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New Methods Outlined to Identify Personalized Drug Treatments for Breast Cancer

Huntsman Cancer Institute at the University of Utah For years, researchers at Huntsman Cancer Institute have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice to study the tumor’s behavior. Now, the team reports a new, more efficient way to grow these tumors, and they outline a process to test potential drugs to help prioritize clinical therapy choices based on unique tumor characteristics. Read …

Long-Elusive Structure of Key Cellular-Signaling Molecule Found

Stanford Cancer Institute For more than 25 years, researchers around the world have been trying to find the structure of Janus kinases, or JAKs, a class of proteins that play a key role in cellular signaling and that have been tied to many cancers. Now, Stanford School of Medicine researchers have learned the architecture of one of these proteins. Read More

Cerebrospinal Fluid May Be Able to Identify Aggressive Brain Tumors in Children

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University It may be possible to identify the presence of an aggressive brain tumor in children by studying their cerebrospinal fluid, according to new research led by Johns Hopkins Kimmel Cancer Center investigators. Comparing cerebrospinal fluid samples from 40 patients with medulloblastoma and from 11 healthy children without the disease, investigators identified 110 genes, 10 types of RNA, 14 lipids, and several metabolites t…

Cancer Drugs Might Be Able to Target Tuberculosis, Study Finds

Stanford Cancer Institute An unexpected link between tuberculosis and cancer may lead to new drug treatments for the bacterial disease, according to a study led by researchers at Stanford Medicine. The study found that granulomas in the lungs of people with active tuberculosis infections are packed with proteins known to tamp down the body’s immune response to cancer cells or infection. Read More
Prevent Cancer Foundation Grant to Focus on Cervical Cancer Disparities

Prevent Cancer Foundation Grant to Focus on Cervical Cancer Disparities

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center’s Suzanne M. Miller, PhD, a professor in the Cancer Prevention and Control research program, has received a two-year research grant from the Prevent Cancer Foundation to support a project designed to test whether text messaging can effectively reduce urban cervical cancer disparities. Read More

Study Examines Kentucky Lung Cancer Disparities

UK Markey Cancer Center A recent UK Markey Cancer Center study gives more insight into how lung cancer differs in Kentucky compared to other U.S. populations. The research shows that Kentucky has more late-stage diagnoses and worse lung cancer survival rates compared to other states. Read More
Winn Honored With 100 Million Fellowship in His Name

Winn Honored With $100 Million Fellowship in His Name

VCU Massey Comprehensive Cancer Center Bristol Myers Squibb Foundation, National Medical Fellowships, and the American Association for Cancer Research have announced a new name for a $100 million, five-year initiative they launched in 2020: The Robert A. Winn Diversity in Clinical Trials Award Program. The program also received $14 million in funding over the next four years from Gilead Sciences, Inc. Dr. Winn is AACI's vice president/president-elect. Read More
Jensen Receives Kansas Masonic Foundation Lifetime Achievement Award

Jensen Receives Kansas Masonic Foundation Lifetime Achievement Award

The University of Kansas Cancer Center Roy A. Jensen, MD, vice chancellor and director of The University of Kansas Cancer Center, was awarded the Kansas Masonic Foundation Lifetime Achievement Award. The award has been given to only three other individuals throughout the Kansas Masonic Foundation’s 50-year history. Dr. Jensen is AACI's immediate past president. Read More
AACI Welcomes Koch Institute for Integrative Cancer Research at MIT

AACI Welcomes Koch Institute for Integrative Cancer Research at MIT

This month AACI welcomes the Koch Institute for Integrative Cancer Research at MIT to its membership. Directed by Matthew Vander Heiden, MD, PhD, the Koch Institute focuses on five strategic areas: nanotechnology-based drugs, detection and monitoring, metastasis, precision medicine, and immunology and immunotherapy. With the addition of the Koch Institute, AACI counts all 71 NCI-Designated Cancer Centers among its 104 members. Read More

Grant Renewal to Support Clinical and Translational Research

Vanderbilt-Ingram Cancer Center Vanderbilt University Medical Center has competed successfully for a third renewal of its Clinical and Translational Science Award by the National Institutes of Health. The grant will provide more than $73 million for another five years to support the Vanderbilt Institute for Clinical and Translational Research. Read More
CRI Keynote Spotlight Monique Phillips

CRI Keynote Spotlight: Monique Phillips

Monique Phillips, PMP, will deliver the keynote presentation at the 14th Annual AACI Clinical Research Innovation (CRI) Meeting. Phillips is the People & Business Resource Groups lead of the Black Organization for Leadership and Development at Bristol Myers Squibb. She will be joined by Kimberly Richardson, a patient advocate and ovarian cancer survivor. Phillips and Richardson will discuss implicit bias, straightforward patient communication, and other topics related to optimizing diversit…
More Than 25 Percent of Virginians Unaware of Lifesaving HPV Vaccine

