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Social Media Policies Can Curb HPV Vaccine Misinformation Improve Public Health Communications

Social Media Policies Can Curb HPV Vaccine Misinformation, Improve Public Health Communications

VCU Massey Comprehensive Cancer Center A new study led by VCU Massey Cancer Center researcher Jeanine Guidry, PhD, compared how HPV vaccination was portrayed on Pinterest before and after the social media platform began moderating vaccine-related content. Findings may help public health officials utilize social media to tackle potentially harmful rhetoric and disseminate trustworthy health information. Read More

Sexual Health Often Overlooked in Cancer Survivorship Care, Especially for Women

Sidney Kimmel Cancer Center at Jefferson Health A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation, and other cancer treatments. In a survey of nearly 400 cancer survivors, 87 percent said they experienced sexual side effects, but most also said their oncologist had not formally asked about them. Female patients were especially unlikely to be asked about sexual dysfunction. Read More
New Strategy for Overcoming Resistance to Immunotherapy Unleashes Power of Dendritic Cells

New Strategy for Overcoming Resistance to Immunotherapy Unleashes Power of Dendritic Cells

Roswell Park Comprehensive Cancer Center Many of the most aggressive and hard-to-treat cancers are highly effective at blocking T cells from reaching and responding to tumors. But research led by Fumito Ito, MD, PhD, FACS, and Roswell Park Comprehensive Cancer Center colleagues details a new strategy for overcoming this resistance by zeroing in on dendritic cells and enhancing their function as "accessory cells" supporting other immune cells. Read More

Genomic Differences May Be Key to Overcoming Prostate Cancer Disparities Among African-American Men

Moffitt Cancer Center Moffitt Cancer Center researchers are taking a closer look at the genomic features of prostate cancer tumors among men of different races in hopes of better understanding why African Americans are more susceptible to the disease. In a new study, the research team describes the immune-oncologic differences in prostate cancer tumors of African-American men and how those variations may be exploited to develop more personalized treatment approaches for this population. …

Changing Gut Microbiota, Taming Inflammation May Help Battle Colorectal Cancer

University of Florida Health Cancer Center Colon cancer may be treated or even prevented by altering microorganisms in the intestine and by combating inflammation with a clinical treatment previously used to treat inflammatory bowel diseases, findings from a study led by the University of Florida suggest. Read More

Activating Inflammasome May Improve Cancer Response to Immunotherapy and PARP Inhibitors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University The inflammasome—a protein signaling network that is activated to rid the body of virus or bacteria-infected cells—may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers. A collaborative research study led by experts at the Johns Hopkins Kimmel Cancer Center and University of Maryland Marlene and Stewart Greenebaum Cancer Center, suppo…

Felsher Receives NCI Outstanding Investigator Award

Stanford Cancer Institute Dean W. Felsher, MD, PhD, is a 2020 recipient of the National Cancer Institute's (NCI) Outstanding Investigator Award. His lab will target the MYC oncogene pathway to treat human cancer using recent fundamental insights into how MYC initiates and maintains tumorigenesis. Read More

Fox Chase Receives Press Ganey 2020 Guardian of Excellence Award

Fox Chase Cancer Center, Temple Health Press Ganey has recognized Fox Chase Cancer Center with its 2020 Guardian of Excellence Award for providing outstanding clinical performance for patients in its outpatient clinics. The award honors organizations who continually perform in the top five percent for patient experience, engagement, or clinical quality performance throughout each quarter of the award year. Read More

Study Documents Racial Differences in U.S. Hospice Use and End-of-Life Care Preferences

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University In a new medical records analysis of racial disparities in end-of-life care, researchers at Johns Hopkins Medicine and three collaborating institutions report that Black patients voluntarily seek substantially more intensive treatment, such as mechanical ventilation, gastronomy tube insertion, hemodialysis, CPR, and multiple emergency room visits in the last six months of life, while white patients more often choose ho…

AI Tool Created to Guide Colorectal Cancer Care With More Precision

Stanford Cancer Institute A new modeling tool may be able to help doctors assess which treatments are best for individual patients with colorectal cancer. The artificial intelligence program analyzes a patient's disease details—such as the stage of cancer and other chronic conditions—and compares those details to other colorectal cancer cases to predict the patient's chance of surviving past 10 years. Read More
Winkfield to Direct Meharry Vanderbilt Alliance

Winkfield to Direct Meharry-Vanderbilt Alliance

Vanderbilt-Ingram Cancer Center Karen Winkfield, MD, PhD, associate director for Community Outreach and Engagement and director of the Office of Cancer Health Equity at Wake Forest Baptist Comprehensive Cancer Center, has been named the new executive director of the Meharry-Vanderbilt Alliance. Read More
AACI Expands Public Policy Resource Library to Track Federal Legislation

AACI Expands Public Policy Resource Library to Track Federal Legislation

AACI recently launched a federal legislation tracking tool for its Public Policy Resource Library (PPRL). The legislation tracker will provide updates on the status of cancer-related bills and will track efforts by AACI and likeminded organizations to advance the legislation. The tracker will specifically highlight federal legislation that has been endorsed by AACI’s Board of Directors. Read More
Clara D Bloomfield Center for Leukemia Outcomes Research Created

