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Scientists Identify How a Biological Pathway Leads Stem Cells to Die or Regenerate

Cedars-Sinai Cancer A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead stem cells—cells from which other cells in the body develop—to die or regenerate. Read More

Scientists Develop Novel mRNA Delivery Method Using Extracellular Vesicles

The University of Texas MD Anderson Cancer Center A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles. The new technique has the potential to overcome many of the delivery hurdles faced by other promising mRNA therapies. Read More

Quality of Treatment for Lung Cancer Varies Widely Across U.S.

Siteman Cancer Center A study from Siteman Cancer Center found the quality of care for lung cancer in the U.S. varies widely, with significantly worse outcomes among patients whose surgeries fall short of established treatment guidelines. After examining five surgical quality metrics based on guidelines established by the National Comprehensive Cancer Network and other cancer groups, researchers found that adherence to these quality metrics was associated with improved overall survival r…

Neuronal Molecule Makes Prostate Cancer More Aggressive

Sidney Kimmel Cancer Center at Jefferson Health Researchers have discovered key molecular players that drive prostate cancer to progress into a highly aggressive form of the disease called neuroendocrine prostate cancer that currently has no effective treatment. Read More

Yang Joins Markey as Chair of Radiation Medicine

UK Markey Cancer Center The University of Kentucky College of Medicine is excited to announce that Eddy Shih-Hsin Yang, MD, PhD, will join the college as the new chair of the department of radiation medicine and the Markey Cancer Foundation Endowed Chair in Radiation Medicine. Dr. Yang is joining the College of Medicine from the University of Alabama at Birmingham. Read More
Associate Director of Research Administration Appointed

Associate Director of Research Administration Appointed

Hollings Cancer Center, Medical University of South Carolina Travis Poole, MHA, has been appointed as associate director of research administration at MUSC Hollings Cancer Center. Poole works closely with the director and members of senior and programmatic leadership to build and support the research infrastructure crucial to the cancer center's mission. Read More

New Approach Outperforms Existing Cancer Susceptibility Models

Vanderbilt-Ingram Cancer Center Investigators at Vanderbilt University Medical Center and the University of Calgary have devised a new approach for conducting gene-based analyses for cancer susceptibility that outperforms existing models. Their research tested a new model for transcriptome-wide association studies, a gene-based method for investigating susceptibility to cancer and other complex diseases. Read More

Findings Could Help Prevent Side Effects for Breast Cancer Patients

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients. The work done by the Schneider lab at the Vera Bradley Foundation Center for Breast Cancer Research at the IU Melvin and Bren Simon Comprehensive Cancer Center and led by Xi Wu, PhD. Read More

Certain Gene Signaling Rewires Tumors After Immunotherapy

University of Michigan Rogel Cancer Center Researchers from the University of Michigan Rogel Cancer Center have identified a mechanism for why a subset of patients’ tumors grow, rather than shrink, when faced with immunotherapy. They found that tumors with hyperprogression after immunotherapy exhibited elevated levels of fibroblast growth factor 2 and beta-catenin signaling. Read More
Moul AUA Award Announced

Moul AUA Award Announced

Duke Cancer Institute, Duke University Medical Center Retired colonel and Duke Cancer Institute member Judd Moul, MD, has been named to receive a Distinguished Contribution Award for his "prolific contributions and leadership in prostate cancer research and dedicated military service" from the American Urological Association. Read More
Graduate Student Recognized With ASH Abstract Achievement Award

Graduate Student Recognized With ASH Abstract Achievement Award

Fox Chase Cancer Center, Temple Health Billy Truong, a doctoral candidate at Fox Chase Cancer Center, was awarded the American Society of Hematology (ASH) Abstract Achievement Award for a poster that he presented at the 64th ASH Annual Meeting and Exposition. His project addresses a critical gap in knowledge for mitogen-activated protein kinase-targeted therapy. Read More

Email Fraud Reminder From AACI

Association of American Cancer Institutes AACI recently received a fraudulent email message that incorporated AACI’s domain name. Please remain alert to possible phishing and email scams, especially if you receive unsolicited messages, attachments, and requests for replies. Read More

Study Reveals How Chronic Blood Cancer Transitions to Aggressive Disease

Siteman Cancer Center Researchers at Siteman Cancer Center have identified an important transition point in the shift from chronic to aggressive leukemia, showing that blocking a key molecule in the transition pathway prevents this dangerous disease progression in mice with models of the disease and in mice with tumors sampled from human patients. Read More

Older Patients Left Behind in Progress Against Lung Cancer

Yale Cancer Center, Yale School of Medicine Although widespread use of immune checkpoint inhibitors in patients with advanced lung cancer has led to meaningful improvements in survival in younger patients, older patients have not experienced similar survival benefits, new research from Yale Cancer Center shows. Read More
Bravo Cordero Elected MRS Secretary