More Than 25 Percent of Virginians Unaware of Lifesaving HPV Vaccine

University of Virginia Cancer Center A study has identified the Virginians least likely to know that there is a vaccine available for human papillomavirus (HPV). More than a quarter of respondents to a survey of state residents had not heard of the vaccine. Those least likely to be aware include males, urban residents, and people who reported lower incomes. Those most likely to know of the vaccine include part-time workers, younger people, and those with higher education. Read M…

Vitamin E Can Boost Immunotherapy Responses by Reinvigorating Dendritic Cells

The University of Texas MD Anderson Cancer Center Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered that vitamin E can enhance immunotherapy responses by stimulating the activity of dendritic cells in the tumor. Read More
Vonderheide Appointed to Second Term as Director

Vonderheide Appointed to Second Term as Director

Abramson Cancer Center of the University of Pennsylvania Robert H. Vonderheide, MD, DPhil, has been appointed to a second five-year term as director of the Abramson Cancer Center. Highlights of his first term include 17 FDA-approved oncology therapies, high-impact basic and translational research discoveries, expansion of radiation oncology services, and development of new methods for live tumor imaging during surgeries. Read More
Break Through Cancer Announces 50 Million in Grants to Support Interdisciplinary Research

Break Through Cancer Announces $50 Million in Grants to Support Interdisciplinary Research

Break Through Cancer will award $50 million in grants to support cutting-edge interdisciplinary research at five top cancer centers. MIT's David H. Koch Professor of Biology Tyler Jacks, PhD, is president of Break Through Cancer. Read More
Senator Roy Blunt and Representative Donald Payne Jr to Receive Cancer Research Ally Award

Senator Roy Blunt and Representative Donald Payne, Jr., to Receive Cancer Research Ally Award

Senator Roy Blunt (R-MO) and Representative Donald Payne, Jr (D-NJ) will be honored with the Cancer Research Ally Award at the 2022 AACI/AACR Hill Day, which will be held virtually on Wednesday, June 15. Both will deliver remarks at 12:00 pm eastern time as part of the event’s lunchtime programming. Read More
Pancreatic Cancer Research Institute Established

Pancreatic Cancer Research Institute Established

Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently established the Sylvester Pancreatic Cancer Research Institute. Nipun Merchant, MD, is the institute's founding director. Read More
Huntsman Recognized for LGBTQ Healthcare Equality by Human Rights Campaign

Huntsman Recognized for LGBTQ+ Healthcare Equality by Human Rights Campaign

Huntsman Cancer Institute at the University of Utah The Human Rights Campaign Foundation has recognized Huntsman Cancer Institute at the University of Utah as an LGBTQ+ Healthcare Equality Leader, awarding it the highest score possible in the 15th anniversary edition of the Healthcare Equality Index. Read More
Riedell to Lead AACI CAR T Steering Committee

Riedell to Lead AACI CAR T Steering Committee

Peter Riedell, MD, assistant professor of medicine at the University of Chicago Medicine Comprehensive Cancer Center, is the new chair of AACI's CAR T Initiative Steering Committee. He succeeds Joseph McGuirk, DO, FACP, whose term expired earlier this year. Read More
Samuel Strober Pioneering Transplantation Immunologist Dies at 81

Samuel Strober, Pioneering Transplantation Immunologist, Dies at 81

Stanford Cancer Institute Samuel Strober, MD, professor of immunology and rheumatology, died in February of multiple myeloma. Focusing on improving transplant recipients’ lives, Dr. Strober developed a way to wean some of these patients from a lifelong regimen of drugs that prevent the immune system from attacking and destroying the donated organ. Read More

Simple Changes in Care Reduced Heart Exposure During Lung Cancer Radiation Treatment

University of Michigan Rogel Cancer Center Radiation to the heart during treatment for locally advanced lung cancer is associated with an increased risk of major adverse cardiac events within the first two years following treatment. The higher the cardiac dose exposure, the higher the risk of a cardiac event. Read More
American Cancer Society Funds Research to Benefit Hispanic Cancer Survivors Caregivers

American Cancer Society Funds Research to Benefit Hispanic Cancer Survivors, Caregivers

The University of Arizona Cancer Center Terry Badger, PhD, RN, a University of Arizona Health Sciences researcher, was one of only four recipients of a $4 million American Cancer Society grant to develop a Cancer Health Equity Research Center with the goal of improving health equity for Hispanic cancer survivors and family caregivers. Read More

Immunotherapy Plus Chemotherapy Before Surgery Improves Lung Cancer Outcomes

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Adding the immunotherapy drug nivolumab to chemotherapy before surgery for patients with operable non-small cell lung cancer reduced the risk of recurrence of the cancer or death by more than one-third, according to results from the Phase III CheckMate-816 trial. It also achieved a nearly twelvefold increase in pathological complete response over patients who received chemotherapy alone. Read More