Clara D. Bloomfield Center for Leukemia Outcomes Research Created

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute has established a new center dedicated to maintaining and expanding the legacy of the late Clara D. Bloomfield, MD. The center will be initially supported by a $5 million commitment from the OSUCCC – James. Read More

$20 Million Awarded to Expand Access to Care and Community Health Partnerships

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University To improve maternal and children’s health care in the District of Columbia and surrounding communities, the A. James & Alice B. Clark Foundation has invested $20 million to support health care programs at Sibley Memorial Hospital. Sibley and the Johns Hopkins Kimmel Cancer Center will partner to enhance the care of pediatric patients receiving radiation therapy. Read More
Two Research Programs Merged Into New Cancer Biology Program

Two Research Programs Merged Into New Cancer Biology Program

VCU Massey Comprehensive Cancer Center VCU Massey Cancer Center has merged two of its existing research programs into the newly established Cancer Biology program. The former Cancer Cell Signaling and Cancer Molecular Genetics research programs have been consolidated into one new program, which will be led by Azeddine Atfi, PhD. Read More

Collaboration to Accelerate Advancement of Novel Engineered Tumor Infiltrating Lymphocyte Therapy for Solid Tumors

The University of Texas MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center and Obsidian Therapeutics, Inc., have announced a multi-year strategic collaboration designed to expedite the research and development of novel engineered tumor infiltrating lymphocytes for the treatment of solid tumors. Read More
Partnership With American Cancer Society to Address Breast Cancer Disparities

Partnership With American Cancer Society to Address Breast Cancer Disparities

UPMC Hillman Cancer Center The University of Pittsburgh Medical Center (UPMC) is one of just 21 hospital systems in the country and the only system in Pennsylvania selected to work with the American Cancer Society on a community program to promote health equity and equal access to cancer screenings and education with a specific focus on breast cancer. The UPMC team is led by Steven Evans, MD. Read More
Bergan Named Deputy Director

Bergan Named Deputy Director

Fred & Pamela Buffett Cancer Center Raymond Bergan, MD, has accepted the position of deputy director of the Fred and Pamela Buffett Cancer Center. He began his duties on November 9. Dr. Bergan joins the Buffett Cancer Center from the Oregon Health and Sciences University and the Knight Cancer Institute, where he served as associate director for medical oncology among other leadership roles. Read More

Process Accelerated for Delivering New Therapeutics

Huntsman Cancer Institute at the University of Utah A new initiative aims to speed the process of bringing lifesaving medical discoveries made in University of Utah laboratories to new drugs and therapies for patients. The university’s Huntsman Cancer Institute, College of Pharmacy, and the Partners for Innovation, Ventures, Outreach & Technology Center have partnered to establish the University of Utah Therapeutics Accelerator Hub. Read More

New Study to Identify Predictors of Chemotherapy-Associated Pain Condition

Cleveland Clinic Cancer Center Cleveland Clinic data scientist Daniel Rotroff, PhD, and anesthesiologist Joseph Foss, MD, have received a nearly $5 million grant from the National Institute of Neurological Disorders and Stroke to identify biomarkers that can help physicians determine which cancer patients are most likely to develop a chemotherapy-associated pain condition. Read More
Siegel Receives American College of Radiology Honor

Siegel Receives American College of Radiology Honor

Siteman Cancer Center Barry A. Siegel, MD, a professor of radiology and of medicine at Washington University School of Medicine in St. Louis who sees patients at Siteman Cancer Center, has received the College of Radiology’s highest honor for his more than 40 years of leadership in the nuclear medicine community. Read More

Researchers Discover How to Boost Efficacy of Vaccine Designed to Prevent Melanoma Recurrence

The Tisch Cancer Institute at Mount Sinai Nina Bhardwaj, MD, PhD, and Philip Friedlander, MD, PhD, at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, working with colleagues at the Cancer Immunotherapy Trials Network based at the Fred Hutchinson Cancer Research Center, found that adding the small molecule Flt3L, which increases the number of dendritic cells, boosted a cancer vaccine’s effectiveness at producing antibodies and T cells that can later fight melano…

Proteogenomics Enhances the Identification of Therapeutic Vulnerabilities in Breast Cancer

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard, and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer. Read More
Large Scale Cancer Proteomics Study Profiles Protein Changes in Response to Drug Treatments

Large-Scale Cancer Proteomics Study Profiles Protein Changes in Response to Drug Treatments

The University of Texas MD Anderson Cancer Center Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms, and to identify optimal combination treatment strategies. Han Liang, PhD, is senior author of the study. Read More

Age is a Primary Determinant of Melanoma Treatment Resistance, Two Studies Find

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response, according to new findings by Johns Hopkins Kimmel Cancer Center and Johns Hopkins Bloomberg School of Public Health. Read More
Nursing Leader Joins Duke

