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Pietenpol Named Chief Scientific and Strategy Officer

Pietenpol Named Chief Scientific and Strategy Officer

Vanderbilt-Ingram Cancer Center Jennifer Pietenpol, PhD, director of the Vanderbilt-Ingram Cancer Center, is stepping down on June 30 to focus on a combined leadership role for Vanderbilt University Medical Center as chief scientific and strategy officer. Read More
Mark Foundation Appoints Du Bois Executive Chairman

Mark Foundation Appoints DuBois Executive Chairman

Hollings Cancer Center, Medical University of South Carolina Raymond N. (Ray) DuBois, MD, PhD, will join the Mark Foundation for Cancer Research as executive chairman of the board. He will assume his role at the Mark Foundation in addition to his current role as director of MUSC Hollings Cancer Center and Distinguished University Professor at Medical University of South Carolina (MUSC). Read More
AACI Applauds President Bidens Revamped Moonshot

AACI Applauds President Biden's Revamped Moonshot

Last month President Joe Biden announced a relaunch of the White House Cancer Moonshot. To implement the plan, the administration will convene a "cancer cabinet" of government officials with the goal of cutting the cancer death rate in half within 25 years. Pictured, President Biden and AACI Executive Director Jennifer W. Pegher at the White House, February 2, 2022. Read More
Reminder CRI Abstract Deadline is March 14

Reminder: CRI Abstract Deadline is March 14

The AACI CRI Steering Committee is currently soliciting abstracts for the 14th Annual AACI CRI Meeting. This year’s meeting theme will focus on innovation in cancer clinical research. The deadline to submit an abstract is 5:00 pm Pacific time on Monday, March 14. Read More

Join AACI to Advocate for Cancer Research Funding

AACI will jointly host its annual Hill Day with the American Association for Cancer Research (AACR) on Wednesday, June 15. All faculty and staff of AACI cancer centers are invited to spend the day advocating for a strong federal investment in biomedical research—and cancer research in particular—through the NIH and the NCI. Registration for the virtual Hill Day will open in April. In the meantime, we encourage AACI members to contact your legislators and urge them to pass the FY 2022 budget and…

More Than $15.6 Million Received in CPRIT Funding

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Researchers with the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine have been awarded more than $15.6 million in grants by the Cancer Prevention & Research Institute of Texas (CPRIT) to support cancer research, treatment, and prevention for underserved populations. Read More

Clinical Research Center Celebrates Decade of Investigational Science

The University of Kansas Cancer Center Ten years ago, the University of Kansas Clinical Research Center opened its doors. The facility looked like a building in a suburban office park, not a place where science could change lives. But looks can be deceiving. Read More

International Colorectal Cancer Study Receives $10 Million

Huntsman Cancer Institute at the University of Utah An international study of colorectal cancer called the ColoCare study has received a five-year renewal and $10 million to fuel new innovations in colorectal cancer treatment. This next phase of the project will focus on developing new medical interventions based on earlier research findings from the ColoCare study. Read More
Fleisher Receives Lifetime Achievement Award

Fleisher Receives Lifetime Achievement Award

Fox Chase Cancer Center, Temple Health Linda Fleisher, PhD, MPH, associate research professor in the Cancer Prevention and Control research program at Fox Chase Cancer Center, was recently recognized with the Lillie D. Shockney Lifetime Achievement Award from the Academy of Oncology Nurse & Patient Navigators. Read More
Patient Resource Assists With Retaining and Acquiring New Cancer Patients

Patient Resource Assists With Retaining and Acquiring New Cancer Patients

"After implementing Patient Resource Guides, 60 percent of patients who came from other cancer programs for a second opinion selected our center to receive their care." - Mark S. Roh, MD, Former President of the University of Florida Health Cancer Center Orlando Health (now Orlando Health Cancer Institute) For more information, contact Amy Galey. Learn More

With Personalized Medicine, a Shelved Cancer Drug Could Get Another Shot

VCU Massey Comprehensive Cancer Center A study by VCU Massey Cancer Center researchers shows that triplatin is effective against triple negative breast cancer. Triplatin, a 30-year-old drug, has faced a bumpy road on the path to Food and Drug Administration approval, but this study offers a new insight that could finally help to get it over the finish line. Read More
Director Named for Phase I Clinical Trials and Investigational Therapeutics

Director Named for Phase I Clinical Trials and Investigational Therapeutics

Rutgers Cancer Institute of New Jersey Rutgers Cancer Institute of New Jersey has named Sanjay Goel, MD, MS, as director of its Phase I/Investigational Therapeutics Program. He is also a professor of medicine at Rutgers Robert Wood Johnson Medical School. Read More

Genome Study Finds Unexpected Variation in Fundamental RNA Gene

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers, directed by Marikki Laiho, MD, PhD, looking for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist. Read More
Opyrchal Named Inaugural Chair in Breast Cancer Discovery

