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Scientists Named to Influential Researchers List

Siteman Cancer Center Nine research members of Siteman Cancer Center were named to Clarivate’s Highly Cited Researchers list of 2021. The nine, who are faculty members of Washington University School of Medicine in St. Louis, demonstrate significant research influence among their peers. Read More

Improved Treatment Options Found for Patients With Advanced Colorectal Cancer

City of Hope Comprehensive Cancer Center City of Hope has announced study results of a Phase II clinical trial showing monotherapy with sotorasib resulted in anti-tumor activity and a favorable benefit-risk profile among heavily pretreated patients with advanced colorectal cancer. Read More
Greco Inducted as American College of Surgeons Fellow

Greco Inducted as American College of Surgeons Fellow

Fox Chase Cancer Center, Temple Health Stephanie Greco, MD, FACS, an assistant professor in the Department of Surgical Oncology at Fox Chase Cancer Center, became a Fellow of the American College of Surgeons during the convocation ceremony at the ACS Clinical Congress, held virtually in October. Read More
Call for Abstracts 14th Annual AACI CRI Meeting

Call for Abstracts: 14th Annual AACI CRI Meeting

The AACI CRI Steering Committee is currently soliciting abstracts for the 14th Annual AACI CRI Meeting. This year’s meeting theme will focus on innovation in cancer clinical research. The purpose of the abstracts is to inform meeting attendees about clinical trials office challenges and solutions implemented at AACI cancer centers. Read More

Research Contributes to FDA Approval of First-Ever Drug for Acute GVHD

Winship Cancer Institute of Emory University The U.S. Food and Drug Administration (FDA) has approved the first-ever drug to be used for the prevention of acute graft versus host disease (aGVHD) in adult and pediatric patients, opening the door for safer bone marrow and blood stem cell transplants in patients who do not have a perfectly matched graft donor. Read More

Homing in on Shared Network of Cancer Genes

Wilmot Cancer Institute, UR Medicine Wilmot Cancer Institute researchers are a step closer to understanding the complex gene interactions that cause a cell to become malignant. In a new study, the group used network modeling to home in on a set of such interactions that are critical to malignancy, and likely to be fertile ground for broad cancer therapies. Read More

Genetic Mutation Could Play Role in Improving Leukemia Treatment

University of Florida Health Cancer Center In the battle against one type of leukemia, a genetic mutation could hold the key to more effective, lower-dose treatments. The new, early findings by University of Florida Health researchers and their colleagues are especially relevant for older or frail patients who may not be able to tolerate high-dose chemotherapy. Read More
Holcombe Invested as Inaugural J Walter Juckett Chair in Cancer Research

Holcombe Invested as Inaugural J. Walter Juckett Chair in Cancer Research

The University of Vermont Cancer Center With $3 million in support from a longtime donor to the University of Vermont Cancer Center, Director Randall F. Holcombe, MD, MBA, was invested as the inaugural J. Walter Juckett Chair in Cancer Research in the Larner College of Medicine. Read More
Rising Star Reflects on Winding Road to Cancer Disparities Research

Rising Star Reflects on Winding Road to Cancer Disparities Research

VCU Massey Comprehensive Cancer Center  STAT News has named Arnethea Sutton, PhD, as one of this year’s 27 STAT Wunderkinds – the news organization’s award recognizing rising stars in biomedical research. When she arrived at VCU as an undergraduate in 2001, the first in her family to attend college, Dr. Sutton thought she’d be a pharmacist. Then, while earning her bachelor’s degree, she switched to medical laboratory science, working in the pathology lab at VCU Health.   Read More

T-Dxd Analysis Shows Encouraging Results in Controlling Stable Brain Metastases in HER2-Positive Metastatic Breast Cancer

UCLA Jonsson Comprehensive Cancer Center A subgroup analysis of a Phase III study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found consistent progression-free survival and objective response rate benefit when women with HER2-positive metastatic breast cancer were treated with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd), compared to the current standard of treatment. Read More
Skoracki Named Director of Breast Center

Skoracki Named Director of Breast Center

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Roman Skoracki, MD, has been named medical director of the Stefanie Spielman Comprehensive Breast Center (SSCBC) at OSUCCC – James. He succeeds William Farrar, MD, current CEO of The James, who has served as the SSCBC medical director since its inception in 2011. Read More

Research to Examine Racial Disparities in Immunotherapy Effectiveness

Karmanos Cancer Institute, Wayne State University Karmanos Cancer Institute and Wayne State University received a $2,997,215 federal grant to help determine why African Americans show poorer responses than whites to an immune checkpoint inhibitor for metastatic non-small cell lung cancer. Principal investigators are Ann Schwartz, PhD, MPH, deputy center director, and Gerold Bepler, MD, PhD, Karmanos president and CEO. Read More