Nursing Leader Joins Duke

Duke Cancer Institute, Duke University Medical Center Monica Cfarku, RN, MSN, BMTCN, CCM, NE-BC, has been named assistant vice president and chief of Oncology Nursing Services, Duke Cancer Institute. Most recently she was the director of Nursing, Ambulatory Oncology at the Knight Cancer Institute at Oregon Health and Science University in Portland, Oregon. Read More
Study Shows How HIV and Cancer Drugs Accelerate Cellular Aging

Study Shows How HIV and Cancer Drugs Accelerate Cellular Aging

UPMC Hillman Cancer Center A new study led by researchers at UPMC Hillman Cancer Center and the University of Pittsburgh shows for the first time how certain drugs used to treat HIV and cancer drive the cellular aging process, at least in part, by blocking telomeres from replenishing themselves. Patty Opresko, PhD, is senior author on the study. Read More

Using Genetic Data to Overcome Disparities in Colon Cancer Rates

Fred Hutchinson Cancer Center With the help of a three-year, $3.6 million grant from the National Cancer Institute, a team of Fred Hutch public health researchers will lead a collaboration to try to minimize the disparity in colorectal cancer rates between African Americans and Alaska Natives and other ethnic groups. The project is called the Translational Research Program in Colorectal Cancer Disparities. Read More
Fahy Named Endowed Professor

Fahy Named Endowed Professor

University of New Mexico Comprehensive Cancer Center Bridget Fahy, MD, has been appointed to the position of Victor and Ruby Hansen Surface Endowed Professor of Complex Surgical Oncology. Dr. Fahy is currently a professor and chief of the Division of Surgical Oncology in the Department of Surgery at the UNM School of Medicine. She also is the medical coordinator of the UNM Comprehensive Cancer Center’s surgical services. Read More

National Effort to Hasten Treatments for Pancreatic Cancer Enrolling Patients at UF Health

University of Florida Health Cancer Center A novel clinical trial platform that aims to accelerate treatment discoveries for people battling pancreatic cancer is now enrolling patients at 15 sites nationwide, including the University of Florida Health Cancer Center. An initiative of the national nonprofit organization Pancreatic Cancer Action Network, or PanCAN, Precision PromiseSM began development in 2016. Read More

Study Identifies Patients With Lung Cancer Most Likely to Respond to Immunotherapy

UCLA Jonsson Comprehensive Cancer Center Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that patients with a particular type of human leukocyte antigen, a protein scaffold involved in presenting pieces of proteins described as peptides to the immune system, were particularly likely to benefit from immunotherapy. Read More

Positive Outcomes Reported From New Combination Treatment for Ovarian Cancer

Roswell Park Comprehensive Cancer Center A team from Roswell Park Comprehensive Cancer Center has detailed striking findings on the effectiveness of a previously untried combination of old and new drugs as treatment for recurrent ovarian cancer. The researchers report that one-quarter of patients who received the combination of pembrolizumab, bevacizumab, and a pill form of cyclophosphamide experienced long-term disease control along with excellent quality of life. Read More
Active Surveillance Safe for African Americans With Low Risk Prostate Cancer

Active Surveillance Safe for African Americans With Low-Risk Prostate Cancer

UC San Diego Moores Cancer Center In a recent study, Brent Rose, MD, and colleagues tested the hypothesis that African American men undergoing active surveillance are at a significantly higher risk of disease progression, metastases, and death from prostate cancer compared to non-Hispanic white men. Read More
Cancer Health Equity Position Created Assistant Director Named

Cancer Health Equity Position Created, Assistant Director Named

UK Markey Cancer Center UK Markey Cancer Center has appointed Lovoria Williams, PhD, as assistant director for cancer health equity, a newly created position within the Markey leadership structure. The position will form part of the Markey Community Impact Office team, led by Pamela Hull, PhD, Markey’s associate director for population science and community impact. Read More
Golemis Appointed Senior Editor for e Life

Golemis Appointed Senior Editor for eLife

Fox Chase Cancer Center, Temple Health Erica Golemis, PhD, deputy chief science officer and co-leader of the Molecular Therapeutics research program at Fox Chase Cancer Center, was recently appointed senior editor at eLife, an open-access, peer-reviewed journal. The journal is supported by the Howard Hughes Medical Institute and other leading research organizations. Read More
Rini to Lead Study of COVID 19 in Cancer Patients

Rini to Lead Study of COVID-19 in Cancer Patients

Vanderbilt-Ingram Cancer Center Brian Rini, MD, is leading a study launched by the National Cancer Institute that will closely monitor cancer patients who acquire COVID-19 with the goal of providing highly detailed data to guide future care. Read More
Researcher Receives 2 9 Million for Work Improving Lung Cancer Radiation Therapy Effectiveness

Researcher Receives $2.9 Million for Work Improving Lung Cancer Radiation Therapy Effectiveness

Indiana University Melvin and Bren Simon Comprehensive Cancer Center John Turchi, PhD, an Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher, has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective. He is studying the DNA-dependent protein kinase, which is involved in repairing DNA double-strand breaks. Read More
Breast Cancer Discovery Could Help Stop Diseases Deadly Spread

