novel Approaches to Help Young Adult Survivors

Novel Approaches to Help Young Adult Survivors

The University of Arizona Cancer Center To assist cancer survivors between the ages of 18–39, Rina Fox, PhD, MPH, University of Arizona Cancer Center member, has spent several years developing an innovative, 10-week eHealth information and peer support stress management program called TOGETHER-YA (Young Adults). Read More

Cancer Cells Rev Up Synthesis, Compared With Neighbors

Siteman Cancer Center Researchers from Siteman Cancer Center have developed a technology to study tumor growth in another dimension, establishing a new method in mouse models of glioblastoma to create a high-resolution map of the tumor ecosystem. The results shed light on how cancer cells in a brain tumor get lipids, which could help scientists slow or stop disease progression. Read More
New Director Joins One Stop Resource for Integrative Cancer Care

New Director Joins One-Stop Resource for Integrative Cancer Care

UCLA Jonsson Comprehensive Cancer Center Shannon La Cava, PsyD, has been named as the new director of the Simms/Mann-UCLA Center for Integrative Oncology, bringing a wealth of experience in meeting the varied emotional needs of people with cancer. Dr. La Cava is an integrative psychologist specializing in psychosocial oncology. Read More
Funchain Joins Stanford

Funchain Joins Stanford

Stanford Cancer Institute The Stanford Cancer Institute welcomes Pauline Funchain, MD. She will join in August as an associate professor of medicine/medical oncology. Dr. Funchain offers additional expertise in cutaneous malignancies, Merkel cell carcinoma, and skin cancer genomics and immunotoxicity. Read More
City of Buffalo First Deputy Mayor Joins Roswell Park as Chief Diversity Officer

City of Buffalo First Deputy Mayor Joins Roswell Park as Chief Diversity Officer

Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center has appointed Crystal Rodriguez-Dabney, Esq., as chief diversity officer and senior vice president. In her leadership role with the City of Buffalo, Rodriguez-Dabney steered successful efforts to engage and support richly diverse communities and organizations. Read More
Le Blanc Named Education Chair Honored for Advocacy

LeBlanc Named Education Chair, Honored for Advocacy

Duke Cancer Institute, Duke University Medical Center Duke Cancer Institute Chief Patient Experience and Safety Officer Thomas LeBlanc, MD, MA, MHS, FAAHPM, FASCO, has been designated chair of the American Society of Clinical Oncology (ASCO) 2024 Annual Meeting Education Program Committee. He was also recently named an ASCO Advocacy Champion, President's Circle for his "active engagement" in ASCO's advocacy activities. Read More

Submit Your Nomination for the AACI Public Service Award

AACI is currently seeking nominations for the 2023 Public Service Award, which will be presented during the 2023 AACI/CCAF Annual Meeting on Monday, October 2, at the Salamander Washington DC. One Republican and one Democrat are eligible to receive the award, which recognizes leaders who demonstrate outstanding support for biomedical research in general, and cancer research in particular, and who support AACI’s mission of enhancing cancer centers and health equity. Read More

Study Finds Women, Underrepresented Groups Experience Higher Rates of Workplace Mistreatment in Academic Medicine

Winship Cancer Institute of Emory University A new study led by Winship Cancer Institute researcher Reshma Jagsi, MD, DPhil, has found that women; racial and ethnic minorities; and individuals identifying as lesbian, gay, bisexual, transgender, and queer are disproportionately affected by workplace mistreatment in academic medicine, and this mistreatment negatively impacts their mental health. Read More

Cancer Experts Warn About Wave of HPV-Related Cancers in Adults

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Experts are concerned about rapidly rising rates of HPV-related throat and mouth cancers, noting that if this trend continues they could quickly be among the most common forms of cancer in adults between the ages of 45 and 65. Read More

Light Endoscope May Enhance Ovarian Cancer Detection and Treatment

Stony Brook Cancer Center A major challenge in the management of advanced ovarian cancer is the detection and treatment of micrometastases within the intraperitoneal cavity. To address this clinical challenge, Ulas Sunar, PhD, has recently been awarded a $1 million grant from the National Cancer Institute. Read More

New Treatment Option for Metastatic Colorectal Cancer Prolongs Survival

Vanderbilt-Ingram Cancer Center A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options. Results from an international clinical trial show that the selective targeted therapy, Fruquintinib, resulted in a statistically significant improvement in overall survival and progression-free survival. Read More

New Drug Delays Glioma Progression

UCLA Jonsson Comprehensive Cancer Center In an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening. The finding suggests a possible new treatment option for people with the slow-growing but deadly brain tumor. Read More
Inaugural Associate Director for Equity Diversity and Inclusion Named