Lung Cancer Screening Innovation Receives $3.5 Million Grant

Rutgers Cancer Institute of New Jersey With the aid of a $3.5 million grant from the National Institutes of Health, investigators from Rutgers Cancer Institute of New Jersey, along with Holden Cancer Center at the University of Iowa and The University of Texas MD Anderson Cancer Center, are collaborating to address lung cancer screening disparities among individuals with a history of heavy smoking. Read More

SpaceX Takes Experiment to International Space Station

Moffitt Cancer Center Patsy McDonald, PhD, and Derek Duckett, PhD, Moffitt Cancer Center faculty members and founders of CADW Therapeutics, sent a scientific experiment to space in April as a part of Axiom Space’s Axiom Mission 1, the first private astronaut mission to the International Space Station. Read More

Study Reveals Male Sex Hormones Are New Targets for Cancer Immunotherapy

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute A study led by researchers in the Pelotonia Institute for Immuno-Oncology at OSUCCC – James examined the differences in intratumoral immune responses between male and female cancers of non-reproductive origin. Read More

Long-Term Safety of Genetically Modified Immune Effector Cells Shown

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine A new study from researchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital, and Houston Methodist Hospital shows that cancer patients who receive treatment with genetically modified immune cells are not at increased risk for subsequent malignancy when compared to patients who receive standard chemotherapy. Read More

Global Cancer Consortium Studies New Option for Diagnosing Lung Cancer

University of New Mexico Comprehensive Cancer Center Tumor biopsies are currently the most common tool for diagnosing lung cancer. However, according to a new paper published by the University of Kentucky and Manipal Academy of Higher Education, there is evidence that liquid biopsies—obtained from a blood sample—have the potential to replace tumor biopsies that require patients to undergo a surgical procedure. Read More
Plimack Appointed Deputy Director at Fox Chase

Plimack Appointed Deputy Director at Fox Chase

Fox Chase Cancer Center, Temple Health Elizabeth Plimack, MD, MS, chief of the Division of Genitourinary Medical Oncology and professor in the Department of Hematology/Oncology at Fox Chase Cancer Center, has been appointed deputy director. She will oversee the Clinical and Translational Research Plan as she takes on this newly created role. Read More

$3 Million Grant Supports Expansion of Digital Intervention for Skin Self-Examination

Rutgers Cancer Institute of New Jersey With the aid of a $3 million National Cancer Institute grant, Rutgers Cancer Institute of New Jersey researchers aim to enhance the effectiveness of a digital intervention that supports skin self-examination for survivors of melanoma. The project is based on a previous Rutgers Cancer Institute research study that resulted in the development of an internet-based intervention called mySmartSkin. Read More
Kyprianou to Receive American Urological Association Award

Kyprianou to Receive American Urological Association Award

The Tisch Cancer Institute at Mount Sinai Mount Sinai researcher Natasha Kyprianou, MBBS, PhD, a leading expert on prostate, bladder, and kidney cancer, has been awarded the Richard D. Williams, MD, Prostate Cancer Research Excellence Award by the Urology Care Foundation, a nonprofit urological health foundation and official foundation of the American Urological Association. Dr. Kyprianou is the first woman to receive this award. Read More
Ferrell Lands Mark Foundation for Cancer Research Award

Ferrell Lands Mark Foundation for Cancer Research Award

Vanderbilt-Ingram Cancer Center The Mark Foundation for Cancer Research has selected four scientific research projects to receive $12 million in funding for its 2022 Endeavor Awards. Brent Ferrell, MD, is one of the recipients and will work with researchers from the University of Alabama at Birmingham and Fred Hutchinson Cancer Research Center on one of the projects. Read More

$4.7 Million Awarded to Encourage COVID-19 Testing in Underserved Communities and Schools

Huntsman Cancer Institute at the University of Utah University of Utah Health scientists are launching SCALE-UP II and SCALE-UP Counts, a pair of initiatives designed to increase COVID-19 testing and vaccination among rural and underserved populations. Combined, the two initiatives are supported by $4.7 million from the National Institutes of Health. Read More
Study to Gauge Effectiveness of Menthol E Cigarettes as a Quit Smoking Tool

Study to Gauge Effectiveness of Menthol E-Cigarettes as a Quit-Smoking Tool

The University of Kansas Cancer Center Researchers at The University of Kansas Cancer Center, led by Nikki Nollen, PhD, have received a five-year, $3.9 million grant to explore the effectiveness of menthol-flavored versus tobacco-flavored electronic cigarettes in helping smokers stay away from cigarettes and improve their health. The grant is funded by the National Institute on Drug Abuse and the Food and Drug Administration. Read More

Quest for Better Treatments for Rare Blood Cancer Leads to New Therapies

Stanford Cancer Institute Hematologist Jason Gotlib, MD, wanted more effective treatments for patients with systemic mastocytosis. His research has led to the approval of two new treatments by the U.S. Food and Drug Administration. Read More
Vaccine Protects Most Cancer Patients From COVID But Risk Remains Higher for Those With Blood Cancers