Breast Cancer Discovery Could Help Stop Disease's Deadly Spread

University of Virginia Cancer Center UVA Cancer Center researcher Sanchita Bhatnagar, PhD, and her team have found that the breast cancer oncogene TRIM37 not only causes the cancer to spread but also makes it resistant to chemotherapy. A new approach she and her colleagues have developed could possibly address both, the researchers hope. Read More

Sullivan Honored for Leadership in Quantitative Imaging Biomarkers

Duke Cancer Institute, Duke University Medical Center Daniel Sullivan, MD, a former member of Duke Cancer Institute, was recently honored by the Prevent Cancer Foundation with the James L. Mulshine MD Leadership Award for his work in founding and chairing the Quantitative Imaging Biomarkers Alliance. At the National Cancer Institute, Dr. Sullivan provided leadership to large population-based studies on digital mammography and CT screening for lung cancer. Read More
Champion for Cures Nominations Now Open

Champion for Cures Nominations Now Open

AACI cancer center directors are invited to submit nominations for the 2021 Champion for Cures Award. AACI established the award in 2018 to recognize an individual or individuals who, through direct financial support of an AACI cancer center, demonstrate exceptional leadership in advancing cancer research and care and in inspiring others to do the same. The Champion for Cures Award was presented virtually at the 2020 AACI/CCAF Annual Meeting to Nike, Inc., co-founder Phil Knight and his wife, P…

The Secret Signals Tumor Cell Clusters Use to Drive Metastasis

Fred Hutchinson Cancer Center A research team at Fred Hutchinson Cancer Research Center has outlined their discovery of a secret space between the tumor cells of microscopic clusters where the signal to grow is co-opted and miscommunicated to other cells. They’re now working on new ways to block that signal—call it growth factor "fake news"—in order to stop metastasis in its tracks. Read More
Genome Sequencing Identifies Cancers Achilles Heel in Exceptional Responders

Genome Sequencing Identifies Cancer's Achilles Heel in 'Exceptional Responders'

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Researchers at Baylor College of Medicine led a six-year study with the National Cancer Institute to analyze the tumor genome and microenvironment of advanced cancer patients who live much longer than others with clinically comparable tumors to determine if survival could be explained by genetic mechanisms. David Wheeler, PhD, is lead author on the study. Read More
Boosting Stem Cell Activity Can Enhance Immunotherapy Benefits

Boosting Stem Cell Activity Can Enhance Immunotherapy Benefits

Georgetown Lombardi Comprehensive Cancer Center Immune-system T cells have been reprogrammed into regenerative stem cell-like memory cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center. Samir N. Khleif, MD, headed the research team. Read More
Are E Cigarettes Safer Than Cigarettes Study Sheds Light on the Issue

Are E-Cigarettes Safer Than Cigarettes? Study Sheds Light on the Issue

The University of Kansas Cancer Center In a collaboration between The University of Kansas Cancer Center, California State University San Marcos, and Brown University, scientists conducted a six-week-long randomized trial comparing electronic cigarette use to traditional cigarette use in African-American and Latinx smokers. Nikki Nollen, PhD, served as site principal investigator. Read More
Fang Promoted to Associate Director for Population Science

Fang Promoted to Associate Director for Population Science

Fox Chase Cancer Center, Temple Health Carolyn Y. Fang, PhD, professor and co-leader of the Cancer Prevention and Control Program at Fox Chase Cancer Center, has been promoted to the role of associate director for Population Science. Read More
Miaskowski Recognized by Friends of the National Institute of Nursing Research

Miaskowski Recognized by Friends of the National Institute of Nursing Research

UCSF Helen Diller Family Comprehensive Cancer Center Christine Miaskowski, RN, PhD, FAAN, was awarded the 2020 Ada Sue Hinshaw Award from the Friends of the National Institute of Nursing Research. For 40 years, Dr. Miaskowski has been investigating the causes of, and solutions for, the debilitating side effects of cancer treatment. Read More
Total Deaths Recorded During the Pandemic Far Exceed Those Attributed to COVID 19

Total Deaths Recorded During the Pandemic Far Exceed Those Attributed to COVID-19

VCU Massey Comprehensive Cancer Center For every two deaths attributed to COVID-19 in the U.S., a third American dies as a result of the pandemic, according to study findings from Steven Woolf, MD, MPH, member of the Cancer Prevention and Control research program at VCU Massey Cancer Center. Read More

Researchers Study How the Immune System Responds to COVID-19

Case Comprehensive Cancer Center New research funded by the National Cancer Institute (NCI) aims to boost understanding of how the immune system responds to COVID-19, from the start of infection to recovery. Two projects totaling over $2.6 million are led by Case Western Reserve University and Cleveland Clinic researchers as part of the NCI’s Serological Sciences Network, which awarded just 13 grants nationally. Read More