Inaugural Associate Director for Equity, Diversity and Inclusion Named

UC San Diego Moores Cancer Center Melody K. Schiaffino, PhD, MPH, is the new associate director for Equity, Diversity and Inclusion at Moores Cancer Center. She is a health services researcher and epidemiologist who specializes in health disparities as they relate to population health, health services delivery, and quality outcomes. Read More
PCLI Webinar Artificial Intelligence and Its Impact on Cancer Care and Research

PCLI Webinar: Artificial Intelligence and Its Impact on Cancer Care and Research

The AACI Physician Clinical Leadership Initiative (PCLI) will host "Seismic Shift or Small Step Forward? Artificial Intelligence and Its Impact on Cancer Care and Research" at 1:00 pm eastern time on Thursday, July 20. The webinar will describe new advances in artificial intelligence (AI) and machine learning and potential applications for research and discovery. Pictured (L-R): Panelists Christopher Lieu, MD, and Sean Davis, MD, PhD. Read More
Plimack Appointed Treasurer of ASCO

Plimack Appointed Treasurer of ASCO

Fox Chase Cancer Center, Temple Health Elizabeth Plimack, MD, MS, deputy director and professor in the Department of Hematology/Oncology at Fox Chase Cancer Center, has been appointed treasurer of the American Society of Clinical Oncology (ASCO). In 2019, Dr. Plimack was elected to a four-year term on ASCO’s Board of Directors. Read More

Markey Study Reveals Persistent Cancer Disparities in Appalachian Kentucky

UK Markey Cancer Center A recent UK Markey Cancer Center study sheds light on Appalachian Kentucky’s alarming cancer burden, revealing striking disparities compared to non-Appalachian Kentucky and the rest of the country. Kentucky ranks first in the nation for cancer incidence and mortality rates, and Appalachian Kentucky bears the state’s greatest cancer burden. Read More
Avat Joins Moffitt as New Chief Business Officer

Avat Joins Moffitt as New Chief Business Officer

Moffitt Cancer Center Xavier Avat has joined Moffitt Cancer Center as the new chief business officer. He will be responsible for leading the cancer center’s business development strategies and functions. Mr. Avat brings nearly 30 years of experience in marketing, operations, and business development to the role, most recently serving as chief business officer at Capricor Therapeutics, a biotech company. Read More

Grant Moves Breast Cancer Drug Development Work Forward

Hollings Cancer Center, Medical University of South Carolina The National Cancer Institute has awarded LoxiGen, Inc., a startup led by Ozgur Sahin, PhD, a three-year Fast-Track Small Business Technology Transfer (STTR) grant to develop his breast cancer findings. The goal is a drug eligible for Investigational New Drug status from the U.S. Food and Drug Administration. Read More

Comprehensive Cancer Survivorship Act

A bill to address the health of cancer survivors and unmet needs that survivors face through the entire continuum of care from diagnosis through active treatment and posttreatment, in order to improve survivorship, treatment, transition to recovery and beyond, quality of life and palliative care, and long-term health outcomes, including by developing a minimum standard of care for cancer survivorship, irrespective of the type of cancer, a survivor's background, or forthcoming survivorship needs…
15th Annual AACI CRI Meeting Raises Bar for Attendance Abstracts

15th Annual AACI CRI Meeting Raises Bar for Attendance, Abstracts

AACI’s Clinical Research Innovation (CRI) convened its 15th annual meeting June 26-28, in Rosemont, IL. More than 500 colleagues attended in person and 118 abstracts were submitted for presentation – both records for the increasingly popular event focused on clinical trial office operations. Pictured clockwise from top left: Patient advocate Mel Mann; poster session networking; (L-R) panelists Dr. Mark Agulnik, Dr. Shaalan Beg, moderator Angela Fritsche; plenary session attendees. Photo credit…
Integra Connect A Value Based Precision Medicine Company

Integra Connect: A Value-Based, Precision Medicine Company

At Integra Connect, we connect providers, payers, and life sciences with the experiences, outcomes, and costs of cancer they need to understand to improve care, embrace scientific advancements, manage costs, and deliver innovations for patients. Industry-leading specialty care data Insights from powerful AI and analytics solutions Intelligence from unprecedented experience and expertise Watch Our Webinar
AACI Announces 2023 Award Recipients

AACI Announces 2023 Award Recipients

AACI congratulates this year's Distinguished Scientist, Cancer Health Equity, and Champion for Cures award recipients, selected by the AACI Board of Directors. The awards will be presented in person on Monday, October 2, during the 2023 AACI/CCAF Annual Meeting. Pictured, clockwise from top right: Dr. Patricia LoRusso (Distinguished Scientist), Dr. Amelie Ramirez (Cancer Health Equity), and Dana Dornsife, founder and chief mission and strategy officer, Lazarex Cancer Foundation (Champion for C…
Eckhardt Joins Baylor College of Medicine