Venetoclax Combination Therapies Effective Against Challenging Subtypes of AML

The University of Texas MD Anderson Cancer Center Combination therapies including venetoclax and another therapy have displayed promising results against subtypes of acute myeloid leukemia(AML) that are particularly difficult to treat, including relapsed or refractory AML with a specific mutation, high-risk AML, and treated secondary AML. Read More

Study Shows Lymphoma Patients Can Benefit From Receiving CAR T Sooner

Moffitt Cancer Center Results from the ZUMA-7 clinical trial, led by Frederick Locke, MD, vice chair of Moffitt Cancer Center’s Blood and Marrow Transplant and Cellular Immunotherapy Department, show lymphoma patients can benefit from receiving the CAR T product axicabtagene ciloleucel (Yescarta) sooner. Read More

Study Sets Framework for Precision Surveillance of Colorectal Cancer

Vanderbilt-Ingram Cancer Center A team of Vanderbilt researchers has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine. Read More

Colorectal Cancer Screening Lags Among Rural Women, Study Reveals

University of Virginia Cancer Center Women who live in urban and rural areas get screened for breast cancer at similar rates, but rural women get screened for colorectal cancer at significantly lower rates than their urban counterparts, new research reveals. Read More

Research Leads to Unique Clinical Trial of Mesothelioma Treatment

The University of Vermont Cancer Center Since 2004, only two therapies have been approved for the treatment of malignant mesothelioma, which affects about 3,000 people a year in the United States. Now a promising new therapy for mesothelioma and metastatic cancer, arising from laboratory investigations at the University of Vermont, is about to enter a Phase I clinical trial. Read More

Growth Hormone in Colon Found to Play Role in Aging Process

Cedars-Sinai Cancer Investigators at Cedars-Sinai have identified growth hormone in the colon that increases as the colon ages – a discovery that can help guide the development of a new anti-aging therapy. The findings provide important clues on how local non-pituitary growth hormone is activated in aging colon tissue, initiating the first steps in tumor development. Read More

Rogel Earns Rectal Cancer Accreditation

University of Michigan Rogel Cancer Center The University of Michigan Health Rogel Cancer Center has earned a three-year accreditation from the National Accreditation Program for Rectal Cancer, a quality program of the American College of Surgeons’ Commission on Cancer. Read More

Hematologists Present New Research on FLT3 Inhibitors, CART-19

Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center hematology experts in leukemia, lymphoma, and other specialties presented new research at the 63rd annual meeting of the American Society of Hematology. Highlighted projects included research on CAR T cell therapy, immunotherapy, leukemia, lymphoma, and the management of genetic mutations in aggressive and rare blood cancers. Read More

Drug Compound Makes Pancreatic Cancer Cells More Vulnerable to Chemo

Siteman Cancer Center Washington University researchers at Siteman Cancer Center have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy. Studying mice, they found evidence suggesting that the drug also may reduce some of the damaging side effects of the chemotherapy cocktail FOLFIRINOX, commonly used to treat pancreatic cancer. Read More

Leadership Changes to Advance Innovation, Excellence

University of Florida Health Cancer Center The University of Florida Health Cancer Center announces two leadership changes aimed at advancing innovation and excellence in cancer research, care, delivery, and education. In October, Duane Mitchell, MD, PhD, joined the center’s executive leadership team as associate director for innovation and discovery and Elias Sayour, MD, was appointed co-leader of the Cancer Therapeutics & Host Response research program. Read More
Computational Biologist Will Lead Efforts to Integrate Data Science

Computational Biologist Will Lead Efforts to Integrate Data Science

Fred Hutchinson Cancer Center Fred Hutchinson Cancer Research Center has named computational biologist Robert Bradley, PhD, scientific director of the Hutch’s Translational Data Science Integrated Research Center. Dr. Bradley fills the role vacated earlier in 2021 by Raphael Gottardo, PhD, who launched the Translational Data Science IRC in 2018. Read More
The History of the Association of American Cancer Institutes

The History of the Association of American Cancer Institutes

Inspired by the 50th anniversary of the National Cancer Act, AACI is pleased to share The History of the Association of American Cancer Institutes. Written by Donald L. Trump, MD, and Eric T. Rosenthal, authors of Centers of the Cancer Universe: A Half-Century of Progress Against Cancer (Rowman & Littlefield, 2021), the AACI history is based on meeting minutes, other source documents and interviews with AACI past presidents. Read More

COVID-19 Vaccine Effective in People With Cancer, Study Finds

Stanford Cancer Institute The mRNA-based COVID-19 vaccines are effective at preventing infection in most cancer patients, according to a nationwide study of veterans diagnosed with cancer in the past decade. But the researchers found that some vaccinated patients, including those who had received therapies that suppressed their immune systems within six months before vaccination, were less protected than their peers from COVID-19 infection. Read More