Study Shows FDA-Approved Leukemia Drug May Help Treat Metastatic Melanoma

UK Markey Cancer Center A new study by UK Markey Cancer Center and UK Department of Pharmacology and Nutritional Sciences demonstrates the potential benefit of using an anti-leukemic drug nilotinib—most commonly used to treat chronic myelogenous leukemia—to overcome therapy resistance in metastatic melanoma. Read More
Possible Strategy Uncovered for Blocking Prostate Tumor Growth in Bone

Possible Strategy Uncovered for Blocking Prostate Tumor Growth in Bone

Roswell Park Comprehensive Cancer Center Led by Subhamoy Dasgupta, PhD, researchers from Roswell Park Comprehensive Cancer Center have determined that prostate tumors change their metabolism to produce more fats, which helps them survive within the bones. Read More

Climate Change Will Give Rise to More Cancers

UCSF Helen Diller Family Comprehensive Cancer Center Climate change will bring an acute toll worldwide, with rising temperatures, wildfires, and poor air quality, accompanied by higher rates of cancer, especially lung, skin, and gastrointestinal cancers, according to a new report from UC San Francisco. An analysis of nearly five dozen published scientific papers identified future effects from global warming on major cancers, from environmental toxins to ultraviolet radiation, air polluti…
Exploring Autophagy as a Therapeutic Strategy Against Frequent Mutations in Non Small Cell Lung Cancer

Exploring Autophagy as a Therapeutic Strategy Against Frequent Mutations in Non-Small Cell Lung Cancer

Rutgers Cancer Institute of New Jersey Rutgers Cancer Institute of New Jersey researcher ‘Jessie’ Yanxiang Guo, PhD, has received a $1.7 million award from the National Institutes of Health to investigate the role of a cellular survival mechanism known as autophagy in the formation of tumors driven by mutations in tumor suppressors known as LKB1 and oncogene KRAS. Read More
Gutmann Receives Neuro oncology Scientific Award

Gutmann Receives Neuro-oncology Scientific Award

Siteman Cancer Center David H. Gutmann, MD, PhD, vice chair for research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis and a Siteman Cancer Center research member, is a recipient of the 2020 Neuro-oncology Scientific Award from the American Academy of Neurology. Read More
CRI Benchmarking Report Published in ASCO Journal

CRI Benchmarking Report Published in ASCO Journal

AACI Clinical Research Innovation (CRI) is pleased to share the publication of an article in the November issue of ASCO’s JCO Oncology Practice. "Clinical Trial Metrics: The Complexity of Conducting Clinical Trials in North American Cancer Centers" summarizes the results of a comprehensive benchmarking survey sent to AACI member centers from 2018-2019 to assess cancer center clinical trials office workload, funding, staffing, and trial activation timelines. Read More

Potential Target Discovered for Treating Aggressive Cancer Cells

Legorreta Cancer Center at Brown University In the past, polyploidal giant cancer cells (PGCCs) have been largely ignored because studies had found that they do not undergo mitosis. However, recent studies have found that PGCCs undergo amitotic budding—cell division that does not occur through mitosis—and that their cell structure enables them to spread rapidly. A new study by a team of Brown University scientists sheds more light and identifies a potential target for treating these aggr…
Western Region Society of Nuclear Medicine Honors Iagaru

Western Region Society of Nuclear Medicine Honors Iagaru

Stanford Cancer Institute The Western Region Society of Nuclear Medicine has presented Andrei Iagaru, MD, with its Sanjiv Sam Gambhir, MD, PhD, 2020 Distinguished Scientist Award. The award was named for Dr. Gambhir, a leader at Stanford, who dedicated his career to developing methods of early disease detection, utilizing molecular imaging to flag signals of disease in its nascent stages. Read More

AACI Urges President Trump to Share Key COVID-19 Information With Biden Transition Team

In a November 20 letter to President Donald Trump, AACI called on the Trump administration to share vital information about its coronavirus response with President-elect Joe Biden and his transition team. AACI joins the American Hospital Association, the American Medical Association, the American Nurses Association, and other major medical associations to ask the Trump administration to cooperate with the Biden transition team to ensure continuity of care for patients, particularly as it relate…

Exploring the Role of Tumor Suppressor Enhancers in the Development of T-cell Acute Lymphoblastic Leukemia

Rutgers Cancer Institute of New Jersey Enhancers are regulatory elements that play an important role in cancer. Researchers from Rutgers Cancer Institute of New Jersey identified a novel enhancer that interacts with a tumor suppressor gene and explored its involvement in normal T cell development as well as in T-cell acute lymphoblastic leukemia. Read More
Cancer Center Receives Grant to Improve Breast Cancer Treatment for Black Women

Cancer Center Receives Grant to Improve Breast Cancer Treatment for Black Women

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Harikrishna Nakshatri, PhD has received a $1.3 million grant from the Department of Defense – Congressionally Directed Medical Research Program’s breast cancer research program. Dr. Nakshatri is identifying the unique biology that may make Black women more susceptible to aggressive breast cancer. Read More
STAT Honors Pioneering Work on Focused Ultrasound Cancer