Vaccine Protects Most Cancer Patients From COVID, But Risk Remains Higher for Those With Blood Cancers

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Using the nation’s largest COVID-19 data resource, Jing Su, PhD, a researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center found the COVID-19 vaccine protected most cancer patients from getting COVID. However, patients with certain types of cancer have a higher and widely varied risk of breakthrough COVID infections after receiving the vaccine. Read More
Fertig Named to the AIMBE College of Fellows

Fertig Named to the AIMBE College of Fellows

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Elana Fertig, PhD, has been elected by her peers as a fellow of the American Institute for Medical and Biological Engineering (AIMBE), which represents the most accomplished individuals in the fields of medical and biological engineering. The College of Fellows comprises the top two percent of medical and biological engineers in the United States. Read More
Study Finds Marshallese in U S Mobilized to Address Pandemic Hardships

Study Finds Marshallese in U.S. Mobilized to Address Pandemic Hardships

UAMS Winthrop P. Rockefeller Cancer Institute Faced with hardships intensified by the COVID-19 pandemic, Marshallese communities in the United States mobilized to help one another. According to a study by University of Arkansas for Medical Sciences (UAMS) researchers, socially vulnerable groups in the U.S. have experienced food insecurity, housing insecurity, inadequate health care, and difficulty paying bills during the pandemic. Read More

Cancer Repair Mechanism Could Be Potential Drug Target

Duke Cancer Institute, Duke University Medical Center Searching for ways to extend the survival benefit of targeted therapies, a team led by researchers at the Duke Cancer Institute identified a potential new tactic to disrupt the repair mechanism that cancer cells use after treatment, blunting their ability to regenerate. The approach could present a new treatment strategy. Read More
Targeting Cell Clustering by Gene Deletion Reduces Drug Resistance

Targeting Cell Clustering by Gene Deletion Reduces Drug Resistance

Stony Brook Cancer Center A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combating drug resistance when treating microbial infections or cancer. Led by Gábor Balázsi, PhD, the study centers on disassembling cell clusters that can form an added barrier of drug resistance in the disease process. Read More

Stress Receptors Explored as Possible Immune Checkpoint, Suggesting Role for Beta-Blockers in Cancer Treatment

Roswell Park Comprehensive Cancer Center Combining a beta-blocker with the cancer immunotherapy drug pembrolizumab could be a promising new treatment option for many hard-to-treat solid-tumor cancers. Researchers from Roswell Park Comprehensive Cancer Center demonstrated the safety of this treatment combination in patients with advanced or metastatic melanoma in the first prospective clinical trial of this approach. Read More

Artificial Intelligence Helps Physicians Better Assess Bladder Cancer Treatment Effectiveness

University of Michigan Rogel Cancer Center In a small but multi-institutional study, an artificial intelligence-based system improved providers’ assessments of whether patients with bladder cancer had complete response to chemotherapy before a radical cystectomy (bladder removal surgery). Yet the researchers caution that AI isn’t a replacement for human expertise and that their tool shouldn’t be used as such. Read More
Johns Named First Walther Scholar in Psycho Oncology

Johns Named First Walther Scholar in Psycho-Oncology

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indiana University School of Medicine has named Shelley Johns, PsyD, ABPP, the Walther Scholar in Psycho-Oncology. Dr. Johns is the first person to hold this position, which was established by a $14 million gift to IU School of Medicine from the Walther Cancer Foundation to create five endowed positions to develop a supportive oncology program encompassing research and patient care. Read More

Study Reports Racial Disparities for Gastrointestinal Surgery

Yale Cancer Center, Yale School of Medicine African American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according to a large study led by researchers at Yale Cancer Center who examined a cohort of 565,124 adult patients with gastrointestinal cancer undergoing surgery between 2004 and 2017. Read More

Living Donation Opens New Doors for Colorectal Cancer Patients in Need of Liver Transplants

Wilmot Cancer Institute, UR Medicine A recent study demonstrates the first successful living-donor liver transplants in North America for patients who have liver-confined colorectal cancer tumors which cannot be removed by surgery otherwise. The study was conducted across the University of Rochester Medical Center, the University Health Network, and Cleveland Clinic. Read More

Black Patients More Likely to Be Excluded From Pancreatic Cancer Clinical Trials

VCU Massey Comprehensive Cancer Center A recent study conducted by researchers from VCU Massey Cancer Center, the University of Florida College of Medicine and UF Health Cancer Center found that minority patient participation in cancer clinical trials is alarmingly low. Read More

NCI-COG Pediatric MATCH Study Shows Benefit of Genetic Screening in Refractory Tumors

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine To increase access to tumor genetic screening and study the utility of this strategy, the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) partnered to create the NCI-COG Pediatric MATCH trial. Since 2017, more than 1,000 patients have been enrolled in this nationwide protocol, which uses tumor sequencing to find actionable genetic mutations to match patients to 13 different Phase II clinical tr…