Scientists Research New Device to Diagnose Skin Cancer

Huntsman Cancer Institute at the University of Utah Researchers at Huntsman Cancer Institute and the University of Utah have created a device, named URSKIN, that exploits changes in the electrical properties of skin that occur during cancer cell development by using a technique called non-visual electrical impedance demography. Read More

New Tool Shows Prognostic, Clinical Significance of Recently Approved Diagnostic Imaging Modality

UCLA Jonsson Comprehensive Cancer Center Researchers at UCLA Jonsson Comprehensive Cancer Center led a large international study providing what is believed to be the first evidence (albeit indirect) that a recently approved imaging technique improves risk-stratification and long-term prognostic capabilities for patients with high-risk prostate cancer whose conventional imaging showed only localized disease. Read More

How AI and Machine Learning Will Contribute to Cancer Patient Care and Vaccine Design

Rutgers Cancer Institute of New Jersey In a recent viewpoint paper, investigators at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School explored how artificial intelligence and machine learning will complement existing approaches focused on genome-protein sequence information, including identifying mutations in human tumors. Read More

Does Cancer Immunotherapy Work Differently in Men Versus Women?

Sidney Kimmel Cancer Center at Jefferson Health New research shows that women with advanced melanoma are twice as likely as men to die when treated with a combination of the checkpoint inhibitors nivolumab plus ipilimumab. Read More

Social Worker Selected as Emerging Palliative Care Leader

Sidney Kimmel Cancer Center at Jefferson Health Rebecca (Becky) Cammy, LCSW, manager of social work at the Sidney Kimmel Cancer Center at Jefferson Health, has been accepted into the Cambia Health Foundation’s Sojourns Scholar Leadership Program. Cammy is one of 10 emerging interprofessional palliative care leaders carefully chosen through a rigorous selection process from a highly competitive national pool. Read More
Translational Studies Have Potential to Find Lung Cancer Therapies

Translational Studies Have Potential to Find Lung Cancer Therapies

University of Illinois Cancer Center University of Illinois Cancer Center member Jiyeon Kim, PhD, received a four-year grant from the American Cancer Society to investigate whether the pathway that increases fructose and mannose metabolism in lung cancer is a potential therapeutic target. Read More

New Grant Program to Support Community-Led Health Initiatives

VCU Massey Comprehensive Cancer Center The new Massey Cancer Center Community Grant Program will help community partners expand programs focused on the promotion of health, health equity, person-centered care across the cancer continuum—from prevention through survivorship—and reducing suffering from cancer. Read More

Correction - December 2021 AACI Update

Dr. Wendy Brewster is associate director of diversity, equity, and inclusion at UNC Lineberger Comprehensive Cancer Center. A story in the “Leadership Transitions” section of the December 2021 AACI Update misidentified her institution.   Read More

Team Identifies Accelerator of Treatment-Resistant Prostate Cancer

Roswell Park Comprehensive Cancer Center An international research team co-led by scientists at Roswell Park Comprehensive Cancer Center and The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute has identified an important accelerator of treatment-resistant prostate cancer. Read More
Cancer Clinician and Researcher to Serve as Director of GW Cancer Center

Cancer Clinician and Researcher to Serve as Director of GW Cancer Center

The George Washington University (GW) is pleased to announce that Julie E. Bauman, MD, MPH, will join its academic medical enterprise to serve as the director of GW Cancer Center in March 2022. In this role, Bauman will build on the momentum of the last five years to enhance the clinical, research, and academic activities at the cancer center and establish it as the leading provider of cancer care and research in the Washington, DC region. She will also serve as professor of medicine in the GW …
Understanding Catchment Area Coverage to Address Cancer Disparities

Understanding Catchment Area Coverage to Address Cancer Disparities

As part of the presidential initiative of Karen E. Knudsen, MBA, PhD, AACI surveyed its members in 2020 to understand catchment area coverage. Results of the survey were published in a manuscript, "Assessing the Coverage of U.S. Cancer Center Primary Catchment Areas," in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. SKCC Associate Director for Community Integration Amy Leader, PhD, MPH, and Associate Director for Data Science, Chris…
2021 AACI Report Now Available Online

2021 AACI Report Now Available Online

In 2021 AACI continued to take a strong position on the impact of systemic racism and other forms of discrimination in public health. The 2021 AACI Report details the association’s efforts to promote diversity, equity, and inclusion at North America’s leading cancer centers and in our communities, including the introduction of AACI’s Cancer Health Equity Award and AACI President Dr. Caryn Lerman’s presidential initiative focusing on diversifying the cancer leadership pipeline. Read More