Opyrchal Named Inaugural Chair in Breast Cancer Discovery

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Mateusz Opyrchal, MD, PhD, is the inaugural Vera Bradley Foundation Chair in Breast Cancer Discovery in the Vera Bradley Foundation Center for Breast Cancer Research at the IU Simon Comprehensive Cancer Center. He will also co-lead the cancer center’s Experimental and Development Therapeutics research program and direct the solid tumor Phase I program. Read More
Incoming AUA President Continuing Leadership Tradition

Incoming AUA President Continuing Leadership Tradition

Wilmot Cancer Institute, UR Medicine When Edward Messing, MD, FACS, assumes the American Urological Association (AUA) presidency in May 2022, he will follow in the footsteps of other leaders in the field from the University of Rochester Medical Center. Read More
Chinnaiyan Awarded Sjoberg Prize

Chinnaiyan Awarded Sjoberg Prize

University of Michigan Rogel Cancer Center Arul M. Chinnaiyan, MD, PhD, was awarded the 2022 Sjöberg Prize by the Royal Swedish Academy of Sciences, which also awards Nobel Prizes. He is being honored for the discovery of recurrent gene fusions in prostate cancer. Read More

Sequencing Study Unlocks Mystery of Multiple Myeloma

Roswell Park Comprehensive Cancer Center Using advanced cell sequencing technology and state-of-the-art imaging techniques, researchers at Roswell Park Comprehensive Cancer Center have provided a molecular and biological explanation for multiple myeloma, discovering that different myeloma clones can be present in a single patient. Read More
New Brain Metastases Guidelines to Improve Care Patient Survival

New Brain Metastases Guidelines to Improve Care, Patient Survival

University of Virginia Cancer Center New guidelines for treating cancers that have spread to the brain are poised to improve care for patients and help many live longer, better lives. The new guidelines come from an expert panel assembled by the American Society of Clinical Oncology, including UVA Cancer Center’s David Schiff, MD. Read More
Cancer Clinical Trials Office Welcomes New Medical Director

Cancer Clinical Trials Office Welcomes New Medical Director

University of Colorado Cancer Center Marie Wood, MD, has been named the medical director of the cancer clinical trials office at the University of Colorado Cancer Center. She completed medical school and fellowship training at the University of Colorado School of Medicine and returns to Colorado from the University of Vermont Cancer Center. Read More
Associate Director of Womens Cancers Named

Associate Director of Women's Cancers Named

The Tisch Cancer Institute at Mount Sinai Stephanie Blank, MD, has been named associate director of women’s cancers for The Tisch Cancer Institute at Mount Sinai. In this role, Dr. Blank will be instrumental in encouraging translational research for women’s cancers. Read More

Cardio-Oncology Recognized for Excellence

Siteman Cancer Center The Washington University Cardio-Oncology Center at Siteman Cancer Center has been recognized by a leading international group. The center received designation as a Center of Excellence at the highest level, Gold, after a recent review by the International Cardio-Oncology Society. Read More

Study: Antibody Response Varies by Tumor Type and Treatment

Cedars-Sinai Cancer Dual studies by Cedars-Sinai Cancer researchers have found significant differences in the durability of antibody responses and frequency of breakthrough cases in patients who are undergoing cancer treatments and receive certain COVID-19 vaccinations. They also found that adverse symptoms experienced after vaccination varied by tumor type and treatment. Read More

High Levels of PFAS Found in Anti-Fogging Sprays and Cloths

Duke Cancer Institute, Duke University Medical Center The anti-fogging sprays and cloths many people use to prevent condensation on their eyeglasses when wearing a mask or face shield may contain high levels of per- and polyfluorinated alkyl substances (PFAS), a new Duke University-led study finds. Read More

Stem Cell Discoveries Hold Potential to Improve Cancer Treatment

Cedars-Sinai Cancer Two recent discoveries by stem cell scientists at Cedars-Sinai may help make cancer treatment more efficient and shorten the time it takes for people to recover from radiation and chemotherapy. Read More

Immunotherapy Before Liver Cancer Surgery Can Kill Tumor, and Likely Residual Cancer Cells

The Tisch Cancer Institute at Mount Sinai Immunotherapy given before surgery caused liver cancer tumors to die off in one-third of the patients enrolled in a first-of-its-kind clinical trial, Mount Sinai researchers report. The Phase II trial results suggested that the neoadjuvant immunotherapy may kill not only the tumor, but also microscopic cancer cells that surgery would miss. Read More

Prior Treatment With Cancer Drug Likely Renders COVID-19 Vaccine Ineffective

Stanford Cancer Institute People who have been treated with the cancer drug rituximab, or similar drugs, respond poorly or not at all to subsequent COVID-19 mRNA vaccines, according to a study by researchers at Stanford Medicine. In contrast, vaccination immediately prior to such treatments can generate a months-long, durable antibody response, the study found. Read More