Bravo-Cordero Elected MRS Secretary

The Tisch Cancer Institute at Mount Sinai Jose Javier Bravo-Cordero, PhD, has been elected secretary of the Metastasis Research Society (MRS), which supports progressive research on processes fundamental to metastasis. Dr. Bravo-Cordero is an associate professor of medicine, hematology and medical oncology in the Icahn School of Medicine at Mount Sinai. He served as a member of the MRS board from 2020-2022. Read More

UVA, Community Health Centers Expand Cancer Screenings for Underserved

University of Virginia Cancer Center To expand access to cancer screenings for underserved groups in three regions of Virginia, UVA Cancer Center is establishing partnerships with community health centers serving those areas. The partnerships are supported by $500,000 grants from the U.S. Department of Health and Human Services to improve equity in cancer screenings. The three health centers serve all patients, regardless of their insurance status or ability to pay. Read More
AACI Supporter Message Vitalief

AACI Supporter Message: Vitalief

We are addressing the healthcare human capital epidemic with innovative solutions that help you conduct research and clinical trials successfully. Visit us at Vitalief.com. Learn More
Neutrophil Activating Therapy for The Treatment of Cancer

Neutrophil-Activating Therapy for The Treatment of Cancer

Stanford Cancer Institute Edgar Engleman, MD, is the senior author on a study demonstrating that activated neutrophils can be harnessed to induce eradication of tumors and reduce metastatic seeding through the combined actions of tumor necrosis factor, CD40 agonist, and tumor-binding antibody in laboratory mice. The study's data establish neutrophils as potent anti-tumor immune mediators.   Read More
City of Hope Earns Highest Ranking From NCI

City of Hope Earns Highest Ranking From NCI

City of Hope Comprehensive Cancer Center City of Hope Comprehensive Cancer Center has received the highest ranking possible—"exceptional"—by the National Cancer Institute (NCI), and was awarded more than $23 million in competitive funding through renewal of its NCI Cancer Center Support Grant to support research, cancer training and education, and community outreach over the next five years. Steven T. Rosen, MD, is the cancer center's director. Read More
Formation of New Department of Urology Announced

Formation of New Department of Urology Announced

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center has formed a new Department of Urology that will be chaired by Alexander Kutikov, MD, FACS. On average, the department publishes and contributes to over 100 peer-reviewed publications, book chapters, and abstracts every year. Fox Chase urology is also a nationally recognized hub for the surgical training of residents and Society of Urologic Oncology and Genitourinary Reconstruction Fellows. Read More

MD Anderson Receives Nearly $19.4 Million in CPRIT Funding

The University of Texas MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center has been awarded 15 grants totaling $19.38 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer research projects across the institution. Read More
Toll Named President of the Society for Research on Nicotine Tobacco

Toll Named President of the Society for Research on Nicotine & Tobacco

Hollings Cancer Center, Medical University of South Carolina As a young researcher fresh out of graduate school, MUSC Hollings Cancer Center’s Benjamin Toll, PhD, was thrilled to present his research at the annual conference of the Society for Research on Nicotine & Tobacco (SRNT) in 2002. Fast forward 21 years and he’s now taking the helm. Dr. Toll was recently elected president-elect of SRNT and will serve a three-year term. Read More
Weiner to Step Down as Director of Holden Henry to Serve as Interim Director

Weiner to Step Down as Director of Holden; Henry to Serve as Interim Director

George Weiner, MD, director of University of Iowa (UI) Holden Comprehensive Cancer Center, will step down from the leadership role on March 31. Dr. Weiner is a past president of AACI. Michael Henry, PhD, deputy director and professor in the UI Department of Molecular Physiology and Biophysics, will serve as interim director of the cancer center, effective April 1. Read More
Register Today for the 15th Annual AACI CRI Meeting

Register Today for the 15th Annual AACI CRI Meeting

Registration is open for the 15th Annual AACI Clinical Research Innovation (CRI) Meeting, which will be held June 26-28 at the Loews Chicago O'Hare Hotel in Rosemont, IL. This year’s meeting theme, "Taking Innovations in Clinical Research From Abstract to Reality," aims to stimulate cancer center interactions and maximize resources by creating opportunities for peer-to-peer networking and collaboration. Read More

Ohio State Interdisciplinary Research Building to be Named for Pelotonia

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Pending approval by The Ohio State University Board of Trustees, a new interdisciplinary research facility in the university’s Carmenton innovation district will be named Pelotonia Research Center. The naming is in recognition of Pelotonia’s philanthropic support for cancer research at OSUCCC–James. Read More

Trial Shows Significant Disease-free Survival for Patients Diagnosed With Non-small Cell Lung Cancer

Yale Cancer Center, Yale School of Medicine New data from a Yale Cancer Center-led clinical trial shows improved rates of survival and reduced risk of recurrence in patients taking osimertinib, a targeted therapy for non-small cell lung cancer (NSCLC). The phase III ADAURA clinical trial assessed the safety and efficacy of osimertinib in patients with surgically removed (completely resected) stage IB-IIA NSCLC, who were previously treated with or without adjuvant chemotherapy. …
Hatcher to Establish Office of Inclusivity Diversity Equity and Accessibility