New Initiative Aims to Create Shared Data Hub for Cancer Centers

VCU Massey Comprehensive Cancer Center Massey Cancer Center is working with analytics company SAS to power vital research into higher cancer and mortality rates among low-income and vulnerable populations. SAS and Massey will create the Massey Research Analytics Hub, a secure, cloud-based platform with easy-to-use visualizations of quantitative and qualitative data collected from many different sources and systems. Read More
Dolan Named Deputy Director

Dolan Named Deputy Director

The University of Chicago Medicine Comprehensive Cancer Center The University of Chicago Medicine Comprehensive Cancer Center (UCCCC) has appointed M. Eileen Dolan, PhD, as its deputy director. Dr. Dolan has spent the past eight years working as UCCCC’s associate director for cancer research training and education coordination. Previously, she was the long-time co-leader of the center’s Clinical and Experimental Therapeutics Program. Read More
CRI Abstract Submissions Now Open

CRI Abstract Submissions Now Open

The AACI CRI Steering Committee is currently soliciting abstracts for the 14th Annual AACI CRI Meeting. The purpose of the abstracts is to inform meeting attendees about clinical trials office challenges and solutions implemented at AACI cancer centers. The online abstract submission tool is now live. Read More

Land Purchase Approved for New Outpatient Center

UK Markey Cancer Center The University of Kentucky Board of Trustees has approved a purchase agreement for $6.9 million to acquire residential parcels across from UK Albert B. Chandler Hospital for the construction of a new outpatient cancer treatment center and advanced ambulatory complex. Read More

Champion for Cures Nominations Due February 28

AACI cancer center directors are invited to submit nominations for the 2022 Champion for Cures Award by Monday, February 28. The Champion for Cures Award will be presented during the 2022 AACI/CCAF Annual Meeting, October 2-4, at the InterContinental at the Plaza, Kansas City. Read More
Study Receiving CAR T Therapy Sooner Improves Lymphoma Survival

Study: Receiving CAR T Therapy Sooner Improves Lymphoma Survival

The University of Kansas Cancer Center According to a new study co-authored by Joseph McGuirk, DO, a form of chimeric antigen receptor T-cell (CAR T) therapy known by its brand name, Yescarta (axicabtagene ciloleucel), is significantly more effective than the current standard of care in treating people with large B-cell lymphoma (LBCL) who relapse after the first line of treatment. Read More
Addressing High Lung Cancer Rates Among Female Asian Non Smokers

Addressing High Lung Cancer Rates Among Female Asian Non-Smokers

UCSF Helen Diller Family Comprehensive Cancer Center The FANS (Female Asian Never Smokers) Study aims to collect data from Asian American women to shed light on the issue of non-smoking lung cancer, with the hope of identifying new prevention methods and early diagnosis and treatment options. Study investigator and epidemiologist Scarlett Lin Gomez, MPH, PhD, answered questions about the study. Read More

$7.6 Million Gift Launches New Lung Cancer Research Initiative

University of Michigan Rogel Cancer Center Grasping the genetic mutations that drive non-small cell lung cancer has led to new treatments. Yet when a patient is diagnosed with an alteration in the ALK gene, their cancer may become resistant to standard therapy. If that happens, which drug or drugs will they use? A $7.6 million gift from Judith L. Tam and the Richard Tam Foundation has launched an accelerated research initiative at the University of Michigan Health Rogel Cancer Center to …
Encourage Your Legislators to Pass the FY2022 Budget

Encourage Your Legislators to Pass the FY2022 Budget

As of today, the United States government has not passed a Fiscal Year (FY) 2022 budget. The federal government is currently operating with funding through a Continuing Resolution at spending levels for FY2021 until at least February 18. AACI encourages you to ask your legislators to complete the FY2022 budget and to fund the National Cancer Institute at an appropriate level. Read More

Survey Finds Support for Cancer Warnings on Alcohol

University of Virginia Cancer Center Less than half of Americans understand that alcohol consumption increases cancer risk, and a majority of people surveyed say they would support warning labels and drinking guidelines to increase awareness. Read More

Signaling Mechanisms in Pancreatic Cancer Cells That Could Provide Treatment Targets Identified

UCLA Jonsson Comprehensive Cancer Center Research led by scientists at the Jonsson Comprehensive Cancer Center at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers. Read More

MAPK4 Emerges as Novel Therapeutic Target for Triple-Negative Breast Cancer

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly. In a current study, a team at Baylor College of Medicine and collaborating institutions reports that MAPK4 seems to play an important role in triple-negative breast cancer. Read More

Can Prozac Fight Brain Cancer?