Membranes Help Researchers Capture Tiny, Telltale Vesicles

Wilmot Cancer Institute, UR Medicine Researchers from the University of Rochester and University of Chicago teamed up for one of the first known projects to successfully isolate and study extracellular vesicles (EVs). They adapted nanomembranes from the lab of James McGrath, PhD, in a microfluidic cross-flow filtration system to capture and study individual EVs. Read More

COVID-19 Vaccine Hesitancy Prevalent Even Among Vaccinated

UAMS Winthrop P. Rockefeller Cancer Institute Researchers with the University of Arkansas for Medical Sciences (UAMS) Office of Community Health and Research recently published four articles on a study they conducted that found that many adults in Arkansas receiving the COVID-19 vaccine are doing so despite experiencing some doubts about the shot. Read More

Novel Transplant Approach Improves Odds for Leukemia Patients

Fred Hutchinson Cancer Center In the latest and largest study yet of a novel technique for treating leukemia patients, researchers have affirmed that it dramatically reduces chronic graft vs. host disease in those receiving blood stem cell transplants. Read More
Gehrig to Chair Obstetrics and Gynecology

Gehrig to Chair Obstetrics and Gynecology

University of Virginia Cancer Center Paola A. Gehrig, MD, has been appointed chair of the Department of Obstetrics and Gynecology at the University of Virginia School of Medicine. She joins UVA from the University of North Carolina at Chapel Hill and serves as principal investigator on a National Cancer Institute grant to study ovarian cancer. Read More

Cancer Consortium Announces New Leadership

Fred Hutchinson Cancer Center Mignon Loh, MD, and Elizabeth M. Swisher, MD, have been appointed deputy directors of the Fred Hutch/University of Washington Cancer Consortium. They replace Nancy E. Davidson, MD, who will continue as senior vice president and director of Fred Hutch’s clinical research division, president and executive director of Seattle Cancer Care Alliance, and chief of medical oncology at University of Washington. Read More

Study Explores New Path to Treat Advanced Triple-Negative Breast Cancer

Yale Cancer Center, Yale School of Medicine A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing. The discovery is an early step in finding new therapeutics for triple-negative breast cancer. Read More

Researchers Make New Findings About How to Test Cancer-Fighting Drugs

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Researchers from Indiana University School of Medicine are discovering new ways to find out how effective a drug might be against cancer. Their findings are detailed in a paper that "completely changes the way we need to collect tumor tissues and test for drug sensitivity," said Harikrishna Nakshatri, PhD, a senior author of the paper. Read More

Fungal Pathway Leads Researchers to New Treatment Target for Pancreatic Cancer

Roswell Park Comprehensive Cancer Center Scientists at Roswell Park Comprehensive Cancer Center have identified a potential new target for the treatment of pancreatic cancer. The study outlines the team’s discovery of a fungus-activated pathway that fuels the production of a molecule present in cancerous cells in the pancreas. Read More
Nguyen Named Associate Director for DEI

Nguyen Named Associate Director for DEI

UCSF Helen Diller Family Comprehensive Cancer Center Tung Nguyen, MD, has been named associate director for diversity, equity, and inclusion (DEI) for the UCSF Helen Diller Family Comprehensive Cancer Center. Dr. Nguyen will lead the cancer center's ongoing efforts to build and train a workforce that is diverse, inclusive, and equitable. Read More
Messersmith Named CMO of Oncology Services

Messersmith Named CMO of Oncology Services

University of Colorado Cancer Center University of Colorado (CU) Cancer Center leader Wells Messersmith, MD, has been named chief medical officer of oncology services at UCHealth. He will oversee cancer care at all UCHealth locations with a focus on expanding advanced treatments and the clinical trials UCHealth offers in partnership with the CU Cancer Center. Read More

Researchers Named Young Investigator Award Winners

Yale Cancer Center, Yale School of Medicine Yale Cancer Center is pleased to announce four 2021 Young Investigator Award winners selected by the American Journal of Hematology (AJH). The winners were selected among the manuscripts published in AJH on the basis of the scientific quality and originality of the work. Read More

Immersion Science Program Directors Win Education Award

Fox Chase Cancer Center, Temple Health The two leaders of the Immersion Science Program at Fox Chase Cancer Center, which allows students to explore science in a hands-on way while also providing valuable data to researchers, have received the Elizabeth W. Jones Award for Excellence in Education from the Genetics Society of America. Read More

Trametinib is Potential New Standard-of-Care for Recurrent Low-Grade Serous Ovarian Carcinoma