Hatcher to Establish Office of Inclusivity, Diversity, Equity and Accessibility

The University of Arizona Cancer Center Jennifer Hatcher, PhD, MPH, MSN, has been appointed associate director of Inclusivity, Diversity, Equity and Accessibility for the University of Arizona Cancer Center. The appointment initiates establishment of a new office of diversity, equity, and inclusion at the center. Dr. Hatcher currently oversees community outreach and engagement and will serve as interim in that capacity while a national search is conducted. Read More
An Extraordinary Woman in Cardiothoracic Surgery

An Extraordinary Woman in Cardiothoracic Surgery

Duke Cancer Institute, Duke University Medical Center Duke Cancer Institute surgical oncologist Betty Tong, MD, MHS, MSME, BME, has won the inaugural "Extraordinary Women in Cardiothoracic Surgery Award" established by the Society of Thoracic Surgeons and Women in Thoracic Surgery. Read More
AACI Returns to Capitol Hill to Advocate for Cancer Research Funding

AACI Returns to Capitol Hill to Advocate for Cancer Research Funding

Registration is now open for AACI's joint Hill Day with the American Association for Cancer Research (AACR), which will take place in person in Washington, DC, on Thursday, May 18. AACI is also accepting recommendations for Cancer Research Ally Award nominees and Hill Day speakers. Read More

$11 Million NIH SPORE Award to Continue Research Excellence in Head and Neck Cancer

UPMC Hillman Cancer Center The University of Pittsburgh was awarded a five-year, $11.2 million grant from the National Institutes of Health (NIH) to support a Head and Neck Cancer Specialized Program of Research Excellence (SPORE). The award will be led by Robert L. Ferris, MD, PhD, director of UPMC Hillman Cancer Center, and Heath Skinner, MD, PhD, chair and associate professor, Department of Radiation Oncology. Read More
Researchers Recognized as Endowed Chairs

Researchers Recognized as Endowed Chairs

Huntsman Cancer Institute at the University of Utah Huntsman Cancer Institute's Alana Welm, PhD, received a five-year extension in her role as Ralph E. and Willia T. Main Presidential Endowed Chair in Cancer Research; Aik Choon Tan, PhD, was named the Jon and Karen Huntsman Presidential Professor in Cancer Research; and Brad Cairns, PhD, was named the inaugural Jon M. Huntsman Presidential Endowed Chair in Cancer Research. Read More
New Members Join PCLI Steering Committee

New Members Join PCLI Steering Committee

Seven new members have been selected to join AACI’s Physician Clinical Leadership Initiative (PCLI) Steering Committee. The new members’ terms began February 1. PCLI pursues a variety of objectives, including developing better methods to disseminate information across cancer centers, identifying and addressing oncology care model barriers, faculty career development, and measuring quality. Read More

New Analysis Sheds Light on Link Between Ovulation and Ovarian Cancer

UPMC Hillman Cancer Center Women who ovulate for longer over their lifetimes have a higher risk of developing ovarian cancer, suggesting that suppressing ovulation can lower this risk. A new international study offers new clues as to how oral contraceptives, pregnancy, and breastfeeding impact ovarian cancer risk beyond simply suppressing ovulation and how this link may vary among different ovarian cancer subtypes. Read More

Markey Research to Inform Regulations on Latest Tobacco Products

UK Markey Cancer Center A new University of Kentucky Markey Cancer Center study will help inform policy on the sale and marketing of two different tobacco products recently introduced to the U.S. market. The study is one of the first to examine the retail availability of disposable e-cigarettes and oral nicotine pouches and gives an early indication the products are targeted to different audiences.   Read More

Invention: A Blood Test to Unlock Prostate Cancer Mysteries

Cedars-Sinai Cancer Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers – even in microscopic amounts. Their work suggests that this "liquid biopsy" test could spare many patients unnecessary treatment-related side effects, directing them instead to effective therapies that could prolong their lives. Read More
Berlin Named Director of Division of Hematology and Oncology

Berlin Named Director of Division of Hematology and Oncology

Vanderbilt-Ingram Cancer Center Jordan Berlin, MD, Ingram Professor of Cancer Research, has been named director of Vanderbilt’s Division of Hematology and Oncology. The appointment was effective January 1, but Dr. Berlin had served as interim director for six months prior to that date. Read More

Baylor Receives More Than $5.8 Million in CPRIT Funding

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Baylor College of Medicine has been awarded more than $5.8 million in grants by the Cancer Prevention & Research Institute of Texas (CPRIT) to support innovative translational research and cancer treatments. CPRIT awarded more than $90 million in grants to institutions across Texas to advance the fight against cancer, including four grants to Baylor. Read More

Study: Vaping CBD Causes More Severe Lung Damage Than Vaping Nicotine

Roswell Park Comprehensive Cancer Center Vaping cannabidiol (CBD), leads to more severe lung damage than vaping nicotine, according to a study from Roswell Park Comprehensive Cancer Center. Until now, research on the health effects of vaping, or using e-cigarettes, has focused almost exclusively on vaping nicotine as opposed to CBD.   Read More