Eckhardt Joins Baylor College of Medicine

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine S. Gail Eckhardt, MD, FASCO, will join Baylor College of Medicine as associate dean for experimental therapeutics and associate director for translational research at Dan L Duncan Comprehensive Cancer Center in September. Dr. Eckhardt, a former member of AACI's Board of Directors, is the director of the Livestrong Cancer Institutes at the University of Texas. Read More
Comprehensive Cancer Center Designation Renewed

Comprehensive Cancer Center Designation Renewed

University of Michigan Rogel Cancer Center The National Cancer Institute (NCI) has awarded Rogel Cancer Center a $37 million grant over five years, renewing its designation as a comprehensive cancer center. The cancer center first received NCI designation in 1988 and was designated "comprehensive" three years later. The new grant provides funding through 2028, extending Rogel to 40 consecutive years of NCI funding. Eric Fearon, MD, PhD, is center director. Read More
Du Bois Inducted Into Royal College of Physicians

DuBois Inducted Into Royal College of Physicians

Hollings Cancer Center, Medical University of South Carolina MUSC Hollings Cancer Center Director Raymond N. DuBois, MD, PhD, was inducted as a fellow into the Royal College of Physicians, an accolade held by some of the most innovative and inspirational physicians in the world. Dr. DuBois is known for his work illuminating the relationship between inflammation and cancer. Read More
George Crispen Appointed to Executive Leadership Positions

George, Crispen Appointed to Executive Leadership Positions

University of Florida Health Cancer Center The University of Florida Health Cancer Center has appointed two oncologists to key executive leadership roles. Thomas George, MD, FACP, has been named deputy director. He is chair-elect of the AACI Clinical Research Innovation Steering Committee. Paul Crispen, MD, has been named associate director for clinical research. Read More

Study Examines Income Supplementation, Cancer Inequities in Persistent Poverty Areas

Stanford Cancer Institute The National Cancer Institute recently awarded nearly $10 million to a collaboration between Stanford University, the University of California, San Francisco, and UC Davis to launch the UPSTREAM Research Center. The center will investigate whether and in what ways regular income supplementation for people living in poverty in several Northern California communities affect their health behaviors and cancer risk. Read More

Cancer Screening Initiative Launched to Address Racial Disparities

Siteman Cancer Center Siteman Cancer Center launched a prostate cancer screening initiative along with an educational campaign to address the racial disparity in prostate cancer. The campaign aims to spread awareness among African American men in the St. Louis area about their higher risk for prostate cancer (one in six Black men) and why they need to start screening for prostate cancer at ages 40 to 45. Read More

Team Assesses Addition of Complement Inhibitor Drug to Immunotherapy for Ovarian Cancer

Roswell Park Comprehensive Cancer Center Researchers at Roswell Park Comprehensive Cancer Center have launched a Phase II clinical trial that they hope will improve both survival and quality of life for patients with recurrent ovarian, fallopian-tube, or primary peritoneal cancer and malignant effusion. Read More
NCI MERIT Award to Support Colorectal Cancer Research

NCI MERIT Award to Support Colorectal Cancer Research

Vanderbilt-Ingram Cancer Center Andreana Holowatyj, PhD, MSCI, has received the National Cancer Institute’s Method to Extend Research in Time (MERIT) Award to support her ongoing investigation into how early-onset colorectal cancer and its treatments impact reproductive health. Read More

Stanford, Veterans Affairs Announce Intent to Develop Comprehensive Cancer Center

Stanford Cancer Institute The U.S. Department of Veterans Affairs Palo Alto Health Care System and Stanford Medicine have announced a collaboration on a project to potentially plan, build, and operate a National Cancer Institute-designated joint cancer care and research center on the VA Palo Alto campus. Read More
Mustian Named Associate Director for Population Science

Mustian Named Associate Director for Population Science

Wilmot Cancer Institute, UR Medicine Karen Mustian, PhD, MPH, a longtime leader at the Wilmot Cancer Institute, has been promoted to associate director of population science. She joined the University of Rochester Medical Center in 2003 as a research assistant professor and the inaugural fellow in the URMC National Cancer Institute-funded Cancer Control Training Program. Read More

$3.9 Million Grant Funds E-Cigarette Flavoring Research

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute A new $3.9 million grant from the U.S. Food and Drug Administration will allow researchers with the Center for Tobacco Research at The Ohio State University Comprehensive Cancer Center to evaluate effects of e-cigarette flavors on the smoking behaviors of current adult smokers. Read More