The University of Texas MD Anderson Cancer Center A study led by researchers at The University of Texas MD Anderson Cancer Center reported that the MEK inhibitor trametinib reduced the risk of disease progression or death by 52 percent compared to standard-of-care therapies for the treatment of low-grade serous ovarian carcinoma. Read More

Rural Residents Perceive More Cancer-Related Information Overload Than Urban Residents

Huntsman Cancer Institute at the University of Utah Compared to U.S. urban adults, rural adults were more likely to think fatalistically about cancer and feel overwhelmed by information about cancer prevention, according to recently published results. Read More

Immune Cells Leave 'Fingerprints' on Tumors Metastasized to the Brain

UCSF Helen Diller Family Comprehensive Cancer Center Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across seven different types of brain tumors, each containing both immune and non-immune cell types. Read More
Oncologist Advances Innovative Clinical Trials for Breast Cancer

Oncologist Advances Innovative Clinical Trials for Breast Cancer

Laura and Isaac Perlmutter Cancer Center at NYU Langone Nancy Chan, MD, a medical oncologist who treats people with breast cancer, joined NYU Langone Health’s Perlmutter Cancer Center in September 2021 after spending seven years at Rutgers Cancer Institute as the co-leader of breast oncology. Read More

New Chief Clinical Operating Officer Named

City of Hope Comprehensive Cancer Center Vince Jensen has been appointed chief clinical operating officer for City of Hope. He will lead clinical operations on the institution’s main campus, as well as throughout its network of care locations in Southern California. Read More

Siteman Reaccredited for Radiation Oncology

Siteman Cancer Center The American Society for Radiation Oncology (ASTRO) has reaccredited the radiation oncology practice at Siteman Cancer Center. After a comprehensive evaluation by ASTRO, Siteman completed the Accreditation Program for Excellence. Read More

Seven Researchers Named AAAS Fellows for 2021

University of Michigan Rogel Cancer Center The University of Michigan Rogel Cancer Center is home to seven members selected as 2021 fellows of the American Association for the Advancement of Science. These researchers are among 564 scientists, engineers and innovators spanning 24 scientific disciplines, recognized for their scientifically and socially distinguished achievements. Read More

Hughes Named a Damon Runyon Fellow

Duke Cancer Institute, Duke University Medical Center Elizabeth R. Hughes, PhD, a postdoctoral associate in the Duke University School of Medicine’s Department of Molecular Genetics and Microbiology, has been named a 2022 Robert Black Fellow by the Damon Runyon Cancer Research Foundation. Read More

Faculty Elected to American Society for Clinical Investigation

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine The American Society for Clinical Investigation has elected two Baylor College of Medicine faculty members to its new class of members. Katherine King, MD, PhD, associate professor of pediatrics – infectious diseases, and Monica Gramatges, MD, PhD, associate professor of pediatrics – oncology, are among 95 new members. Read More
Bertozzi Awarded Wolf Prize in Chemistry

Bertozzi Awarded Wolf Prize in Chemistry

Stanford Cancer Institute Carolyn Bertozzi, PhD, has been jointly awarded the 2022 Wolf Prize in Chemistry for creating a new biochemical field of study and contributing to the understanding of the glycocalyx, a network of cellular molecules important to health and disease. Read More
First Freestanding Cancer Center in Chicago Proposed

First Freestanding Cancer Center in Chicago Proposed

The University of Chicago Medicine Comprehensive Cancer Center The University of Chicago Medicine plans to build a $633 million, 500,000-square-foot facility dedicated to cancer care on its medical campus on the city’s South Side. Kunle Odunsi, MD, PhD, is center director. Photo: Tom Rossiter. Read More
Researchers Elected to American Society for Clinical Investigation

Researchers Elected to American Society for Clinical Investigation

Siteman Cancer Center Two Washington University physician-scientists at Siteman Cancer Center have been elected members of the American Society for Clinical Investigation. Kory Lavine, MD, PhD, and Julie K. Schwarz, MD, PhD, will be inducted April 8. Read More
Jefferson Health Names New Cancer Center Director

Jefferson Health Names New Cancer Center Director

Jefferson Health has named Andrew Chapman, DO, FACP, director of the Sidney Kimmel Cancer Center and executive vice president of oncology services. Dr. Chapman has been serving as the center’s interim director since last year. He began his new position March 15. Jefferson Health President Bruce Meyer, MD, noted that Dr. Chapman's "breadth of experience and expertise, dedication to patient care and success in cancer research made him the ideal fit for this critical role." Read More
Registration Now Open for AACIAACR Hill Day

Registration Now Open for AACI/AACR Hill Day

Registration is now open for the 2022 AACI/AACR Hill Day, scheduled for Wednesday, June 15. Participation in the virtual Hill Day is critical to sharing our message with legislators: that stable, predictable funding increases are essential to advancing research and care at our nation’s cancer centers, and a bipartisan commitment to cancer research is saving and improving millions of lives. Read More