Data-Driven Approach to Help Reduce Drug Costs and Treat Diseases

WVU Cancer Institute A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for. David J. Klinke, PhD, leads the research. Read More

Research Reveals Biologically Older Tissue in Patients With Breast Cancer

Yale Cancer Center, Yale School of Medicine An analysis by Yale Cancer Center researchers identified accelerated genetic aging in breast tissue adjacent to breast cancer tumors. Their findings demonstate that adjacent breast tissue is "biologically older" than the chronologic age of the patient, a discovery that may explain why some women develop breast cancer at a younger age and that may also become a future marker of breast cancer risk. Read More
Rivera Named Associate Director for Diversity Equity and Inclusion

Rivera Named Associate Director for Diversity, Equity and Inclusion

Wilmot Cancer Institute, UR Medicine M. Patricia Rivera, MD, has joined the faculty of the University of Rochester Medical Center with several prominent positions, including associate director for Diversity, Equity and Inclusion at Wilmot Cancer Institute. This is the first AD for DEI at Wilmot. She most recently served as professor of medicine at the University of North Carolina, Chapel Hill. Read More

Cummings Named JEDI Director

UCLA Jonsson Comprehensive Cancer Center The UCLA Jonsson Comprehensive Cancer Center has named Amy L. Cummings, MD, its new director for Justice, Equity, Diversity and Inclusion (JEDI). Dr. Cummings is a faculty member in the Department of Medicine, Division of Hematology/Oncology at UCLA David Geffen School of Medicine. Read More

Understanding the Mechanics of Breast Cancer Metastasis

Fred Hutchinson Cancer Center Research at Fred Hutchinson Cancer Research Center in Seattle found that 20 percent of early-stage breast cancer patients will develop metastasis within 20 years of their original diagnosis. While there is no consensus as to why some patients develop "mets" and some don’t, new Fred Hutch research reveals why muscle tissue doesn’t get mets, and how dormant tumor cells in the brain wake up and proliferate. Read More

Prostate Cancer Patients Want Detailed Life Expectancy Information

Cedars-Sinai Cancer Men diagnosed with prostate cancer prefer physicians to explain their life expectancy in quantitative terms—either as a number of years or as a probability of living at a time point—according to a new study by Cedars-Sinai investigators. Life expectancy is a crucial factor in deciding on aggressive treatment like surgery or radiation for prostate cancer. Read More
Zaslow is New Vice President of Payer Strategies

Zaslow is New Vice President of Payer Strategies

Moffitt Cancer Center Evan Zaslow has joined Moffitt Cancer Center as the new vice president of payer strategies, overseeing all aspects of Moffitt’s managed care strategy. Before joining Moffitt, Zaslow served as the chief of the Managed Care Support Branch and contracting officer for the Defense Health Agency. Read More
Breast Surgical Oncologist Joins Cedars Sinai Cancer in Tarzana

Breast Surgical Oncologist Joins Cedars-Sinai Cancer in Tarzana

Cedars-Sinai Cancer Breast surgical oncologist Lauren DeStefano, MD, was recently added the growing roster of cancer specialists at Cedars-Sinai Cancer in Tarzana. She joins Cedars-Sinai Cancer from the University of Washington’s Department of Surgery and the Seattle Cancer Care Alliance. Read More
Beasley Receives ASCI Young Physician Scientist Award

Beasley Receives ASCI Young Physician-Scientist Award

Duke Cancer Institute, Duke University Medical Center Co-leader of the Duke Cancer Institute Melanoma Disease Group Georgia Beasley, MD, MHSc, is among 40 recipients nationally of a Young Physician-Scientist Award from the American Society for Clinical Investigation (ASCI). Read More

Blasting Bladder Cancer

University of New Mexico Comprehensive Cancer Center Neda Hashemi, MD, and her team at UNM Comprehensive Cancer Center are offering several clinical trials, including a National Cancer Institute-sponsored clinical trial that offers people with localized disease the option of surgery—before scars develop—if their cancer does not respond to standard treatment. Read More

Foundation Funds First Distinguished Professorship in Neuroendocrine Tumor Research

UK Markey Cancer Center The University of Kentucky Markey Cancer Foundation received a $1 million gift to create the world’s first distinguished professorship in neuroendocrine tumor research. The Amanda W. Lockey Foundation gives the gift in support of UK Markey Cancer Center medical oncologist Lowell Anthony, MD, a specialist in neuroendocrine tumor treatment. Read More

SKCC, ACS Partnership Honored With Philanthropy Award

Sidney Kimmel Cancer Center at Jefferson Health The Sidney Kimmel Cancer Center at Jefferson Health (SKCC), along with the American Cancer Society (ACS), has been selected as a Faces of Philanthropy honoree by the Philadelphia Business Journal. Read More
Patient Resource an Integral Physician Outreach Tool

Patient Resource: an Integral Physician Outreach Tool

Influence of Patient Resource on referrals Over a 3-year period, one cancer center shares a 12% increase of patient referrals year-over-year With more than 48,000 patients surveyed, 83% state that the personalized guides influence their positive recommendation of cancer center to friends & family For more information, contact Amy Galey.