Young Native Hawaiians, Pacific Islanders Face Highest Cancer Death Rates

University of Hawai'i Cancer Center, University of Hawai'i at Mānoa Due to changes in U.S. Census reporting, researchers have found that Native Hawaiians and Pacific Islanders between the ages of 20 and 49 experience the highest rates of cancer death among people their age, more than any other racial group in the U.S. Read More

Hepatocellular Carcinoma Focus of Federal Grant

UCLA Jonsson Comprehensive Cancer Center Researchers from the UCLA Jonsson Comprehensive Cancer Center have received a $3.3 million grant from the National Institutes of Health to find a more effective way to detect hepatocellular carcinoma. The research team proposes a new approach using extracellular vesicles. Read More
NCI Journal Publishes AACI Report on COVID 19 Impact on Clinical Trials

NCI Journal Publishes AACI Report on COVID-19 Impact on Clinical Trials

A report published last month in the Journal of the National Cancer Institute (JNCI) Cancer Spectrum shares the results of an AACI survey on the impact of COVID-19 on cancer clinical trials offices. Lead authors are Thomas J. George, MD, FACP, University of Florida Health Cancer Center; Tara L. Lin, MD, The University of Kansas Cancer Center; and Theresa L. Werner, MD, Huntsman Cancer Institute, University of Utah. Pictured, clockwise from top right: Drs. Thomas J. George, Theresa L. Werner, a…
Pinpointing Pain Is It Cancer or Cancer Treatment

Pinpointing Pain: Is It Cancer or Cancer Treatment?

Fred Hutchinson Cancer Center Distinguishing side effects of cancer treatment from potential metastatic recurrence can be difficult. In a Q&A, Hanna Hunter, MD, medical director of cancer rehabilitation at Fred Hutchinson Cancer Center, shares best practices on how doctors and patients can work together to manage pain symptoms. Read More

Studies Examine Effect of Cancer on Work and Finances

The University of Kansas Cancer Center In the United States, cancer is among the most expensive medical conditions to treat. National costs for cancer care were estimated to be $190.2 billion in 2015. For people with cancer, the mounting medical expenses can lead to a startling side effect: financial toxicity. Several studies show that cancer patients and survivors are more likely to experience financial toxicity than people without cancer. Read More
HPV Vaccine Cost Reimbursement Could Hinder Vaccine Access Study Suggests

HPV Vaccine Cost Reimbursement Could Hinder Vaccine Access, Study Suggests

Hollings Cancer Center, Medical University of South Carolina MUSC Hollings Cancer Center researcher Kalyani Sonawane, PhD, and a team of researchers from South Carolina and Texas decided to quantify private insurance reimbursement rates for the HPV vaccine after several qualitative studies noted that health care providers were dissatisfied with HPV vaccine reimbursement by private insurance companies. Read More

Existing Drug Shows Promise Treating Most Prevalent Type of Lung Cancer

UK Markey Cancer Center A UK Markey Cancer Center research team identified an existing cancer drug that shows promise as a treatment for the most common type of non-small cell lung cancer. The study shows that the Food and Drug Administration-approved medication crizotinib (also known by its name brand, Xalkori) is effective at inhibiting the growth of non-small cell lung cancer with the most common genetic mutations. Read More
Reddy Appointed Chair in Pancreatic Cancer Surgery

Reddy Appointed Chair in Pancreatic Cancer Surgery

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center is proud to announce that Sanjay S. Reddy, MD, FACS, has been appointed to the Marvin S. Greenberg, MD, Chair in Pancreatic Cancer Surgery. Dr. Reddy also serves as program director of the Complex General Surgical Oncology Fellowship, clinical director of the gastrointestinal service line, and co-director the Pancreatic Cancer Institute. Read More

Grant Supports Study of Imaging Surveillance Strategies to Optimize Lung Cancer Outcomes

University of Florida Health Cancer Center With a $3.2 million grant from the National Cancer Institute (NCI), investigators from the newly NCI-designated UF Health Cancer Center and the University of Michigan Rogel Cancer Center will work to close evidence gaps in lung cancer care delivery. Over the five-year project, the team will examine the effectiveness of imaging surveillance strategies based on community-identified needs. Read More
A Novel Approach Towards a Vaccine for Relapsing Acute Myeloid Leukemia

A Novel Approach Towards a Vaccine for Relapsing Acute Myeloid Leukemia

UCSF Helen Diller Family Comprehensive Cancer Center Karin Gaensler, MD, continues her pursuit of a therapeutic cancer vaccine with the development of TriLeukeVax, an engineered autologous leukemia vaccine for stimulating cytolytic immune responses to residual leukemic stem cells. The vaccine would provide a new option for older patients relapsing with adult acute myelogenous leukemia – also known as acute myeloid leukemia. Read More