Crowdfunding Helps Pay the Bills During Cancer, But at a Price

University of Michigan Rogel Cancer Center Crowdfunding has become a means for people with cancer to get help managing the financial impact of their disease. But while there’s relief in paying bills, a new study finds that it comes at a cost: a sense of shame and stigma from asking for help and revealing personal health details. The issue is particularly critical for young adults with cancer, an understudied group that faces distinct needs. Read More
Wistar to Be Renamed With 10 Million Gift From Caplan Family

Wistar to Be Renamed With $10 Million Gift From Caplan Family

Ellen and Ronald Caplan Cancer Center of The Wistar Institute The Wistar Institute announces that Ronald Caplan, founder and president of PMC Property Group, Inc., and his wife Ellen, have donated $10 million to Wistar’s National Cancer Institute (NCI)-Designated Cancer Center, which will be renamed the Ellen and Ronald Caplan Cancer Center of The Wistar Institute. Read More
CRI Meeting Registration Open Program Ads Available

CRI Meeting Registration Open, Program Ads Available

Registration is open for the 14th Annual AACI Clinical Research Innovation (CRI) Meeting, which will be held July 12-14 at the Loews Chicago O'Hare Hotel in Rosemont, IL. This year’s meeting theme, "Partnering in Progress," aligns with CRI's strategic goal of stimulating cancer center interactions to maximize resources by creating opportunities for peer-to-peer networking and collaboration. Cancer centers are also invited to support the meeting by purchasing an ad in the program. Read More

Surprise Discovery Suggests New Treatment for Small-Cell Lung Cancer

University of Virginia Cancer Center An unexpected discovery at UVA Cancer Center has allowed scientists to halt the development of small-cell lung cancer in lab mice, and the finding could open the door to a new treatment approach. The researchers were seeking to understand the role of a mutation in the EP300 gene in the formation of small-cell lung cancer tumors. Read More
New Insights Into How Tumors Metabolically Adapt to Their Environment

New Insights Into How Tumors Metabolically Adapt to Their Environment

The University of Chicago Medicine Comprehensive Cancer Center A research team led by Kunle Odunsi, MD, PhD, director of the UChicago Medicine Comprehensive Cancer Center, has discovered novel metabolic mechanisms that contribute to how ovarian cancer escapes from immune attack, and how combination therapies can exploit these pathways to improve ovarian cancer treatment. Read More
New Deputy Director to Lead Research Initiatives Organizational Strategy

New Deputy Director to Lead Research Initiatives, Organizational Strategy

WVU Cancer Institute The WVU Cancer Institute has named Courtney DeVries, PhD, as the new deputy director effective Monday, March 14. She will help lead research initiatives within the Institute. Dr. DeVries joined WVU from Ohio State University, where she was a professor of neuroscience. Read More

Multi-Million Dollar Gift Invests in Expansion of Patient Care

UK Markey Cancer Center UK HealthCare announced a historic $10 million gift from Central Bank to support expanded patient care at the UK Markey Cancer Center. It is the largest gift in UK HealthCare history and launches an initiative to raise $90 million to improve cancer care in Kentucky. Read More
Hirsch Receives Hansen Award

Hirsch Receives Hansen Award

The Tisch Cancer Institute at Mount Sinai Fred Hirsch, MD, PhD, received the 2022 Heine H. Hansen Award from the European Society for Medical Oncology in recognition of his lifelong outstanding contribution to lung cancer research. Dr. Hirsch delivered his award lecture on March 30 at the 2022 European Lung Cancer Conference. Read More
Mesa Delivers Testimony on Clinical Trial Diversity

Mesa Delivers Testimony on Clinical Trial Diversity

On March 17, Ruben A. Mesa, MD, participated in a House Energy and Commerce committee hearing, titled "The Future of Medicine: Legislation to Encourage Innovation and Improve Oversight." The hearing was focused on 22 pieces of legislation to boost biomedical research and innovation, diversify clinical trials, and improve program integrity at the U.S. Food and Drug Administration. Dr. Mesa is a member of AACI's Board of Directors and executive director of Mays Cancer Center at UT Health San Anto…

An Advanced Monitoring Platform Enhances Safety, Precision in Spine Tumor Treatment

Laura and Isaac Perlmutter Cancer Center at NYU Langone The Brain and Spine Tumor Center at NYU Langone’s Perlmutter Cancer Center is now using ExacTrac Dynamic, a patient positioning and monitoring system that helps the spine tumor team address the challenge of patient movement during stereotactic body radiation therapy. Read More

At-Home Screening Program Aims to Reduce Colorectal Cancer Rates in Black Community