STAT Honors Pioneering Work on Focused Ultrasound, Cancer

University of Virginia Cancer Center Health news website STAT has honored Natasha Sheybani, PhD, as one of the next generation of scientific superstars for her work in focused ultrasound, cancer immunology, and nuclear medicine while a graduate student at the University of Virginia. Read More
PCLI Webinar Oncology Workforce Challenges

PCLI Webinar: Oncology Workforce Challenges

The AACI Physician Clinical Leadership Initiative (PCLI) will host "Oncology Workforce Challenges: The Role of the Advanced Practice Provider (APP) in Academic Oncology" at 1:00 pm eastern time on Thursday, December 17. Read More

Scientists Discover Roles for a Cellular Motor in Cancer

Huntsman Cancer Institute at the University of Utah Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20 percent of human cancers. Read More

UPMC Hillman Rated Exceptional by NCI

UPMC Hillman Cancer Center UPMC Hillman Cancer Center received an "exceptional" score, the highest achievable rating, and its largest grant to date when it was recently renewed as a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center for another five-year period. The award includes a five-year, $30 million grant. Robert L. Ferris, MD, PhD, is the center's director. Read More

$25 Million Gift Received for Cancer Immunology and Metabolism Center of Excellence

Rutgers Cancer Institute of New Jersey A $25 million anonymous philanthropic gift to Rutgers Cancer Institute of New Jersey will provide groundbreaking support for the Cancer Immunology and Metabolism Center of Excellence. The gift also supports the recruitment of a co-director to lead the center along with Rutgers Cancer Institute Deputy Director Eileen White, PhD. Following a nationwide search, Christian Hinrichs, MD, was recruited from the National Cancer Institute. Read More
Changes Needed to Address Financial Hardship From Cancer

Changes Needed to Address Financial Hardship From Cancer

University of Colorado Cancer Center Cathy Bradley, PhD, deputy director of the University of Colorado Cancer Center, is the lead author of a paper that suggests that it is time to add routine screening for financial hardships after a cancer diagnosis as a quality measure in clinical practice. Read More

$10 Million Gift Supports New Myeloma Research Center

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute has received a $10 million gift from the Paula and Rodger Riney Foundation to establish the Riney Family Foundation Myeloma Center for Advanced Research Excellence. Read More
Mitchell Elected to Fellowship in Royal College of Physicians of London

Mitchell Elected to Fellowship in Royal College of Physicians of London

Sidney Kimmel Cancer Center at Jefferson Health Edith P. Mitchell, MD, FACP, FCPP, FRCP, associate director for diversity affairs at the Sidney Kimmel Cancer Center at Jefferson Health, has been recognized as a fellow of the Royal College of Physicians of London (RCP). The RCP was founded in 1518 by a royal charter from King Henry VIII. Read More
Interim Executive Director Announced

Interim Executive Director Announced

Winship Cancer Institute of Emory University Adam Marcus, PhD, has been appointed interim executive director of Winship Cancer Institute of Emory University. Dr. Marcus assumes the role from Walter J. Curran, Jr., MD, while Emory University conducts a national search for Winship's next executive director. Read More

Democratizing DNA-Based Health Risk Scores

Fred Hutchinson Cancer Center Researchers at Fred Hutchinson Cancer Research Center have been using the strength of large numbers to analyze the genetic variants of different ethnic groups in order to create accurate, unbiased polygenic risk scores for colorectal cancer. Now, they’re doing the same thing in cardiovascular disease, with a $9.8 million grant from the National Heart, Lung, and Blood Institute. Read More
Ohio State Announces Passing of Albert de la Chapelle

Ohio State Announces Passing of Albert de la Chapelle

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute OSUCCC - James has announced the passing of Albert de la Chapelle, PhD, MD, a distinguished university professor in the Department of Cancer Biology and Genetics at Ohio State who played a key role in developing and leading the university’s human cancer genetics program to prominence. Read More

New Cancer Drugs Lead to Life-Threatening Financial Choices

Fred Hutchinson Cancer Center A raft of studies by health outcomes researchers at Fred Hutchinson Cancer Research Center illustrate the difficult choices cancer patients are forced to make regarding an expanding class of targeted drugs called tyrosine kinase inhibitors. Read More
Wakelee Appointed Deputy Director

Wakelee Appointed Deputy Director

Stanford Cancer Institute Heather Wakelee, MD, has been appointed deputy director of the Stanford Cancer Institute, effective January 2021. She has also been named as the new division chief of oncology in Stanford University School of Medicine’s Department of Medicine. Read More

Biomarker of Aggressive Childhood Cancer Discovered

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Johns Hopkins researchers have discovered a new diagnostic marker that distinguishes a fast-growing type of the pediatric brain cancer medulloblastoma from a less aggressive type. The study showed that this biomarker differentiates aggressive group 3 medulloblastoma from the more treatment-responsive group 4 medulloblastoma. Read More
Sadelain Receives Fondation ARC Award

Sadelain Receives Fondation ARC Award

Memorial Sloan Kettering Cancer Center Michel Sadelain, MD, PhD, director of the Center for Cell Engineering at Memorial Sloan Kettering Cancer Center, was named a recipient of the 49th Fondation ARC Léopold Griffuel Award for Translational and Clinical Research. Read More