DEI Summit to Be Held in Conjunction With AACI/CCAF Annual Meeting

In partnership with the American Cancer Society and the Cancer Center DEI Network, AACI will hold the second Diversity, Equity, and Inclusion (DEI) Summit on Saturday, September 30, in conjunction with the 2023 AACI/CCAF Annual Meeting at the Salamander Washington DC. Registration for the summit opens Friday, August 4. Read More

Radiation Oncology Center Open, Proton Therapy to Come

UAMS Winthrop P. Rockefeller Cancer Institute The UAMS Winthrop P. Rockefeller Cancer Institute has opened a new radiation oncology center with expanded capabilities to provide advanced radiation treatments for children and adults with cancer, including the state’s first proton center. The $65 million, 58,000-square-foot structure was built to accommodate three new linear accelerators. Read More

Study Examines Later Cardiac Complications From Pediatric Radiation Therapy

Winship Cancer Institute of Emory University A new study led by a Winship Cancer Institute researcher demonstrates for the first time that applying the same radiation therapy dose to the heart’s substructures as a uniform dose to the whole heart in children with cancer puts them at higher risk for future heart complications. Read More

Overweight BMI Linked to Better Outcomes in Patients With Head and Neck Cancer

Roswell Park Comprehensive Cancer Center Researchers at Roswell Park Comprehensive Cancer Center are shedding light on how Body Mass Index (BMI) impacts treatment response, risk of recurrence, and survival in patients with head and neck cancer. Their retrospective study found that head and neck cancer patients with an overweight BMI had better outcomes than those with a normal or obese BMI. Read More

Liquid Biopsy May Help Identify HPV-Associated Oropharyngeal Cancer

The Tisch Cancer Institute at Mount Sinai Analysis of circulating human papillomavirus (HPV) tumor DNA and tumor DNA fragment (tumor tissue–modified viral [TTMV]-HPV DNA) using a commercially available liquid biopsy test appears to have high specificity for identifying oropharyngeal squamous cell carcinoma, though sensitivity is concerning, data from a retrospective observational cohort study suggested. Read More

Changing the Way Immune-Based Cancer Drugs Are Delivered Could Reduce Costs by 14 Percent

University of Michigan Rogel Cancer Center An analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered. Read More
Medina Kauwe Named Inaugural Chair in Medical Discovery

Medina-Kauwe Named Inaugural Chair in Medical Discovery

Cedars-Sinai Cancer Cedars-Sinai has named Lali Medina-Kauwe, PhD, as the inaugural holder of the Carol Moss Foundation Chair in Medical Discovery. Support from the foundation will enable Dr. Medina-Kauwe to advance innovative research in nanomedicine, the engineering of tiny particles to prevent and treat disease. Read More
Funding Received to Explore Pre Op Health in Native American Cancer Patients

Funding Received to Explore Pre-Op Health in Native American Cancer Patients

The University of Arizona Cancer Center Jennifer Erdrich, MD, MPH, was recently awarded a $1.3 million Mentored Clinical Scientist Research Career Development Award (K08) from the National Cancer Institute to study the effectiveness of lifestyle interventions in American Indian patients with obesity-related solid tumor cancers who are preparing for surgery. Read More
Promote Your Cancer Center With an AACICCAF Annual Meeting Program Ad

Promote Your Cancer Center With an AACI/CCAF Annual Meeting Program Ad

AACI invites you to promote your cancer center by purchasing an ad in the 2023 AACI/CCAF Annual Meeting digital program book. The program book offers an excellent opportunity to showcase your center while supporting the annual meeting, October 1-3 in Washington, DC. Read More

New Imaging Technology May Reduce Surgeries for Rectal Cancer Patients

Siteman Cancer Center A team of researchers from Siteman Cancer Center is developing a new imaging technology that could directly reduce the number of unnecessary surgeries for rectal cancer and improve patients’ quality of life. This project is funded by a four-year $1.75 million grant from the National Institutes of Health. Read More
Researcher Provides Voice for State Residents in Cancer Clinical Trials

Researcher Provides Voice for State Residents in Cancer Clinical Trials

University of Hawai'i Cancer Center, University of Hawai'i at Mānoa University of Hawaiʻi Cancer Center researcher, Erin Bantum, PhD, has been re-elected to serve another three-year term on the National Cancer Institute’s Symptom Management and Quality of Life Steering Committee. This committee addresses the design, prioritization, and evaluation of concepts for Phase II and Phase III clinical trials to control cancer symptoms and cancer treatment side effects. Read More