Study Finds Medicaid Expansion Improves Cancer Survival Outcomes for Young Adults

Winship Cancer Institute of Emory University A large first-of-its-kind study finds that expanded Medicaid coverage under the Affordable Care Act (ACA) leads to better survival outcomes for young adults aged 18-39 newly diagnosed with cancer, particularly those identified as of Hispanic ethnicity or non-Hispanic Black race. Additionally, young adults with breast cancer and stage IV cancers had pronounced improvements attributable to ACA-expanded Medicaid.   Read More

Researchers Make Major Advance With Cancer-Killing Antibody-Drug Conjugates

University of Florida Health Cancer Center University of Florida researchers have made a significant discovery in the development highly targeted chemotherapies for breast and other cancers. The scientists have spent years developing antibody-drug conjugates, or ADCs, that combine a protective protein and a cancer-killing drug. Recently published findings detail the first time a particular type of cancer-killing "payload" has been used for ADC development. Read More

New Theranostic Treatment for Prostate Cancer Tested

University of New Mexico Comprehensive Cancer Center The UNM Comprehensive Cancer Center will soon be examining the potential for using cutting-edge radioisotope technology called 177 Lu-PSMA-617 to treat advanced prostate cancer. The center will be one of a few sites in the country participating in a clinical trial to expand the application of theranostic treatment to patients with prostate cancer. This type of treatment is currently used at the cancer center for neuroendocrine tumors. …
Rai to Co lead Tumor Biology Research Program

Rai to Co-lead Tumor Biology Research Program

Sylvester Comprehensive Cancer Center, University of Miami Priyamvada Rai, PhD, is the new Tumor Biology Research Program co-leader at Sylvester Comprehensive Cancer Center, part of UHealth – University of Miami Health System. In her role, Dr. Rai will boost interactions and collaborations among Sylvester’s researchers to better understand how cancer cells behave. Read More
Associate Director for Translational Sciences Appointed

Associate Director for Translational Sciences Appointed

LSU LCMC Health Cancer Center Yaguang Xi, MD, PhD, MBA, has been appointed associate director for translational sciences at the LSU-LCMC Cancer Center. Dr. Xi is a professor and vice chair for research in the Department of Genetics at LSU Health Sciences Center. His research interests include cancer therapeutics, cancer chemoprevention, health disparities, metastasis, immunotherapy, and new drug development. Read More

Fox Chase Receives Sixth Consecutive Magnet Designation for Nursing Excellence

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center has achieved Magnet designation for nursing excellence from the American Nurses Credentialing Center for the sixth consecutive time. Fox Chase has held Magnet status continuously since 2000, when it became the first hospital in Pennsylvania and the first specialty hospital in the United States to achieve Magnet designation. Read More

Five Rogel Members Named 2022 AAAS Fellows

University of Michigan Rogel Cancer Center Five University of Michigan Rogel Cancer Center members were elected as 2022 fellows of the American Association for the Advancement of Science. The Rogel fellows are: Thomas Carey, PhD; Joerg Lahann, PhD; Marina Pasca di Magliano, PhD; Donna Martin, MD, PhD; and Duxin Sun, PhD. Read More
New Sustaining Member Prevent Cancer Foundation

New Sustaining Member: Prevent Cancer Foundation

AACI welcomes the Prevent Cancer Foundation® to its sustaining members. The Prevent Cancer Foundation is the only U.S.-based nonprofit organization solely dedicated to cancer prevention and early detection. Founded in 1985, the foundation focuses its work in four areas: research, education, outreach, and advocacy. Learn More

Study Provides an Explanation, Potential Solution for Severe Graft-Versus-Host Disease

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine The severity of immune-mediated intestinal diseases such as graft-versus-host disease or inflammatory bowel diseases is known to be associated with alterations in the gut microbiome, but what leads to such disruption has remained a mystery. Researchers at Baylor College of Medicine and collaborating institutions report that alterations in the gut microbiome are connected to an increase in the oxygen levels in the inte…

Lung Cancer Screening More Cost Effective When Using Risk Model-Based Strategies

The University of Texas MD Anderson Cancer Center Risk model-based lung cancer screening strategies, which select individuals based on personal risk, are more cost effective than current recommendations based solely on age and smoking history, according to a study led by the Cancer Intervention and Surveillance Modeling Network Lung Working Group, which includes researchers from The University of Texas MD Anderson Cancer Center. Read More
PCLI Manuscript Published in ASCO Journal

PCLI Manuscript Published in ASCO Journal

The AACI Physician Clinical Leadership Initiative (PCLI) distributed surveys to understand unintended consequences of the 21st Century Cures Act mandate on the immediate release of clinical information. JCO Oncology Practice has published a report based on the survey’s findings, "Impact of the Immediate Release of Clinical Information Rules on Health Care Delivery to Patients With Cancer." AACI PCLI steering committee member Taher Abu Hejleh, MBBS, is the lead author. Read More