New AACI Mailing Address

Association of American Cancer Institutes Effectively immediately, all mail for AACI should be directed to: Association of American Cancer Institutes PO Box 7317 Pittsburgh, PA 15213 Read More

Florida Cancer Hospitals Get $100 Million for Research

The UF Health Cancer Center, Sylvester Comprehensive Cancer Center, and Moffitt Cancer Center will receive $100 million for cancer research and treatment in Florida's 2022-2023 spending plan, an increase of about $37 million over the current budget. Read More
Upon His Retirement Modrich Reflects on Career

Upon His Retirement, Modrich Reflects on Career

Duke Cancer Institute, Duke University Medical Center Paul Modrich, PhD, James B. Duke Professor of Biochemistry, professor of chemistry, and member of Duke Cancer Institute, came to Duke in 1976 – when Durham had a small-town feel, the smell of curing tobacco filled the air, and southern accents were the norm. Read More

$25 Million Commitment to Five Cancer Centers Aims to Reduce Cancer Care Disparities

Georgetown Lombardi Comprehensive Cancer Center The Ralph Lauren Corporate Foundation will provide $25 million in new grant funding to expand or establish five Ralph Lauren cancer centers, aimed at reducing disparities in cancer care and access across underserved communities in the United States. The funding will benefit Georgetown Lombardi Comprehensive Cancer Center and Memorial Sloan Kettering (MSK) Ralph Lauren Center, as well as three additional locations that will be confirmed. …
Neel Elected to National Academy of Sciences

Neel Elected to National Academy of Sciences

Laura and Isaac Perlmutter Cancer Center at NYU Langone Benjamin G. Neel, MD, PhD, director of the Laura and Isaac Perlmutter Cancer Center at NYU Langone Health and an internationally renowned expert in cell signaling and cancer biology, has been elected to the National Academy of Sciences. Read More

Major Study Links Breast Cancer Treatment With Increased Risk of Cardiovascular Disease

Fred Hutchinson Cancer Center A new study shows that women receiving certain common therapies for breast cancer may be at increased risk for heart attack, stroke, heart failure, other cardiovascular events, and death. Read More
Lopez Named Associate Director for DEI

Lopez Named Associate Director for DEI

Sidney Kimmel Cancer Center at Jefferson Health Sidney Kimmel Cancer Center at Jefferson Health (SKCC) has appointed Ana Maria Lopez, MD, MPH, MACP, FRCP, as associate director for diversity, equity, and inclusion (DEI). The new leadership role will facilitate and coordinate DEI efforts across the SKCC enterprise. Read More
IT Innovations Capture National Attention

IT Innovations Capture National Attention

Wilmot Cancer Institute, UR Medicine Eric Snyder, director of informatics at the Wilmot Cancer Institute, wants to change the nation’s thinking around information technology in health care. Snyder made headway recently when the biggest professional organization in the field invited him to make three presentations at the Healthcare Information and Management Systems Society 2022 annual meeting. Read More
New Chief of Bone Marrow Transplant and Cellular Therapies Named

New Chief of Bone Marrow Transplant and Cellular Therapies Named

Rutgers Cancer Institute of New Jersey Rutgers Cancer Institute of New Jersey and RWJBarnabas Health have appointed Ira Braunschweig, MD, as chief, Section of Transplant and Cell Therapy at Rutgers Cancer Institute, chief of the Transplant and Cell Therapy Service of the RWJBarnabas Health Oncology service line, and director for Cell Therapy and Bone Marrow Transplantation at Robert Wood Johnson University Hospital, an RWJBarnabas facility. Read More

Nanomedicine Targeting Lymph Nodes Key to Triple-Negative Breast Cancer Treatment

University of Michigan Rogel Cancer Center Research from the University of Michigan Rogel Cancer Center, led by Duxin Sun, PhD, found that targeting the immune microenvironment in lymph nodes and tumors simultaneously led to long-term tumor remission in mice models of metastatic triple negative breast cancer. Further, using nanoparticles to deliver these immune-altering drugs increases treatment efficacy. Read More

Immunotherapy Study Offers Hope for Pancreatic Cancer Patients

Sylvester Comprehensive Cancer Center, University of Miami Researchers at Sylvester Comprehensive Cancer Center in the University of Miami Miller School of Medicine have shown that immunotherapy can be an option for at least one subgroup of pancreatic cancer patients. The study found that patients with inherited BRCA and other similar mutations can achieve complete responses – in some cases going from near death to durable recoveries. Read More