Study Finds Unexpected Mechanism of Cancer Cell Spread

USC Norris Comprehensive Cancer Center A surprising finding from USC reveals key details about how cancer cells metastasize and suggests new therapeutic approaches for halting their spread. The research centers on a cellular chaperone protein known as GRP78, which helps regulate the folding of other proteins inside cells. Read More
Novel Prostate Cancer Therapy Receives FDA Approval

Novel Prostate Cancer Therapy Receives FDA Approval

Huntsman Cancer Institute at the University of Utah Neeraj Agarwal, MD, FASCO, presidential endowed chair of cancer research at Huntsman Cancer Institute, received approval by the U.S. Food and Drug Administration for a new prostate cancer treatment. The treatment combines two cancer drugs, enzalutamide and talazoparib. Read More

New Approach Developed to Strengthen CAR T-Cell Therapy for Cancer Treatment

Yale Cancer Center, Yale School of Medicine Using a new approach, Yale Cancer Center researchers at Yale School of Medicine have found a new way to substantially improve the effectiveness of CAR T-cell therapy. The researchers focused on a part of the immune system called the cytotoxic T-lymphocyte-associated antigen-4 cytoplasmic tail and fused it with CAR T cells. Read More

KIPA Potentially Predicts Chemotherapy Response in Triple-Negative Breast Cancer

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple-negative breast cancer to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis. Read More

Gene Mutations Linked to Hereditary Kidney Cancer Predisposition But Potential Pitfall Identified

UCLA Jonsson Comprehensive Cancer Center Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome that increases the risk of kidney cancer. Read More
Russell Named Chief Quality Officer

Russell Named Chief Quality Officer

Winship Cancer Institute of Emory University Maria C. Russell, MD, has been named chief quality officer for Winship Cancer Institute of Emory University. She joined the Emory faculty in 2012 and her clinical practice focuses on complex gastrointestinal and hepatobiliary malignancies. Read More

$1.2 Million Awarded to Study Impact of Nutrition on Children's Behavioral, Mental Health Conditions

UAMS Winthrop P. Rockefeller Cancer Institute The University of Arkansas for Medical Sciences’ (UAMS) Center for the Study of Obesity will lead a $1.2 million, multiorganization, three-year research project examining how the availability of school meals benefits the mental and behavioral status of youths. Read More

Study Finds New Potential Therapy Option for Patients with Chronic Lymphocytic Leukemia

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Researchers continue to refine and improve targeted drug therapies that have changed the most common form of adult leukemia from an incurable to a chronic condition. New published data offers another treatment option for patients who have stopped responding to the first and second generation drugs. Read More

Vaccine Plus Immunotherapy and Antibody Spark Immune System Response in Pancreatic Cancers

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, increases the amount of cancer-killing immune system T cells in the tumors, and appears effective when given two weeks prior to cancer-removal surgery. Read…

Study Reveals New Clue to Gastric Cancer

Vanderbilt-Ingram Cancer Center Fibroblast cells play key roles in the repair of damaged tissue and in pathological scarring. Now, researchers at Vanderbilt University Medical Center have uncovered evidence of their direct involvement in the development of gastric cancer. Read More

Missing a Rare Cause of Hereditary Cancer

Cedars-Sinai Cancer New research from Cedars-Sinai Cancer investigators could warrant reconsideration of current screening guidelines to include a poorly recognized cause of Lynch syndrome, the most common cause of hereditary colorectal and endometrial cancers. Their study concluded that the guidelines leave a significant number of patients undiagnosed. Read More

Addressing Health in Areas Characterized by Persistent Poverty

Huntsman Cancer Institute at the University of Utah The Center for Health Outcomes and Population Equity at Huntsman Cancer Institute and the University of Utah, in partnership with the Montana State University Center for American Indian and Rural Health Equity, received a grant for Cancer Control in Persistent Poverty Areas from the National Cancer Institute. The new grant is part of the National Cancer Moonshot Initiative. Read More

Project Aims to Create Dormant Cancer Cell Biosensor

The Tisch Cancer Institute at Mount Sinai Jose Javier Bravo-Cordero, PhD, received a grant from the National Cancer Institute for "Intersectional Genetics-Based Biosensors for Dormant Cancer Cells." The goal is to devise a dormant cancer cell biosensor by using intersectional genetics and synthetic biology technologies that will allow the identification, molecular profiling, and genetic manipulation of dormant cancer cells in vivo. Read More
David Alberts a Legacy of Encouragement Innovation and Scientific Rigor