Researchers Identify Possible Approach to Prevent Cancer From Evolving to Resist Treatment

UCLA Jonsson Comprehensive Cancer Center A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. To understand how the cancer genome changes immediately after the initiation of targeted therapy—potentially generating new genetic variants capable of escaping the therapy—the researchers focused on metastatic cutaneous …

Epigenetics and Math Converge to Predict, Intercept Cancer Cell Behavior

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University It is now widely understood that cancer is a disease of acquired defects in genes and gene function. A recently published article addresses new quantitative approaches to better define and measure these defects in gene function, known as epigenetics, and their interplay with the genetic landscape of cancer. Read More
Thompson Receives Grant to Study Cancer Patients Caregivers

Thompson Receives Grant to Study Cancer Patients, Caregivers

Siteman Cancer Center Tess Thompson, PhD, MPH, has received a five-year $1.1 million grant from the National Cancer Institute to study unmet social needs of cancer patients and their caregivers, with the ultimate aim of improving outcomes for both members of a pair. Read More

$1.6 Million Gift Will Establish Endowed Chair in Gynecologic Oncology

UK Markey Cancer Center The University of Kentucky Markey Cancer Center and UK HealthCare has received a $1.6 million gift from the Telford Foundation to establish the John R. van Nagell, Jr. Chair in Gynecologic Oncology. The donation will be matched by $800,000 from UK’s Research Challenge Trust Fund, for a total gift of $2.4 million that will support the senior level faculty position.   Read More
2022 AACI Annual Report Published

2022 AACI Annual Report Published

In 2022, AACI focused on leadership, hosting the inaugural Leadership Diversity and Development Initiative (LDDI) Workshop and its first-ever meeting designed for new cancer center directors. Also in 2022, the association welcomed Ellis Fischel Cancer Center, Houston Methodist Dr. Mary and Ron Neal Cancer Center, Koch Institute for Integrative Cancer Research at MIT, and Northwell Health Cancer Institute. Read the Report

Wirthlin to Lead Huntsman Cancer Foundation

Huntsman Cancer Institute at the University of Utah Huntsman Cancer Foundation Chair and CEO Peter Huntsman has announced that Kim Wirthlin will be president and chief operating officer. During her 16 years of employment at the University of Utah, Wirthlin has worked as the vice president of government relations and as the chief marketing and communications officer for the university’s health care system and Health Sciences. Read More
Translational and Clinical Oncology Research Program Co Leader Named

Translational and Clinical Oncology Research Program Co-Leader Named

Sylvester Comprehensive Cancer Center, University of Miami Jaime Merchán, MD, is the new Translational and Clinical Oncology Research Program co-leader at Sylvester Comprehensive Cancer Center, part of UHealth – University of Miami Health System. Dr. Merchán, who also directs Sylvester’s Phase 1 Clinical Trials Program, is leading the program alongside C. Ola Landgren, MD, PhD, director of the cancer center’s new Myeloma Research Institute. Read More
Mitchell Named Enterprise Vice President for Cancer Disparities

Mitchell Named Enterprise Vice President for Cancer Disparities

Sidney Kimmel Cancer Center at Jefferson Health Edith P. Mitchell, MD, MACP, FCCP, FRCP (London), director of the Center to Eliminate Cancer Disparities, has been named enterprise vice president for cancer disparities at Jefferson Health’s Sidney Kimmel Cancer Center.   Read More
Bhardwaj Jaffee Appointed Associate Directors of the Cancer Research Institute Scientific Advisory Council

Bhardwaj, Jaffee Appointed Associate Directors of the Cancer Research Institute Scientific Advisory Council

The Cancer Research Institute has announced that two members of its scientific advisory council (SAC), Nina Bhardwaj, MD, PhD, of The Tisch Cancer Institute at Mount Sinai, and Elizabeth M. Jaffee, MD, of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, have been appointed SAC associate directors. Read More
Tabung Appointed to National Cancer Advisory Board

Tabung Appointed to National Cancer Advisory Board

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute President Joe Biden has appointed Ohio State University’s Fred Tabung, PhD, MSPH, to the National Cancer Advisory Board. He is one of six individuals from across the United States tapped to serve in this important role to help guide the national cancer research program agenda. Read More
Blobe Elected as AAAS Fellow

Blobe Elected as AAAS Fellow

Duke Cancer Institute, Duke University Medical Center Director of the Duke Cancer Institute Office of Cancer Research Training & Education Coordination, Gerard C. Blobe, MD, PhD, has been elected as a 2022 AAAS Fellow by the American Association for the Advancement of Science. Read More

Researchers Use a New Approach to Hit an 'Undruggable' Target

University of Michigan Rogel Cancer Center The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category. Now, University of Michigan Rogel Cancer Center researchers have found success with a new approach. Read More