Stanford Cancer Institute Pathologist Paul Mischel, MD, and postdoctoral scholar Junfeng Bi, PhD, have discovered that fluoxetine (commonly known as Prozac) appears to target glioblastoma, at least in laboratory mice. Further, real-world data from electronic medical records suggested that glioblastoma patients who were prescribed Prozac along with the standard treatment for the disease survived longer. Read More
Stegh Named Brain Tumor Center Research Director

Stegh Named Brain Tumor Center Research Director

Siteman Cancer Center Alexander H. Stegh, PhD, a leading brain cancer scientist, has been named research director of the Brain Tumor Center at Siteman Cancer Center, which brings together the collective expertise of Washington University subspecialists to provide multidisciplinary care for brain tumor patients. Read More
Kamal is First Chief Patient Officer for ACS

Kamal is First Chief Patient Officer for ACS

Duke Cancer Institute, Duke University Medical Center The American Cancer Society (ACS) has hired Arif Kamal MD, MBA, MHS, FACP, FAAHPM, FASCO, as its first chief patient officer to lead its patient support vision and strategic plans to improve the lives of cancer patients and their families. Read More
Save the Date 2022 AACIAACR Virtual Hill Day

Save the Date: 2022 AACI/AACR Virtual Hill Day

AACI will jointly host its annual Hill Day with the American Association for Cancer Research (AACR) on Wednesday, June 15. The event will be held virtually for the third year. All faculty and staff of AACI cancer centers are invited to spend the day advocating for cancer research funding. Read More

Agreement Announced to Establish Life Sciences Genomic Resource

Vanderbilt-Ingram Cancer Center Nashville Biosciences, a wholly-owned subsidiary of Vanderbilt University Medical Center, has announced an agreement with Illumina, a leading genomic technology company, to realize the full potential of VUMC’s DNA databank, BioVU. Read More
Olopade Recognized for Transformative Breast Cancer Research

Olopade Recognized for Transformative Breast Cancer Research

The University of Chicago Medicine Comprehensive Cancer Center University of Chicago Medicine breast cancer expert Olufunmilayo Olopade, MD, has been named the recipient of this year’s William L. McGuire Award and Lecture, one of the highest honors in breast cancer research, by the San Antonio Breast Cancer Symposium. Read More
Children With Cancer and Other Special Needs Deserve Support During Online Learning

Children With Cancer and Other Special Needs Deserve Support During Online Learning

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University When thousands of schools transitioned to online learning in 2020 due to the COVID-19 pandemic, many children with cancer and other health and education needs, faced significant learning challenges, according to an opinion paper co-authored by Kathy Ruble, PhD, MSN, RN, CRNP, director of the pediatric oncology survivorship clinic at Johns Hopkins Kimmel Cancer Center. Read More

Research Identifies a Key Pathway Fueling Cancer Metastasis

Roswell Park Comprehensive Cancer Center A collaborative research team led by scientists from Roswell Park Comprehensive Cancer Center and Wake Forest University Baptist Medical Center has determined that a small protein, RAC1, actively recruits enzymes involved in nucleotide production to promote cancer metastasis. Read More

$3.15 Million Awarded to Advance Drug Development Platform for Hepatocellular Carcinoma

The Tisch Cancer Institute at Mount Sinai The National Cancer Institute has awarded Mount Sinai researchers Arvin Dar, PhD, Ernesto Guccione, PhD, and Amaia Lujambio, PhD, $3.15 million in grant funding to assess the potential of a multidisciplinary drug development platform to identify new biological targets for precision-based therapeutics for hepatocellular carcinoma. The platform includes precision mouse models, tumor 3D organoids, and a proprietary library of small molecule inhibito…
Market Differentiator Patient Resource Navigator

Market Differentiator: Patient Resource Navigator

Of more than 85,000 patients surveyed: Improves outcomes: 95% state the guides assist them in following their doctor’s treatment plan Increases market share: 90% report the guides will influence their recommendation of cancer center Ensures educational equity: 94% found the guides comprehensive & easy to read For more information, contact Amy Galey. Learn More
Flores Named Associate Center Director of Basic Science

Flores Named Associate Center Director of Basic Science

Moffitt Cancer Center Elsa R. Flores, PhD, has been named Moffitt Cancer Center’s associate center director of basic science. In her new role, Dr. Flores will oversee the Basic Science Division, which includes the Cancer Physiology, Drug Discovery, Immunology, Molecular Oncology, and Tumor Biology departments. Read More
Malik Honored by American Thoracic Society

Malik Honored by American Thoracic Society

University of Illinois Cancer Center University of Illinois Cancer Center member Asrar Malik, PhD, was awarded the 2021 Solbert Permutt Trailblazer Award in Pulmonary Physiology and Medicine by the American Thoracic Society. He was nominated for his commitment to mentorship and pioneering work in endothelial and immune cells. Read More