Key Driver of the Spread of Cancer to the Brain Discovered

VCU Massey Comprehensive Cancer Center Few treatment options exist for patients diagnosed with brain metastases because the mechanisms that allow cancer to spread to the brain remain unclear. However, a study recently published by a VCU Massey Cancer Center scientist offers hope for the development of future therapies by showing how a poorly understood gene known as YTHDF3 plays a significant role in the process. Read More

Clinical Trial Shows Microbubbles May Improve Effectiveness of Radiation Therapy for Liver Cancer

Sidney Kimmel Cancer Center at Jefferson Health Current treatments for liver cancer include a targeted radiation therapy delivered with the help of radiation-emitting glass beads. New research shows that this treatment can be augmented by infusing microbubbles—small gas bubbles surrounded by a lipid shell—into the liver, and popping those bubbles by ultrasound, in a first-in-human pilot clinical trial of the combination. Read More
Hematologist Stem Cell Biologist to Direct Hematology and Cellular Therapy

Hematologist/Stem Cell Biologist to Direct Hematology and Cellular Therapy

Cedars-Sinai Cancer John P. Chute, MD, has been selected to direct the Division of Hematology and Cellular Therapy in the Department of Medicine at Cedars-Sinai Cancer. The physician-scientist also serves as director of the Center for Myelodysplastic Diseases Research and associate director of the Board of Governors Regenerative Medicine Institute in the Department of Biomedical Sciences. Read More
Camp Named Chief of Surgical Oncology

Camp Named Chief of Surgical Oncology

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine E. Ramsay Camp, MD, FACS, has joined the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine as professor and chief of surgical oncology in the Michael E. DeBakey Department of Surgery’s Division of Surgical Oncology. Read More

Research Identifies Safe and Effective Method of Delivering Medicines to the Lungs

Rutgers Cancer Institute of New Jersey Investigators at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School recently identified a new method for safe and effective delivery of medicines to the lungs that can be used for multiple clinical applications, potentially including aerosol vaccination. Read More

New Combination Therapy Could Help Fight Difficult-to-Treat Cancers With Common Mutations

UCLA Jonsson Comprehensive Cancer Center UCLA Jonsson Comprehensive Cancer Center scientists have found a new combination therapy that suppresses the MAPK pathway by holding cancer-driving proteins in a death grip. This combination of two small molecules has the potential to treat not only BRAF mutated melanoma but also additional aggressive subtypes of cancers, including melanoma, lung, pancreatic, and colon cancers that harbor RAS or NF1 mutations. Read More

FDA Approval Granted for Prostate Cancer Imaging Technique

UCSF Helen Diller Family Comprehensive Cancer Center Two University of California medical centers, UC San Francisco and UCLA, and their nuclear medicine teams have obtained approval from the U.S. Food and Drug Administration to offer a new imaging technique for prostate cancer that locates cancer lesions in the pelvic area and other parts of the body to which the tumors have migrated. The PSMA PET technique is highly effective in detecting prostate cancer throughout the body so that it c…
Multiple Myeloma Expert Joins Sylvester Leadership

Multiple Myeloma Expert Joins Sylvester Leadership

Sylvester Comprehensive Cancer Center, University of Miami Hematologic oncologist C. Ola Landgren, MD, PhD, is the inaugural leader of a new research program, experimental therapeutics, at Sylvester Comprehensive Cancer Center, University of Miami Health System. Dr. Landgren was chief of myeloma service for the past six years at Memorial Sloan Kettering Cancer Center. Read More

Initiative Seeks to Extract Cancer Phenotypes From Electronic Health Records

Vanderbilt-Ingram Cancer Center The National Cancer Institute has awarded a $4.35 million grant for the development of interactive visual tools that will allow researchers to extract cancer phenotypes from electronic medical records. The five-year grant was awarded based upon the work of the Cancer Deep Phenotype Extraction (DeepPhe) project. Read More
Mc Donnell Elected to National Academy of Inventors

McDonnell Elected to National Academy of Inventors

Duke Cancer Institute, Duke University Medical Center Donald McDonnell, PhD, has been elected as a fellow to the National Academy of Inventors. Using a combination of genetics, biochemistry, and chemical biology, Dr. McDonnell explores fundamental mechanistic aspects of estrogen receptor signaling in breast cancer. Read More
Sequencing Study Highlights Previously Unknown Myeloma Resistance Mechanisms

Sequencing Study Highlights Previously Unknown Myeloma Resistance Mechanisms

Roswell Park Comprehensive Cancer Center A group of researchers led by Maximillian Merz, MD, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma. Read More

Three Roswell Park Experts Acknowledged as Influential Researchers

Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center’s Igor Puzanov, MD, MSCI, FACP, Andrew Hyland, PhD, and Maciej Goniewicz, PhD, PharmD, have all recently been recognized as global scientific pioneers on the 2020 Clarivate Plc Highly Cited Researchers list. Read More
Odunsi Named Director of the University of Chicago Medicine Comprehensive Cancer Center