Researchers Clarify Role of Blood Cell Mutations in Disease

Vanderbilt-Ingram Cancer Center A research team at Vanderbilt University Medical Center has detailed a stepwise method for analyzing large data sets (more than 550,000 individuals) that can improve dramatically the accuracy of "clonal hematopoiesis of indeterminate potential,” or CHIP, determination. Read More

New AI-Based Biomarker Can Help Predict Immunotherapy Response for Patients with Lung Cancer

Winship Cancer Institute of Emory University In a retrospective study, a team of researchers from several health care systems and universities, including Emory University, has discovered a new artificial intelligence (AI)-derived biomarker that uses routine imaging scans to help predict which patients with lung cancer will respond to immunotherapy.    Read More

Investigators Share Advances in Stem Cell Transplantation, Cellular Therapy at Tandem Meetings

Roswell Park Comprehensive Cancer Center Investigators from Roswell Park Comprehensive Cancer Center were among the experts whose work was highlighted at the 2023 Tandem Transplantation & Cellular Therapy Meetings of the American Society for Transplantation and Cellular Therapy and Center for International Blood and Marrow Transplant Research. Read More

Impact of Cigarette Smoking, Alcohol Consumption on Black Breast Cancer Survivors Explored

Rutgers Cancer Institute of New Jersey Investigators from Rutgers Cancer Institute of New Jersey, together with RWJBarnabas Health, found that a higher risk of mortality in Black breast cancer survivors is associated with a history of cigarette smoking along with regular alcohol consumption at the time of diagnosis. Read More
Shokat Honored for High Impact Cancer Research

Shokat Honored for High-Impact Cancer Research

UCSF Helen Diller Family Comprehensive Cancer Center Kevan Shokat, PhD, has received the Sjöberg Prize from the Swedish Academy of Sciences, the same body that awards the Nobel prizes for physics, chemistry and economics. He was also recently recognized by the National Academy of Sciences with the organization’s annual Award for Scientific Discovery. Read More

Study Finds Disparities in Cancer Genetic Testing

University of Florida Health Cancer Center A study led by UF Health Cancer Center researchers found that Black and Hispanic adults had less knowledge and were less likely to undergo cancer genetic testing than white adults. The researchers compared self-reported cancer genetic testing knowledge and use by race and ethnicity. They also looked at the perceived importance of genetic information for cancer care in relation to the uptake of cancer genetic testing. Read More

Discovery of Cancer-Associated Fibroblast Origin Gives New Direction for Pancreatic Cancer

Hollings Cancer Center, Medical University of South Carolina A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows. This new data is the first to show the cellular origin of normal pancreatic fibroblasts and cancer-associated fibroblasts that influence tumor progression. Read More

Cancer Patients Who Do Not Respond to Immunotherapy Lack Crucial Immune Cells

Siteman Cancer Center Researchers at Washington University School of Medicine in St. Louis have discovered that the difference between people who do and do not respond to immunotherapy may have to do with an immune cell known as CD5+ dendritic cells because they bear the protein CD5 on their outer surfaces. Read More
Bravo Cordero Receives Emerging Leader Award From The Mark Foundation

Bravo-Cordero Receives Emerging Leader Award From The Mark Foundation

The Tisch Cancer Institute at Mount Sinai Jose Javier Bravo-Cordero, PhD, received an Emerging Leader Award from The Mark Foundation for his project, Impact of Dormant Cancer Cells on the Brain Microenvironment. Dr. Bravo-Cordero will use high-resolution imaging technology to understand how dormant cancer cells instruct neuronal tissue at the single cell level. Read More
Mayes Named Chair of NCCN DEI Directors Forum

Mayes Named Chair of NCCN DEI Directors Forum

Stanford Cancer Institute The National Comprehensive Cancer Network (NCCN) has announced that Terrance Mayes, EdD, associate director for diversity, equity & inclusion at the Stanford Cancer Institute, will serve as the inaugural chair of the NCCN Diversity, Equity & Inclusion Directors Forum. Read More
Mark Foundation Recognizes Trowbridge

Mark Foundation Recognizes Trowbridge

The Jackson Laboratory Cancer Center Jennifer Trowbridge, PhD, has received an Emerging Leader Award from The Mark Foundation for Cancer Research. The foundation presented six of these awards, totaling $4.5 million, to outstanding early-career investigators for projects aimed at addressing unmet needs in cancer research. Read More

Study Finds Age-Related Gap in Breast Cancer Treatment Recommendations

Yale Cancer Center, Yale School of Medicine Age-based heuristics, or "rules of thumb," can lead to large differences in breast cancer treatment based on small differences in chronologic age, according to a new analysis of more than 500,000 patient records. Read More

Smarter Breast Cancer Screening Measures Risk Down to Your DNA

UCSF Helen Diller Family Comprehensive Cancer Center A UC San Francisco breast cancer screening study is expanding to reach women as young as 30, with the aim of adding thousands of women who could be at higher risk of developing aggressive cancer. Known as WISDOM 2.0, the study is testing a personalized approach that replaces the standard annual mammogram with recommended screening schedules based on personal risk factors, such as age, genetics, lifestyle, health history and breast dens…