Targeted Two-Drug Therapy Effective to Treat Advanced Cervical Cancer

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute The combination of two novel immune therapy agents could be an effective new treatment option for women facing recurrent or advanced cervical cancer, according to the results of a multicenter Phase II clinical trial led by researchers at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute. Read More

Genetic and Lifestyle Calculator Reveals Which Younger Adults Are Most at Risk of Colorectal Cancer

Laura and Isaac Perlmutter Cancer Center at NYU Langone A new risk score can identify men and women under age 50 most likely to develop a cancer of the colon or rectum, an international study shows. The score, a number between 0 and 1, is made from a calculation of people’s risk of developing cancers in either digestive tract organ based on 141 genetic variants more common in people with the disease. Read More

Colorectal Cancer Screening Lagging Among Rural Women

University of Virginia Cancer Center Women who live in urban and rural areas get screened for breast cancer at similar rates, but rural women get screened for colorectal cancer at significantly lower rates than their urban counterparts, new research reveals. Read More
Lucas Named Chief Community Impact Officer

Lucas Named Chief Community Impact Officer

Wilmot Cancer Institute, UR Medicine Candice Lucas, EdD, MBA, has been named Wilmot Cancer Institute’s first chief community impact officer. The position is located within the Community Outreach and Engagement Office with a goal of ensuring the community’s diverse voices are embedded in Wilmot programs, research, and clinical practices. Read More

Two Antibodies Synergize in Triple Whammy to Pediatric Cancers, Study Finds

Stanford Cancer Institute A combination of anti-cancer antibodies produced a powerfully synergistic response in two hard-to-treat pediatric cancers, according to a new study in mice, led by researchers at the Stanford University School of Medicine. Read More

Study Shows How Ovarian Cancer Starts in High-Risk Women

Cedars-Sinai Cancer Some women with BRCA-1 mutations choose to have their breasts or ovaries and fallopian tubes surgically removed even though they may never develop cancers in these tissues. Findings from a new study could help pinpoint which of these women are most likely to develop ovarian cancer in the future—and which are not—and pursue new ways to block the process or treat the cancer. Read More

Genetic Score Developed to Improve Pediatric Cancer Treatments

University of Florida Health Cancer Center University of Florida researchers have developed a new genomics-based score to deliver more personalized and effective chemotherapy treatments to pediatric leukemia patients. The predictive score brings a precision medicine approach to treating childhood acute myeloid leukemia. Read More

Cancer-Immu Data Portal Launched for Predicting Response to Immune Checkpoint Blockade Immunotherapy

Vanderbilt-Ingram Cancer Center A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors. Read More

Blood Test Helps Predict Who May Benefit From Lung Cancer Screening

The University of Texas MD Anderson Cancer Center A blood test, combined with a risk model based on an individual’s history, more accurately determines who is likely to benefit from lung cancer screening than the current U.S. recommendation, according to a study led by researchers from The University of Texas MD Anderson Cancer Center. Read More

Two New Leaders Named to Enhance Patient Care

University of Michigan Rogel Cancer Center The University of Michigan Health Rogel Cancer Center has named David C. Smith, MD, chief medical officer and associate director for cancer clinical services, and Shruti Jolly, MD, associate director for the Michigan Medicine statewide cancer network. Read More
Sampson Joins UNM Cancer Center as Clinical Research Administrator

Sampson Joins UNM Cancer Center as Clinical Research Administrator

University of New Mexico Comprehensive Cancer Center Cheryl Sampson, MBA, has joined the Clinical Research Office at the UNM Comprehensive Cancer Center. She brings more than 20 years of experience in clinical research program administration and has assumed increasing responsibilities over her career. Read More

Physicians Receive ACS Awards

UMMC Cancer Center and Research Institute Two University of Mississippi Medical Center physicians have been honored by the American Cancer Society for partnering with the nonprofit in preventing and detecting cancer. Pierre de Delva, MD, is the ACS South Region 2021 Cancer Control Partner of the Year. William Robinson, MD, is the 2021 Get Screened Champion of the Year. Read More

Study Details Chromosome-Level Changes That Allow Melanomas to Develop Drug Resistance

UCLA Jonsson Comprehensive Cancer Center To investigate mutations in a key cancer-promoting genetic pathway, UCLA Jonsson Comprehensive Cancer Center researchers led the development of a melanoma model of drug resistance, enabling them to study structures and dynamics resulting in intrachromosomal and extrachromosomal changes that support resistance in cancer cells. Read More