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Colorectal cancer experts have launched a new initiative aimed at improving early detection and prevention of colorectal cancer in the Black community, which has historically been placed at increased risk for colorectal cancer due to a lack of timely colorectal cancer screening and barriers to receiving health care services. Read More
Komanduri Named Chief of Hematology Oncology

Komanduri Named Chief of Hematology-Oncology

UCSF Helen Diller Family Comprehensive Cancer Center Krishna Komanduri, MD, has been named the new chief of the Division of Hematology-Oncology at UCSF Health. Dr. Komanduri will also assume two newly created roles on July 1: physician-in-chief of the Helen Diller Family Comprehensive Cancer Center and clinical director of the UCSF Living Therapeutics Initiative. Read More

Research Reveals a New Class of Oncogenic Fusions in Lung and Pancreatic Cancer

Yale Cancer Center, Yale School of Medicine A Yale Cancer Center research team has identified novel oncogenic gene fusions in lung and pancreatic cancer, as well as sarcoma. The fusions involve RASGRF1 (an activator of RAS signaling) and promote cellular changes leading to tumor development. Read More

Mutation Matchmaking

University of New Mexico Comprehensive Cancer Center The UNM Comprehensive Cancer Center has opened the Targeted Agent and Profiling Utilization Registry Study, which is sponsored by the American Society of Clinical Oncology. It matches drugs that target specific cancer mutations to people whose cancers have those mutations, regardless of where their cancers appear or what type of cancer they have. Read More

Molecule That Kills Pancreatic Cancer Cells Discovered

Roswell Park Comprehensive Cancer Center A research team led by scientists at Roswell Park Comprehensive Cancer Center has discovered a molecule that inhibits the growth and metastasis of pancreatic cancer cells through the iron metabolism pathway. Their findings pave the way toward the development of a new drug candidate for the treatment of pancreatic cancer. Read More

Higher Frequency of Blood Mutations in WTC First Responders

Montefiore Einstein Comprehensive Cancer Center The collapse of the World Trade Center (WTC) following the 9/11 attacks exposed first responders to potential carcinogens. A new study reported results from analyzing genes in blood samples from WTC-exposed first responders and non-WTC exposed firefighters. The research team included scientists from Albert Einstein, Vanderbilt-Ingram Cancer Center, Rutgers Cancer Institute of New Jersey, Weill Cornell Medicine, Memorial Sloan Kettering Canc…

Career Development: Making the Transition From Training to Clinician Investigator

The webinar will provide a practical discussion of paths to developing a career in clinical investigation in cancer research. The panel includes physicians who have achieved success in launching clinical research early in their careers who will provide examples of challenges and solutions as well as early career and transition advice.

The Tie Between Taste Bud Receptors and Colorectal Cancer

The University of Kansas Cancer Center About half of people undergoing chemotherapy report changes to their taste buds, such as a bitter taste in their mouth. Discussions with members of the The University of Kansas Cancer Center’s patient research advocacy program, Patient and Investigator Voices Organizing Together, shed light on the issue. Read More
Ragin Named Associate Director of Diversity Equity and Inclusion

Ragin Named Associate Director of Diversity, Equity, and Inclusion

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center has appointed Camille Ragin, PhD, MPH, as associate director of Diversity, Equity, and Inclusion (DEI). In this newly created role, Dr. Ragin will be responsible for enhancing hiring practices to encourage diversity, facilitating more diverse leadership at all levels of the institution, providing training and education on race-related issues to the community, and facilitating collaboration. Read More
Graves Joins Sylvester as Assistant Vice President and Associate Director for Administration

Graves Joins Sylvester as Assistant Vice President and Associate Director for Administration

Sylvester Comprehensive Cancer Center, University of Miami Dorothy Graves, PhD, has been appointed assistant vice president and associate director for administration at Sylvester Comprehensive Cancer Center . She spent five years in her previous leadership role as associate director for administration at UAMS Winthrop P. Rockefeller Cancer Institute. Read More
Blank is New President of the Society of Gynecologic Oncology

Blank is New President of the Society of Gynecologic Oncology

The Tisch Cancer Institute at Mount Sinai Stephanie Blank, MD, associate director of women’s cancer for The Tisch Cancer Institute at Mount Sinai, has taken on the role of president of the Society of Gynecologic Oncology. She most recently served as a president-elect of the professional organization, which advances the prevention, early diagnosis, and treatment of gynecologic cancers. Read More
American Cancer Society Funds Cancer Health Equity Research Center

American Cancer Society Funds Cancer Health Equity Research Center

University of Illinois Cancer Center The American Cancer Society awarded the University of Illinois Cancer Center a $4.08 million, four-year grant to establish the Illinois Cancer Health Equity Research Center, a solutions-oriented consortium of health care researchers and clinicians charged with improving outcomes in communities disproportionately affected by cancer. Jan Kitajewski, PhD, directs the cancer center. Read More