Nominate a Philanthropy Champion by March 31

AACI cancer center directors are invited to submit nominations for the 2023 Champion for Cures Award by Friday, March 31. The award will be presented during the 2023 AACI/CCAF Annual Meeting, October 1-3, at the Salamander Washington DC. Read More
Inaugural DEI Summit Held in San Diego

Inaugural DEI Summit Held in San Diego

In partnership with the American Cancer Society and the Cancer Center DEI Network, AACI supported the inaugural Diversity, Equity, and Inclusion (DEI) Summit. The two-day event, held March 10 and 11, convened cancer center leaders, researchers, and administrators to share insights on how institutions are enhancing DEI efforts, and to address barriers that centers face in carrying out these initiatives. Robert A. Winn, MD, AACI president-elect and director of VCU Massey Cancer Center, shared rem…
AACI Hosts Spring GR Forum at Huntsman Cancer Institute

AACI Hosts Spring GR Forum at Huntsman Cancer Institute

On March 20, AACI held its annual spring Government Relations (GR) Forum at Huntsman Cancer Institute (HCI) in Salt Lake City. The meeting gave AACI government relations representatives and sustaining members an opportunity to gather and tour the Huntsman Cancer Institute and hear from a variety of speakers on cancer-related public policy. Read More
Jill Biden Commends Unique Collaborative Approach at LCRC

Jill Biden Commends Unique Collaborative Approach at LCRC

Louisiana Cancer Research Center After First Lady Jill Biden toured the Louisiana Cancer Research Center, with Center Director Joe W. Ramos, PhD, United States Senator Bill Cassidy, Dr. Laura Cassidy, and U.S. Representative Troy Carter, she told a room packed with researchers and policymakers how impressed she was with the work of LCRC's member institutions and its statewide partner researchers. Read More
Cancer Center Uses Art to Reach Underserved Communities

Cancer Center Uses Art to Reach Underserved Communities

The University of Kansas Cancer Center Sometimes the best way to reach a community is through art. That’s the idea behind The University of Kansas Cancer Center’s new mural being painted by artist Vania Soto on the side of the Guadalupe Centers Middle School in Kansas City, Missouri. The mural is a portrait of four cancer survivors and co-survivors, all from underserved populations, beneath which are painted the words "Clinical Research Needs Representation." Read More
Govindarajan Named Chief of Hematology and Oncology Division

Govindarajan Named Chief of Hematology and Oncology Division

UAMS Winthrop P. Rockefeller Cancer Institute Rangaswamy Govindarajan, MD, hematologist and oncologist at the University of Arkansas for Medical Sciences, has been appointed chief of the Division of Hematology and Oncology at the UAMS Winthrop P. Rockefeller Cancer Institute. Read More
National Cancer Clinical Leadership Role for UH Researcher

National Cancer Clinical Leadership Role for UH Researcher

University of Hawai'i Cancer Center, University of Hawai'i at Mānoa University of Hawaiʻi Cancer Center researcher Stephanie Si Lim, MD, was selected as a member of AACI's Physician Clinical Leadership Initiative (PCLI) Steering Committee. The committee seeks to identify roadblocks in cancer care, ensure quality of services, provide faculty career development, and disseminate information across cancer centers. Read More
Need for Clinical Trial Support Stressed at Cancer Forum

Need for Clinical Trial Support Stressed at Cancer Forum

Vanderbilt-Ingram Cancer Center Cathy Eng, MD, stressed the need for more patient participation and better funding for clinical trials to improve colorectal cancer treatment and outcomes during the White House Cancer Moonshot Colorectal Cancer Forum in March. She was one of four panelists who discussed efforts to improve treatment outcomes during the event. Read More
A New Chapter for DEIJ at Rogel

A New Chapter for DEIJ at Rogel

University of Michigan Rogel Cancer Center Diversity, equity, inclusion, and justice are crucial to Rogel Cancer Center’s mission, from Community Outreach and Engagement programs addressing health care disparities to hiring processes and leadership development. Read More

Wheeler Leads Study to Improve Risk-Based Cancer Screening for HPV

University of New Mexico Comprehensive Cancer Center Cosette Wheeler, PhD, and her team at UNM Comprehensive Cancer Center worked with Becton Dickinson and the New Mexico HPV Pap Registry to conduct one of the largest real-world evidence studies of its kind to support FDA approval of a new HPV Assay that detects 14 high-risk HPV virus types. It reports individual results for six of the 14 high-risk types and three groups of results for the remaining eight high-risk types. Read M…

Troubling Disparities Found in Esophageal Cancer Outcomes

University of Virginia Cancer Center Lower-income people are significantly less likely to receive a potentially lifesaving treatment for the fastest-increasing type of esophageal cancer – and are more likely to die from the disease, new research from UVA Cancer Center reveals. The study highlights troubling socioeconomic disparities in treatment access for early stage esophageal adenocarcinoma, an increasingly common cancer of the food tube that can be cured if treated early but can be f…