New Hope for Patients With Relapsed Large B-cell Lymphoma

University of Colorado Cancer Center Over the past four years, Manali Kamdar, MD, has been the lead investigator on a global, multicenter, Phase III clinical study that shows that Breyanzi (lisocabtagene maraleucel; liso-cel), a CAR T-cell drug, can improve outcomes for patients with large B-cell lymphoma. Read More

New Color-Coded Test Quickly Reveals if Medical Nanoparticles Deliver Their Payload

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Johns Hopkins Medicine researchers have developed a color-coded test that quickly signals whether newly developed nanoparticles—ultra small compartments designed to ferry medicines, vaccines and other therapies—deliver their cargo into target cells. Read More

New Program Leadership

University of Colorado Cancer Center The University of Colorado Cancer Center is pleased to announce several leadership transitions. Patricia Ernst, PhD, will join Tin Tin Su, PhD, as co-leader of the Molecular and Cellular Oncology Program, a position most recently held by Craig Jordan, PhD. Stacy Fischer, MD, will join Jamie Studts, PhD, and Rajesh Agarwal, PhD, to co-lead the Cancer Prevention and Control Program. Read More

Jenkins, Kovak Appointed to New Leadership Positions

UAMS Winthrop P. Rockefeller Cancer Institute Amy Jo Jenkins, MS, CCRP, has been named associate director of administration for the UAMS Winthrop P. Rockefeller Cancer Institute. Succeeding Jenkins, Matthew Kovak, MS, CCRP, has been promoted to executive director of the clinical trials office. Read More

VA Data Analyzed to Study Prostate Cancer Disparities

Moffitt Cancer Center Moffitt Cancer Center has been conducting research on disparities in prostate cancer, specifically evaluating the interplay between social and biological mechanisms that drive the disease among different races and ethnicities. Its newest study is a collaboration with the Prostate Cancer Foundation, the U.S. Department of Veterans Affairs, and John and Daria Barry Foundation Precision Oncology Center of Excellence. Read More

Sensitivity to Chemotherapy May Guide Treatment of Patients With Stomach Cancer

Roswell Park Comprehensive Cancer Center A study led by scientists at Roswell Park Comprehensive Cancer Center shows that chemotherapy after surgery for gastric adenocarcinoma is significantly associated with longer survival in patients with chemosensitive disease, but not in those with very sensitive or refractory disease. Read More
Researchers Pilot Device for Earlier Ovarian Cancer Detection

Researchers Pilot Device for Earlier Ovarian Cancer Detection

The University of Arizona Cancer Center University of Arizona Cancer Center Member Jennifer Barton, MD, has spent nearly a decade developing a falloposcope to detect ovarian cancer in its early stages. John Heusinkveld, MD, has now used the device to capture images of study participants' fallopian tubes for the first time. Read More

Novel Compound Doubles Mean Survival in Pre-Clinical Study

University of Illinois Cancer Center Researchers from the University of Illinois Cancer Center have developed a compound that more than doubles mean survival time in animal models of pancreatic cancer. Survival time was further extended when immune therapy was added. Read More
New Chair of Hematology Oncology and Palliative Care Named

New Chair of Hematology, Oncology and Palliative Care Named

VCU Massey Comprehensive Cancer Center On March 1, Renato G. Martins, MD, MPH, will become the new chair of hematology, oncology and palliative care at VCU Massey Cancer Center and the Department of Internal Medicine at the VCU School of Medicine. Read More
Inaugural Director of Center for Blood Cancers Appointed

Inaugural Director of Center for Blood Cancers Appointed

Laura and Isaac Perlmutter Cancer Center at NYU Langone Faith E. Davies, MD, has been appointed the inaugural director of the Center for Blood Cancers at NYU Langone Health’s Perlmutter Cancer Center. Dr. Davies currently serves as professor in the Department of Medicine at NYU Grossman School of Medicine and director of the Clinical Myeloma Program at Perlmutter. Read More
Farma Elected to Leadership Position in the Society of University Surgeons

Farma Elected to Leadership Position in the Society of University Surgeons

Fox Chase Cancer Center, Temple Health Jeffrey M. Farma, MD, FACS, chief of the Division of General Surgery and co-director of the Melanoma and Skin Cancer Program at Fox Chase Cancer Center, has been elected a member-at-large for the Society of University Surgeons. Read More

Fully Vaccinated Cancer Patients Who Had Breakthrough COVID-19 Show 13 Percent Mortality Rate

Vanderbilt-Ingram Cancer Center The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained at high risk for hospitalization and death. Fully vaccinated patients who experienced breakthrough infections had a hospitalization rate of 65 percent, an ICU or mechanical ventilation rate of 19 percent, and a 13 percent death rate. Read More
Uy Named Leukemia Committee Co chair of Clinical Trials Group