David Alberts: a Legacy of Encouragement, Innovation and Scientific Rigor

The University of Arizona Cancer Center David Alberts, MD, a founding member of the University of Arizona Cancer Center and a past member of AACI’s Board of Directors, passed away on July 29 at the age of 83. He developed the center’s Cancer Prevention and Control Program served as the center’s director from 2005 until his retirement in 2013 and continued his work part-time until 2017. Read More
Birrer Contributes to Major Ovarian Cancer Discovery

Birrer Contributes to Major Ovarian Cancer Discovery

UAMS Winthrop P. Rockefeller Cancer Institute Michael Birrer, MD, PhD, director of the UAMS Winthrop P. Rockefeller Cancer Institute, is a senior author of a recently published study identifying a 64-protein-gene signature that can predict primary treatment resistance in patients with high grade ovarian cancer. Read More
Sweasy Selected as AACI President Elect Three Cancer Center Leaders Join Board

Sweasy Selected as AACI President-Elect; Three Cancer Center Leaders Join Board

Joann B. Sweasy, PhD, director of the University of Arizona Cancer Center, has been elected by AACI's membership to serve as vice president/president-elect of the AACI Board of Directors. Three new board members were also chosen: Edward Chu, MD, MMS; Raymond N. DuBois, MD, PhD; and Yolanda Sanchez, PhD. They will replace outgoing board members Roy A. Jensen, MD, and Cornelia Ulrich, MS, PhD. Dr. Sweasy is also finishing her term as a regular board member. Read More
State Approves 815 Million Plan to Build Chicagos First Freestanding Cancer Care and Research Facility

State Approves $815 Million Plan to Build Chicago's First Freestanding Cancer Care and Research Facility

The University of Chicago Medicine Comprehensive Cancer Center The Illinois Health Facilities and Services Review Board approved the University of Chicago Medicine’s plans to build an $815 million, 575,000-square-foot building dedicated to cancer research and care on its medical campus on the city’s South Side. Read More

Increasing Access to Lung Cancer Screening Act

This is legislation to amend title XIX of the Social Security Act to require coverage under State plans under the Medicaid program for annual lung cancer screening with no cost sharing for individuals for whom screening is recommended by U.S. Preventive Services Task Force guidelines, to expand coverage under Medicaid of counseling and pharmacotherapy for cessation of tobacco use, and for other purposes.

Study Finds Improved Survival for Incurable Brain Tumor

University of Michigan Rogel Cancer Center Researchers have found a potential drug candidate that improved outcomes for patients with diffuse midline glioma or diffuse intrinsic pontine glioma, for which there are no effective treatments. The compound, ONC201, nearly doubled survival compared to previous patients. Read More
Clinical Trial Leads to FDA Approval of Novel Cord Blood Therapy

Clinical Trial Leads to FDA Approval of Novel Cord Blood Therapy

Duke Cancer Institute, Duke University Medical Center The U.S. Food and Drug Administration's approval of omidubicel, a new and potentially life-saving stem cell treatment option for adult and pediatric patients with high-risk blood cancer, was backed by promising results from a multi-center international Phase III clinical trial led by Mitchell Horwitz, MD. Read More
Siteman Earns Merit Extension From NCI

Siteman Earns Merit Extension From NCI

Siteman Cancer Center Siteman Cancer Center has earned a Merit Extension Award from the National Cancer Institute (NCI), recognizing continued excellence in cancer care, research, training, prevention and community outreach. The award extends the center's Cancer Center Support Grant for an additional two years and $12 million. Timothy J. Eberlein, MD, is Siteman’s director. Read More
Shariff Receives Community Cancer Centers Innovator Award

Shariff Receives Community Cancer Centers Innovator Award

Duke Cancer Institute, Duke University Medical Center Afreen Shariff, MD, has been selected by the Association of Community Cancer Centers as a 2023 Innovator Award recipient for her work on the effectiveness of electronic consults for immune-related endocrine toxicities. Read More
Pasche Named Karmanos President and Chief Executive Officer

Pasche Named Karmanos President and Chief Executive Officer

Karmanos Cancer Institute, in Detroit, has named Boris C. Pasche, MD, PhD, FACP, president and chief executive officer. Dr. Pasche assumes the role Joseph Uberti, MD, PhD, served on an interim basis following the retirement of Gerold Bepler, MD, PhD. Dr. Pasche joins Karmanos from Wake Forest Baptist Health in Winston-Salem, NC. Read More
New President Appointed

New President Appointed

City of Hope Comprehensive Cancer Center Marcel van den Brink, MD, PhD, has been appointed president of City of Hope Los Angeles and National Medical Center, after serving 24 years at Memorial Sloan Kettering Cancer Center. Current president Michael Caligiuri, MD, a past president of AACI, will remain at City of Hope and transition to focus full time on his laboratory research. Read More
Huq Receives Top Award From American Association of Physicists in Medicine