$11.4 Million Grant Renewed to Further Cancer Research

UK Markey Cancer Center The University of Kentucky’s Center for Cancer and Metabolism (CCM) will continue its critical mission to research the metabolism of cancer with a renewed Centers of Biomedical Research Excellence grant award from the National Institutes of General Medical Sciences, part of the National Institutes of Health. The grant—totaling $11.4 million—will continue to fund UK’s CCM over the next five years. Read More
NSABP Foundation Names Rastogi as CEO

NSABP Foundation Names Rastogi as CEO

UPMC Hillman Cancer Center The NSABP (National Surgical Adjuvant Breast and Bowel Project) Foundation has announced that its medical director, Priya Rastogi, MD, will also serve as the chief executive officer of the NSABP effective on July 1, 2022. Read More
Eckhardt Receives Mentorship Award

Eckhardt Receives Mentorship Award

Livestrong Cancer Institutes, The University of Texas at Austin, Dell Medical School S. Gail Eckhardt, MD, is the recipient of the 2022 Hologic Inc. Endowed Women Who Conquer Cancer Mentorship Award from the American Society of Clinical Oncology. Dr. Eckhardt, the inaugural director of the Livestrong Cancer Institutes, is being recognized for her outstanding commitment to the professional development of women in oncology. Read More

Study Illustrates Cost of Cancer Drugs Covered Under Medicare Part D

Vanderbilt-Ingram Cancer Center A new study highlights how some older Americans diagnosed with cancer can face unlimited out-of-pocket spending for prescription drugs under the current structure of the Medicare Part D benefit. The analysis illustrates how the current design of Medicare’s prescription drug benefit program can cost people without subsidies more than $10,000 for one year of treatment. Read More

Researchers Refining Colorectal Cancer Classification

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Analyzing nearly 500,000 single cells, researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center are refining how to classify colorectal cancer and identify new targets to develop effective therapies. Read More
Inaugural Associate Director of DEI Announced

Inaugural Associate Director of DEI Announced

Siteman Cancer Center Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, announces the appointment of Vetta Sanders Thompson, PhD, as its inaugural associate director of diversity, equity, and inclusion (DEI). Read More

DEI, COE Leadership Appointments Announced

Robert H. Lurie Comprehensive Cancer Center of Northwestern University Marquita Lewis-Thames, PhD; June McKoy, MD, MPH, JD, MBA; Jonathan Moreira, MD; and Adam B. Murphy, MD, MBA, MSCI, have been named to new leadership roles within the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. Read More

How Do Patients Feel About Using AI in Health Care?

Yale Cancer Center, Yale School of Medicine New research from Yale Cancer Center provides a new understanding of patients’ views of artificial intelligence (AI) in health care. While comfort level varied by clinical application, most respondents had positive views about AI’s ability to improve care. Concerns surfaced when potential for misdiagnosis, privacy breaches, reduced time with clinicians, and increased costs were discussed. Read More

Genomic Sequencing is Changing Diagnosis, Treatment for Patients With Brain Cancer

UCSF Helen Diller Family Comprehensive Cancer Center Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation, and chemotherapy. But far from suggesting that more treatment always leads to better survival, a new UCSF study shows aggressive therapy is best for this deadly tumor masquerading as lower-grade glioma and underscores the critical role of genomic profiling in diagnosing and grading brain tumors. Read …
Researchers to Examine Obesity Treatment Options With 4 5 Million Grant

Researchers to Examine Obesity Treatment Options With $4.5 Million Grant

The University of Kansas Cancer Center Population health researcher Christie Befort, PhD, received a $4.5 million grant from the National Cancer Institute to fund her work exploring sustainable obesity treatment options for people in rural communities. Dr. Befort’s project, called RE-TOOL, is a five-year randomized controlled trial involving 16 rural clinics and 560 patients. Read More

Partnership to Create First Focused Ultrasound Cancer Immunotherapy Center

University of Virginia Cancer Center UVA Health and the Charlottesville-based Focused Ultrasound Foundation have announced the launch of the Focused Ultrasound Cancer Immunotherapy Center, the world’s first center dedicated specifically to advancing a focused ultrasound and cancer immunotherapy treatment approach that could revolutionize 21st-century cancer care. Read More

UF to Test Novel CAR-Modified T-Cell Technique in Clinical Trial for Glioblastoma

University of Florida Health Cancer Center University of Florida researchers have received approval from the U.S. Food and Drug Administration to test an investigational new therapy in a first-in-human clinical trial for participants with primary glioblastoma. Read More

New Target for CAR T Cells in Solid Tumors Discovered

Moffitt Cancer Center In a new study, Moffitt Cancer Center researchers share the identification of a new potential target for CAR T cells called OR2H1 that they have demonstrated inhibits growth in lung and ovarian tumors. Read More

Innate Immune Cells and Metastatic Cancer

The Jackson Laboratory Cancer Center In a new paper, a team led by Karolina Palucka, MD, PhD, and Jan Martinek, PhD, analyzed patient samples of metastatic melanoma for further insight into how cancer cells are able to escape immune response and grow elsewhere in the body. Read More