Paid Sick Leave Means More People Get Screened for Cancer

UCSF Helen Diller Family Comprehensive Cancer Center An estimated 300,000 additional employees received colorectal cancer screening in a two-year period, following mandated paid sick leave in 57 metropolitan areas across the U.S. About 250,000 additional workers underwent breast cancer screenings in a two-year period after the mandate, according to a study led by UC San Francisco and headed by senior author Julie Ann Sosa, MD. Read More

Investigators Find Disparities in Mesothelioma Survival Due to Social Determinants, Limited Access

Sylvester Comprehensive Cancer Center, University of Miami Treatment outcomes for patients with malignant pleural mesothelioma, a rare cancer commonly known as mesothelioma, are often affected by social determinants of health and overall survival rates could be improved by addressing these health disparities and improving access to specialized care. Read More

Clinical Trial Could Help Men Avoid Surgery to Remove Prostate

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center researchers are recruiting for a clinical trial called PRESERVE that will evaluate the safety and efficacy of the NanoKnife System to destroy prostate cancer cells. One of the measurements of treatment effectiveness is to assess the number of subjects who were able to avoid surgery to completely remove the prostate. Read More
Curseen Named Director of Palliative Medicine Program

Curseen Named Director of Palliative Medicine Program

Winship Cancer Institute of Emory University Kimberly A. Curseen, MD, has been named director of the Palliative Medicine Program at Winship Cancer Institute of Emory University. Dr. Curseen joined Emory in 2015 and has led Winship’s Supportive Oncology Clinic since that time. Read More
New Corporate Roundtable Member Eagle Pharmaceuticals

New Corporate Roundtable Member: Eagle Pharmaceuticals

AACI welcomes Eagle Pharmaceuticals to its Corporate Roundtable. Eagle is a specialty pharmaceutical company working to advance safe and efficient injectable treatments for patients across oncology, critical care, and orphan diseases. The AACI Corporate Roundtable provides a forum for AACI cancer centers to address topics of mutual interest with their pharmaceutical industry colleagues. Learn More

New Program Shows Promise in Reducing Financial Burden of Cancer Care

UK Markey Cancer Center The rising cost of cancer care puts patients and their caregivers at increased risk of experiencing financial toxicity, a term used to describe financial hardship caused by out-of-pocket treatment costs. A new UK Markey Cancer Center study found that the use of a financial navigator can significantly reduce financial toxicity for patients with hematologic cancer and their caregivers. Read More

Clinical Trials Add Beta Blocker to Arsenal Against Esophageal Cancer

Roswell Park Comprehensive Cancer Center Roswell Park researchers have launched two Phase II clinical trials for esophageal cancer. Their goal: to determine whether a beta blocker called propranolol (brand name Inderal) can improve the efficacy of checkpoint inhibitors. Read More
Mc Allister Receives Award for Pancreatic Tumor Microbiome Research

McAllister Receives Award for Pancreatic Tumor Microbiome Research

The University of Texas MD Anderson Cancer Center Florencia McAllister, MD, has been awarded the 2023 Mary Beth Maddox Award and Lectureship from the Texas Academy of Medicine, Engineering, Science and Technology. Her pioneering research on the intra-tumoral bacteria detected in long-term pancreatic cancer survivors led to the discovery of a gut-tumor axis and the use of fecal microbial transplants to improve therapy outcomes. Read More

Study Finds Education and Navigation Increased Cancer Genetic Counseling, Testing

Rutgers Cancer Institute of New Jersey Researchers at Rutgers Cancer Institute of New Jersey have explored informing patients of their potentially increased risk for genetically-inherited cancers and navigating them to receive a cancer genetic risk assessment (genetic counseling and/or testing) through phone-based decision coaching and navigation. Read More

The American Cancer Society, Winship Partner to Accelerate Cancer Research in Georgia

Winship Cancer Institute of Emory University The American Cancer Society (ACS), in partnership with Winship Cancer Institute of Emory University, has announced a new project to significantly accelerate cancer research and improve patient outcomes. Supported by a $6 million, three-year grant from the Robert W. Woodruff Foundation, a cloud-based technical infrastructure is being built to connect Winship experts with ACS population science researchers and relevant biospecimens and data with…

Nominations Open for 2023 Cancer Health Equity Award

Nominations are now being accepted for the 2023 AACI Cancer Health Equity Award. The award was created in 2021 to recognize an individual or group who demonstrates exceptional leadership in promoting health equity, mitigating cancer disparities, and advocating for diversity and inclusion at their cancer center. The nomination period will close on Wednesday, May 31. Read More

Study Reveals New Understanding of How Androgen Therapy Affects Breast Tissue

Cedars-Sinai Cancer New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer. A new study has found that molecular changes observed in the breast tissue of transgender men undergoing androgen therapy may signal the potential for also using the hormone to prevent or treat a type of breast cancer that is fueled by estrogen. Read More