Huq Receives Top Award From American Association of Physicists in Medicine

UPMC Hillman Cancer Center Saiful Huq, PhD, FAAPM, FInstP, received the William D. Coolidge Gold Medal Award from the American Association of Physicists in Medicine for his distinguished career and significant impact on the science and practice of medical physics. Read More

SALUD Study Examines Health Disparities for Latino Survivors of Childhood Cancer

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Researchers at Baylor College of Medicine and Texas Children’s Cancer Center were awarded more than $7.6 million over four years from the National Cancer Institute to comprehensively study late effects of childhood cancer in a diverse population of childhood cancer survivors, including their medical, neurocognitive and psychosocial outcomes. Read More

Project to Study How Sex Differences Affect Bladder Cancer

Cedars-Sinai Cancer Cedars-Sinai Cancer investigators are spearheading a project, funded by a five-year, $11.2 million grant from the National Cancer Institute, to advance scientific knowledge of how biological differences between men and women affect bladder cancer. Read More

Consent Document Translation Costs May Limit Clinical Trial Participation by Underrepresented Groups

UCLA Jonsson Comprehensive Cancer Center Cancer research centers conducting clinical trials could enroll more patients from underrepresented racial and ethnic groups by placing greater emphasis on relieving investigators of the costs of translating consent documents into languages other than English, according to a UCLA Jonsson Comprehensive Cancer Center study. Read More
LILAC Grant Enables Purchase of Key Instruments to Assess Lipid Regulation in Cancer

LILAC Grant Enables Purchase of Key Instruments to Assess Lipid Regulation in Cancer

Stony Brook Cancer Center Daniel Canals, PhD, has received a grant from the Long Island League to Abolish Cancer (LILAC) for the purchase of two cutting-edge instruments that enable him and colleagues to better understand how lipids are regulated in cancer, and in turn, the many functions that lipids perform in cancer cells. Read More
Scientists Employ AI to Predict Brain Cancer Outcomes

Scientists Employ AI to Predict Brain Cancer Outcomes

Stanford Cancer Institute Oliver Gevaert, PhD, and colleagues recently developed an artificial intelligence model that assesses stained images of glioblastoma tissue to predict the aggressiveness of a patient’s tumor, determine the genetic makeup of the tumor cells, and evaluate whether substantial cancerous cells remain after surgery. Read More

New Machine-Learning Method May Aid Personalized Cancer Therapy

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Deep-learning technology developed by a team of Johns Hopkins engineers and cancer researchers can accurately predict cancer-related protein fragments that may trigger an immune system response. If validated in clinical trials, the technology could help scientists overcome a major hurdle to developing personalized immunotherapies and vaccines. Read More

Estrogen Receptor Mutation Study Suggests Potential Treatments for Endometrial Cancers

Huntsman Cancer Institute at the University of Utah Researchers at Huntsman Cancer Institute identified potential new treatment options for people with endometrial cancer. The study discovered that estrogen receptor mutations found in endometrial cancers cause large changes in endometrial cancer cells. Read More
Associate Chief Medical Officer Hired

Associate Chief Medical Officer Hired

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center is pleased to announce the hiring of Nkemdilim Mgbojikwe, MD, as associate chief medical officer. She joins the center from Johns Hopkins Hospital. Read More

Immunotherapy Drug Combo Helps Extend the Lives of Patients With Metastatic Melanoma

UCLA Jonsson Comprehensive Cancer Center A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors. Read More
RNA Stability May Play a Role in Prostate Cancer

RNA Stability May Play a Role in Prostate Cancer

Fred Hutchinson Cancer Center Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from researchers in the lab of Andrew Hsieh, MD. Read More
Salloum Named Associate Director for Community Outreach and Engagement

Salloum Named Associate Director for Community Outreach and Engagement

University of Florida Health Cancer Center Ramzi Salloum, PhD, a cancer implementation science researcher with a focus on tobacco control, has been named associate director for community outreach and engagement at the University of Florida Health Cancer Center. Read More
Chair Vice Chair Named for Department of Immunology and Immunotherapy

Chair, Vice Chair Named for Department of Immunology and Immunotherapy

The Tisch Cancer Institute at Mount Sinai Miriam Merad, MD, PhD, has been named chair, and Brian Brown, PhD, vice chair, of a newly established Department of Immunology and Immunotherapy at the Icahn School of Medicine at Mount Sinai. Drs. Merad and Brown are integral members of Mount Sinai’s Tisch Cancer Institute. Read More