Uy Named Leukemia Committee Co-chair of Clinical Trials Group

Siteman Cancer Center Geoffrey L. Uy, MD, a Washington University physician at Siteman Cancer Center, has been named co-chair of the Leukemia Committee of the Alliance for Clinical Trials in Oncology. Read More

Study Shows How Changing Gut Microbiota Can Affect Lupus Disease Activity in Mice

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Research led by The Ohio State University Wexner Medical Center and College of Medicine found that introducing a single bacterium called segmented filamentous bacteria to the gut microbiota causes detrimental effects on lupus nephritis in mice. Read More

Sorting Cancers by Immune Archetypes May Offer New Approach for Precision Immunotherapies

UCSF Helen Diller Family Comprehensive Cancer Center Using data from over 300 patient tumors, UC San Francisco researchers have described 12 classes of "immune archetypes" to classify cancer tumors. Their findings reveal that cancers from different parts of the body are immunologically similar to one another. These classifications can enhance each patient’s choice of cancer immunotherapies. Read More

Surgeon-Scientist Tapped as Chair of Department of Neurosurgery

Duke Cancer Institute, Duke University Medical Center Gerald Arthur Grant, MD, an internationally known surgeon-scientist, has been named the new chair of the Department of Neurosurgery at Duke University School of Medicine, effective April 1. Dr. Grant returns to Duke from Stanford University. Read More

Clinical Trials Office Medical Director Appointed

Cedars-Sinai Cancer Bobbie J. Rimel, MD, has been appointed medical director for the Cancer Clinical Trials Office (CCTO) at Cedars-Sinai Cancer. Dr. Rimel’s research has focused on clinical trial accrual, recruitment and informed consent. As CCTO medical director she will provide guidance and leadership to ensure the quality of services. Read More
Park Named New Director of VICC

Park Named New Director of VICC

Ben Ho Park, MD, PhD, Cornelius Abernathy Craig Professor of Medicine, and deputy director of the Vanderbilt-Ingram Cancer Center (VICC), has been named the center’s new director. Park will begin serving in this role on July 1, when he succeeds longtime VICC director Jennifer Pietenpol, PhD, who is assuming a new leadership role with Vanderbilt University Medical Center. Read More
Register Now for PCLI Career Development Webinar

Register Now for PCLI Career Development Webinar

The AACI Physician Clinical Leadership Initiative (PCLI) will host "Career Development: Making the Transition From Training to Clinician Investigator" at 1:00 pm eastern time on Wednesday, March 9. The panel includes physicians who have achieved success in launching clinical research early in their careers who will provide examples of challenges and solutions as well as early career and transition advice. Read More
Thompson to Step Down

Thompson to Step Down

Memorial Sloan Kettering Cancer Center Craig B. Thompson, MD, has announced his intention to step down as president and chief executive officer of Memorial Sloan Kettering Cancer Center. Dr. Thompson will continue in his role until the Boards of Trustees and Governing Trustees identify his successor. Read More

Largest Publicly Shared Gift for Liver Research Announced

VCU Massey Comprehensive Cancer Center Virginia Commonwealth University will radically expand treatment options for liver and liver-related metabolic diseases thanks to a historic $104 million gift from Richard Todd Stravitz, MD, and his family’s Barbara Brunckhorst Foundation. Read More
Op Ed Ending Cancer As We Know It

Op-Ed: Ending Cancer As We Know It

On February 17, an opinion piece co-authored by AACI President Caryn Lerman, PhD, and Vice President/President-elect Robert A. Winn, MD, appeared on TheHill.com. In "Ending Cancer As We Know It," Drs. Lerman and Winn described the progress made in cancer research since the National Cancer Act was signed into law in 1971. They also called for Congress to invest in cancer research to support President Biden's renewed commitment to the Cancer Moonshot. Read the Op-Ed
Oncologist Shares His Own Cancer Experiences in Podcast

Oncologist Shares His Own Cancer Experiences in Podcast

Laura and Isaac Perlmutter Cancer Center at NYU Langone When Abraham Chachoua, MD, walks into a patient’s room, he stays for a while. His patients are an extension of his family, and he loves to tell funny stories about his life and make them laugh. "Being a doctor is more than just prescribing medication," says Dr. Chachoua, who learned this lesson early on. Read More
Drug Combination Trial Shows Promising Results in Treatment of Colorectal Cancer

Drug Combination Trial Shows Promising Results in Treatment of Colorectal Cancer

The University of Kansas Cancer Center A Phase II study led by Anwaar Saeed, MD, and investigators at The University of Kansas Cancer Center shows promising efficacy in people with metastatic colorectal cancer who have tried standard systemic chemotherapy, but it did not work. Read More