Odunsi Named Director of the University of Chicago Medicine Comprehensive Cancer Center

Adekunle “Kunle” Odunsi, MD, PhD, FRCOG, FACOG, an expert in immunotherapy and vaccine therapy for cancer, has been appointed director of the University of Chicago Medicine Comprehensive Cancer Center, effective March 1. Dr. Odunsi will also serve as BSD Dean for Oncology and professor of obstetrics and gynecology at the University of Chicago. He joins UChicago from Roswell Park Comprehensive Cancer Center, where he served as deputy director, executive director of the Center for Immunotherapy, …
PCLI Welcomes New Steering Committee Members

PCLI Welcomes New Steering Committee Members

Three new members have been selected to join AACI’s Physician Clinical Leadership Initiative (PCLI) Steering Committee: Carrie B. Lee, MD, MPH, UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; Karen L. Reckamp, MD, MS, Cedars-Sinai Cancer; and Julie Ann Sosa, MD, MA, FACS, MAMSE, FSSO, UCSF Helen Diller Family Comprehensive Cancer Center. The new members’ terms began January 1. Read More
Scientists Discover Promising Key to Preventing Cancer Relapse After Immunotherapy

Scientists Discover Promising Key to Preventing Cancer Relapse After Immunotherapy

The Tisch Cancer Institute at Mount Sinai Joshua Brody, MD, and Mount Sinai colleagues have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at? Read More
Call for Abstracts for the 13th Annual AACI CRI Meeting

Call for Abstracts for the 13th Annual AACI CRI Meeting

The AACI CRI Steering Committee is currently soliciting abstracts for the 13th Annual AACI CRI Meeting. This year’s meeting theme will focus on adapting cancer clinical research for 2021 and beyond. The purpose of the abstracts is to inform meeting attendees about clinical trials office challenges and solutions implemented at AACI cancer centers. The online submission tool will open in February. In the meantime, you may draft your abstract using the AACI CRI abstract template.  Read More
Researchers Discover Men Fighting Both Cancer and COVID 19 at Higher Risk Than Women

Researchers Discover Men Fighting Both Cancer and COVID-19 at Higher Risk Than Women

The University of Kansas Cancer Center Men with cancer and COVID-19 may be at significantly higher risk for severe symptoms and even death as compared to females fighting both, a University of Kansas Cancer Center research team led by Anup Kasi, MD, MPH, has found. Read More
Study Shows Regional Variation in Prostate Cancer Genomic Testing

Study Shows Regional Variation in Prostate Cancer Genomic Testing

Yale Cancer Center, Yale School of Medicine In a new study by Yale Cancer Center, researchers found substantial regional variation in use of genomic testing for prostate cancer, raising questions about access and other factors that might promote rapid adoption of new cancer technologies. Michael Leapman, MD, is lead author of the study. Read More

Pod E-Cigarettes Less Harmful Than Regular Cigarettes, Study Finds

Legorreta Cancer Center at Brown University In the first-ever clinical trial of fourth-generation electronic cigarettes, researchers found that adults who switched to e-cigarettes had lower levels of a major carcinogen compared to smokers who continued using combustible cigarettes. Read More

Grant Bolsters Deep Tissue Imaging Research

Vanderbilt-Ingram Cancer Center Researchers in the Vanderbilt University Institute of Imaging Science have received a $1 million grant from the Chan Zuckerberg Initiative to develop "deep tissue" imaging methods that can peer into the furthest corners of the body. Read More

FY 2021 Budget a Mixed Bag for Cancer Research

Approved by the House and Senate on Monday, December 21, 2020, the final Fiscal Year 2021 budget deal includes a $1.25 billion increase in funding for the National Institutes of Health (NIH) and a $119.5 million increase to the National Cancer Institute (NCI). While the additional funding does not meet levels requested by AACI, the association is grateful for the significant additional support approved by legislators on both sides of the aisle. The bill also addresses three of AACI's public pol…

Study: Potential Cancer Therapy May Boost Immune Response

Cedars-Sinai Cancer A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by Cedars-Sinai Cancer investigators. Read More
More Cancer Patients Could Benefit From Rehabilitation Researcher Says

More Cancer Patients Could Benefit From Rehabilitation, Researcher Says

WVU Cancer Institute In a new systematic review, Nicole Stout, DPT, FAPTA, and her colleagues identified rehabilitation recommendations included in cancer-treatment guidelines from around the world. The guidelines recommended rehabilitation for a variety of cancer types and consequences of cancer treatment. But the researchers discovered a disconnect between what the guidelines suggested and what many doctors do. Read More

Drugs Create Balancing Act for Patients With Non-Small Cell Lung Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University A large retrospective study of patients who received a form of immunotherapy for non-small cell lung cancer revealed that patients may get more than one immune-related side effect, and identified a correlation between these multisystem immune-related adverse events (irAEs) and improved patient survival. In fact, patients who developed two irAEs did better, in terms of delaying the time to cancer progression and overall…