Novel Treatment Makes Pancreatic Cancer Susceptible to Immunotherapy

Siteman Cancer Center A new study in mice suggests that blocking a major inflammatory pathway that is activated in pancreatic cancer makes the tumors sensitive to chemotherapy and a type of immunotherapy that prompts the immune system’s T cells to attack the cancer cells, according to from Washington University researchers at Siteman Cancer Center. Read More

FDA Approves New Immunotherapy Regimen for Melanoma Based on Hopkins Research

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University The U.S. Food and Drug Administration (FDA) has approved a novel therapy for patients with metastatic or inoperable melanoma. The treatment, developed based on original research conducted at the Johns Hopkins Kimmel Cancer Center, is comprised of two immunotherapy agents, relatlimab and nivolumab, which delayed time to cancer progression significantly more than nivolumab alone in a global, multi-center clinical trial. …
Jeffery Named AAAS Fellow

Jeffery Named AAAS Fellow

University of Illinois Cancer Center University of Illinois Cancer Center member Constance Jeffery, PhD, has been named a fellow by the American Association for the Advancement of Science (AAAS). She was honored for pioneering contributions to the understanding of multifunctional proteins and outstanding contributions to the training and mentoring of junior scientists. Read More

Study Tests Drug That Targets Tumor Microenvironment

The University of Kansas Cancer Center Anup Kasi, MD, MPH, is evaluating whether adding a novel agent called CEND-1 helps chemotherapy better permeate cancerous tumors. The Phase I/II investigator-initiated clinical trial, called CENDIFOX, combines CEND-1 and Forfirinox, a standard chemotherapy to treat pancreatic, appendiceal and colorectal cancers. Read More

$3.5 Million Grant to Harness Big Data to Help Hodgkin Lymphoma Patients

Rutgers Cancer Institute of New Jersey With the aid of a recently awarded $3.5 million, five-year National Cancer Institute grant, Rutgers Cancer Institute of New Jersey and Tufts Medical Center in Boston are collaborating to unify global multi-source big data to enhance clinical decision support for improved outcomes for Hodgkin lymphoma patients. Read More

Study Estimates One in Seven U.S. Breast Cancers May Be Over-Diagnosed

Duke Cancer Institute, Duke University Medical Center About one in seven breast cancers detected by mammography screening are over-diagnosed, according to a Duke Cancer Institute study designed to clarify the risk of breast cancer over-diagnosis using contemporary screening technology in the U.S. The study should inform decision-making about mammography screening for women aged 50 and older. Read More

Researchers Identify Gene That Predicts Breast Cancer Patient Treatment Outcomes

Roswell Park Comprehensive Cancer Center A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, two commonly used breast cancer chemotherapies. Read More

New Pathogenic Mechanism in Hematological Malignancies Discovered

Yale Cancer Center, Yale School of Medicine Scientists at Yale Cancer Center have discovered new consequences of specific gene mutations that play a role in the development of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). The new research revealed that mutations in the splicing factor U2AF1 improve the ability of the cancer cells to respond to and survive stress. Read More

For Glioblastoma, a New Clinical Trial Fosters Innovation and Hope

University of Michigan Rogel Cancer Center A new clinical trial from a team at the Rogel Cancer Center uses innovative basic science research methods to offer hope and a new treatment to glioblastoma patients. A team of Rogel physicians led by Daniel Wahl, MD, PhD, hopes that grounding their trial in rigorous and innovative biology from the very beginning will help this approach succeed where so many other potential glioblastoma treatments have failed. Read More

Computational Approach Enables Spatial Mapping of Single-Cell Data Within Tissues

The University of Texas MD Anderson Cancer Center A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types. Read More
Elevated Expertise

Elevated Expertise

University of New Mexico Comprehensive Cancer Center Surgical oncologist Itzhak Nir, MD, is the founding chief of the new Division of Hepato-Pancreatico-Biliary (HPB) Surgery in the UNM Department of Surgery. The division is housed at UNM Comprehensive Cancer Center and provides state-of-the-art care for liver, pancreas and bile duct-gall bladder diseases. Read More

Stand Up to Cancer and Southeastern Cancer Centers Fight Racial Inequities in Lung Cancer

VCU Massey Comprehensive Cancer Center VCU Massey Cancer Center, MUSC Hollings Cancer Center, and UNC Lineberger Comprehensive Cancer Center secured a four-year, $3 million grant from Stand Up To Cancer® (SU2C) that will establish the SU2C Lung Cancer Health Equity Research Team and build on the long-standing community outreach and engagement efforts of these institutions to reduce lung cancer disparities. Read More