Surgical Technique Enables Faster, Fuller Recovery After Radical Prostatectomy

Roswell Park Comprehensive Cancer Center In a new study, Khurshid Guru, MD, and a team of urologic oncology specialists compared the results of radical prostatectomy between 76 men with prostate cancer who chose hydrodissection RARP compared with 126 men who opted for conventional surgical dissection methods. Read More

New Molecular Subset of Pediatric Liver Cancer Identified

University of Virginia Cancer Center New research from Baylor College of Medicine and Texas Children’s Cancer Center characterizes a new molecular type of high-risk pediatric liver cancer. The study showed that these tumors have better outcomes when patients were treated by transplantation, rather than by chemotherapy and surgery alone. Read More

Colon Microbes Provide Clues to Favorable Treatment Options in a Subset of Colon Cancer Patients

Rutgers Cancer Institute of New Jersey Investigators from Rutgers Cancer Institute of New Jersey led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens, including microsatellite-stable and unstable tumors. Read More
Registration Now Open for 2022 AACICCAF Annual Meeting

Registration Now Open for 2022 AACI/CCAF Annual Meeting

Registration is now open for the 2022 AACI/CCAF Annual Meeting, which will take place in person, October 2-4, at InterContinental at the Plaza, Kansas City, MO. This three-day event convenes AACI cancer center members with national cancer research and advocacy groups, industry, and government health agencies to develop solutions to common challenges. Continuing Medical Education (CME) is jointly provided by the American Association for Cancer Research (AACR) and AACI. Read More

Study Found Large Segment of Arkansans Still Susceptible to COVID-19 in Late 2020, 2021

UAMS Winthrop P. Rockefeller Cancer Institute A team of scientists at the University of Arkansas for Medical Sciences (UAMS) carried out an eight-month seroprevalence survey that found 85 percent of the state’s population was still susceptible to the virus in late 2020. Read More
Surgical Oncologist Named Regional Medical Director

Surgical Oncologist Named Regional Medical Director

Cedars-Sinai Cancer Pioneering breast cancer surgeon, clinician, and researcher Armando E. Giuliano, MD—who helped introduce sentinel lymph node biopsy in the early 1990s, sparing many women the need for major breast cancer surgery—has been named regional medical director of the Cedars-Sinai Cancer Breast Oncology Program. Read More
Frosch Wins NCCN Foundation Award

Frosch Wins NCCN Foundation Award

Fox Chase Cancer Center, Temple Health Zachary Frosch, MD, MSHP, a member of the Cancer Prevention and Control research program at Fox Chase Cancer Center, has received a Young Investigator Award from the National Comprehensive Cancer Network and the NCCN Foundation. Read More

Study Identifies New Molecular Target for Cancer Therapy

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Researchers with OSUCCC – James have identified a new molecular drug target that could result in new cancer drugs with fewer side effects. Read More

New Approach to Precision Cancer Treatment Identified

Roswell Park Comprehensive Cancer Center A multidisciplinary team from Roswell Park Comprehensive Cancer Center has uncovered a previously unknown function of a gene that regulates p53, a protein that plays a significant role in more than half of all cancers. Read More

Adolescent, Young Adult Leukemia Survivors Have Shorter Life Span Compared to Those Who Have Never Had Cancer

The University of Texas MD Anderson Cancer Center Researchers at The University of Texas MD Anderson Cancer Center have discovered that adolescent and young adult cancer survivors of acute lymphoblastic leukemia and acute myeloid leukemia have reduced long-term survival rates compared to their peers without cancer. The study also found inferior long-term mortality outcomes persist as far out as three decades into survivorship. Read More
New Hematology Chief and Director of the Wesley Center for Immunotherapy Named

New Hematology Chief and Director of the Wesley Center for Immunotherapy Named

Case Comprehensive Cancer Center Koen van Besien, MD, PhD, will lead the new Wesley Center for Immunotherapy at University Hospitals Seidman Cancer Center as well as the Division of Hematology. He joins UH Seidman Cancer Center from New York-Presbyterian Hospital. Read More

Investigators Receive $1.6 Million for Health Equity Research

Montefiore Einstein Comprehensive Cancer Center Montefiore Einstein Cancer Center has partnered with the Price Family Foundation to fund novel cancer therapies and improving cancer outcomes for historically marginalized communities in the Bronx. The inaugural awards will provide $200,000 in funding over two years to eight teams of basic science, translational, and clinical investigators. Read More

Polypharmacy is Fraught With Risks, Tricky to Navigate

Wilmot Cancer Institute, UR Medicine Even for individuals who do not have cancer, multiple medication use is fraught with risks and tricky to navigate because of the emotions involved, according to Erika Ramsdale, MD, a Wilmot Cancer Institute oncologist, geriatrics specialist, and data scientist who led a recent study on polypharmacy. Read More