Treating Tough Tumors by Exploiting Their Iron Addiction

UCSF Helen Diller Family Comprehensive Cancer Center Researchers at UC San Francisco have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths. Taking advantage of what they discovered to be the cancer cells’ appetite for a reactive form of iron, the researchers tweaked an anticancer drug to operate only in these iron-rich cells, leaving other cells t…
Major Leadership Changes Announced

Major Leadership Changes Announced

Montefiore Einstein Comprehensive Cancer Center Albert Einstein Cancer Center has announced the appointment of three faculty members to key leadership positions, including new deputy director Ulrich Steidl, MD, PhD, reflecting the center’s commitment to basic science, translational, and clinical research and its core principles of diversity, equity, and inclusion. Read More
Bandera Named Unilever Chair for the Study of Diet and Nutrition in the Prevention of Chronic Disease

Bandera Named Unilever Chair for the Study of Diet and Nutrition in the Prevention of Chronic Disease

Rutgers Cancer Institute of New Jersey The Rutgers University Board of Governors voted to approve Elisa Bandera, MD, PhD, an internationally recognized expert in nutrition and cancer epidemiology, as the Unilever Chair for the Study of Diet and Nutrition in the Prevention of Chronic Disease at the Rutgers Cancer Institute of New Jersey. Read More

Study Finds Cancer Treatment Creates Employment Difficulties for Some Rural Women

UAMS Winthrop P. Rockefeller Cancer Institute Rural women are likely to face significant challenges finding secure and reliable employment following cancer treatment if they did not already have a secure job at the time of their diagnosis, according to a new study led by University of Arkansas for Medical Sciences (UAMS) researchers. Read More

Skin Cancer Cells Use an Alzheimer's Disease Protein to Sabotage Immune Defenses

Laura and Isaac Perlmutter Cancer Center at NYU Langone Amyloid beta, a protein known to build up in the brains of people with Alzheimer’s disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds. The study found that in melanoma, cancer cells that have spread to the brain depend on amyloid beta to survive there. Read More

Scientists Target Protein to Lower Risk of Prostate Cancer Spread

Cedars-Sinai Cancer Targeting a specific protein that is often overexpressed in prostate cancer can help prevent or delay the disease from spreading to other parts of the body, according to a study led by Cedars-Sinai Cancer investigators. The research opens the possibility of using available commercial drugs, including one approved by the U.S. Food and Drug Administration for leukemia, to shut down a protein known as receptor-interacting protein kinase 2. Read More

Analysis: Impact of Chronic Lower Extremity Lymphedema on Older Female Cancer Survivors

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute A new study has found that nearly one third of older adult female survivors of colorectal, endometrial, and ovarian cancer have quality of life-impacting challenges with physical activity due to lymphedema in the lower extremities. This is the first study to assess lower lymphedema in colon cancer survivors. Read More
Pietenpol Shyr Named AACR Fellows

Pietenpol, Shyr Named AACR Fellows

Vanderbilt-Ingram Cancer Center The American Association for Cancer Research (AACR) has inducted Jennifer Pietenpol, PhD, and Yu Shyr, PhD, into the 2022 class of Fellows of the AACR Academy. Read More
Li Receives Endowed Chair for Breast Cancer Research

Li Receives Endowed Chair for Breast Cancer Research

Fred Hutchinson Cancer Center Fred Hutchinson Cancer Research Center epidemiologist Christopher Li, MD, PhD, was recently selected as the inaugural recipient of the Helen G. Edson Endowed Chair for Breast Cancer Research. Since joining the Hutch faculty in 2002, Dr. Li has studied connections between breast cancer and lifestyle factors as well as ways to overcome health care disparities. Read More
Irish PM Honors Mc Donnell With National Science Medal

Irish PM Honors McDonnell With National Science Medal

Duke Cancer Institute, Duke University Medical Center Donald McDonnell, PhD, associate director for translational research, Duke Cancer Institute, was awarded the Science Foundation Ireland St. Patrick’s Day Science Medal for his work in the development of new treatments for breast and prostate cancers. Taoiseach (Irish Prime Minister) Micheál Martin TD presented the award in person to McDonnell at a ceremony in Washington, DC. Read More

Cellular Therapy Program Receives Accreditation

WVU Cancer Institute The WVU Cancer Institute Cellular Therapy Program was recently awarded its sixth consecutive Foundation for the Accreditation of Cellular Therapy (FACT) reaccreditation for blood and marrow transplant and first FACT accreditation for immune effector cell therapy (CAR T). Read More

Study: Art at the Bedside of Cancer Patients is Good Medicine

Wilmot Cancer Institute, UR Medicine The simple distraction of looking at art and discussing it helped bring calm to a group of patients at the Wilmot Cancer Institute. The results of a randomized clinical trial show that anxiety was significantly lower among patients who viewed art at the bedside. Read More

Promising Approach Against Treatment-Resistant Cancer

Montefiore Einstein Comprehensive Cancer Center A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them. Read More