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Cote Named a National Academy of Inventors Senior Member

Cote Named a National Academy of Inventors Senior Member

Siteman Cancer Center Richard J. Cote, MD, a research member at Siteman Cancer Center, has been elected a senior member of the National Academy of Inventors. He has developed tools for analyzing tumor cells and predicting disease progression and response to therapy. Read More

Virtual Human Intervention Allows for Colorectal Cancer Screening From Home

University of Florida Health Cancer Center A new University of Florida Health intervention gives patients who qualify access to colorectal cancer screening information and tests from the comfort of their own homes. Two recent UF studies examine new ways to effectively reach all patients with a new communication tool using a virtual health assistant, or VHA, to deliver a colorectal cancer screening program. Read More
Process Ensures Follow up of Incidental Radiology Findings

Process Ensures Follow-up of Incidental Radiology Findings

Vanderbilt-Ingram Cancer Center When people go to an emergency room after being injured, suspicious images may show up on scans that are unrelated to their injuries but may indicate cancer. A team at Vanderbilt University Medical Center recently established a better process for ensuring these patients receive follow-up diagnostic care, an initiative that is receiving national recognition. Read More
Chiang Appointed Deputy Chief Medical Officer and Chief Integration Officer at Smilow

Chiang Appointed Deputy Chief Medical Officer and Chief Integration Officer at Smilow

Yale Cancer Center, Yale School of Medicine Anne Chiang, MD, PhD, has been named deputy chief medical officer and chief integration officer at Smilow Cancer Hospital. Dr. Chiang will partner with Smilow leadership to further expand multidisciplinary cancer services across the care center network. Read More

New Test Predicts Tumors Most Likely to Respond to Radiation, Chemotherapy

UCSF Helen Diller Family Comprehensive Cancer Center New research led by scientists from UC San Francisco and the Catalan Institute of Oncology in Barcelona shows that a distinctive pattern of gene activity within tumor cells is present in many cases of common cancers and could help predict who is most likely to benefit from "genotoxic" therapies. Mary Helen Barcellos-Hoff, PhD, is co-senior author of the paper. Read More
Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

UC San Diego Moores Cancer Center Gastrointestinal stromal tumors (GIST) cannot be cured by drugs alone, and targeted therapies are only modestly effective, with a high rate of drug resistance. In a recent study, researchers at University of California San Diego School of Medicine and Moores Cancer Center identified new therapeutic targets that could lead to new treatment options for patients. Jason Sicklick, MD, is the study's senior author. Read More
AACI Marks the Passing of UVA Cancer Center Director Emeritus Michael Weber

AACI Marks the Passing of UVA Cancer Center Director Emeritus Michael Weber

Michael J. Weber, PhD, has passed away following a battle with pancreatic cancer. Dr. Weber was key to the founding of the University of Virginia Cancer Center in 1984, obtaining a grant from the National Cancer Institute (NCI) that partially paid to renovate laboratories to house investigators. Based on its strengths in fundamental laboratory science, the cancer center received its NCI designation in 1987. Read More

New State Bill Eliminates Barriers to Treatment for Stage IV Cancer Patients

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Ohio Governor Mike DeWine has signed into law a new bill to ensure immediate access to treatment for Stage IV cancer patients in the state, a move that cancer physicians with OSUCCC – James cite as of critical importance for patients facing advanced cancers. Read More
Team Builds First Model of Progression of AML Using CRISPR

Team Builds First Model of Progression of AML Using CRISPR

The Tisch Cancer Institute at Mount Sinai A research team led by the Icahn School of Medicine at Mount Sinai has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify potential therapeutic targets for early disease stages. Eirini Papapetrou, MD, PhD, is senior author of the study. Read More

Targeted RNA Nanoparticle Shows Early Promise as Treatment for Liver Cancer

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute A new targeted RNA nanoparticle designed to carry a chemotherapy drug along with a therapeutic oligonucleotide against chemical efflux gene might provide an effective treatment for liver cancer, according to a new study led by researchers at OSUCCC – James. Read More

New Method of Counting Tumor Cells Offers Possibility of a Liquid Biopsy

Case Comprehensive Cancer Center In a new study, researchers led by Aaron Fleischman, PhD, and Maciej Zborowski, PhD, report on a new device they’ve developed to identify and perform differential counts of circulating tumor cells, which their findings suggest may be more accurate and help to better assess cancer metastasis risk. Read More

Drug-Delivery Microcapsules Tagged With Zirconium-89 Can Be Tracked by PET Imaging

O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham University of Alabama at Birmingham polymer and radionuclide chemists report what they believe may represent a major step forward in microcapsule drug delivery systems. The UAB microcapsules—labeled with radioactive zirconium-89—are the first example of hollow polymer capsules capable of long-term, multiday positron emission tomography, or PET, imaging in vivo. Read More

Pandemic Brings Career Setbacks for Women in Medicine

UCSF Helen Diller Family Comprehensive Cancer Center Women in academic medicine are facing the prospect of career setbacks as a result of the COVID-19 pandemic. Katherine Van Loon, MD, MPH, and Bridget Keenan, MD, PHD, recently published their views on the issue and offered solutions for institutions. Read More

Validation of Novel Prognostic Index May Better Inform Burkitt Lymphoma Treatment

Rutgers Cancer Institute of New Jersey Rutgers Cancer Institute of New Jersey, together with RWJBarnabas Health, have announced the publication of research that has identified and validated the novel Burkitt Lymphoma International Prognostic Index in patients with this rare, high-grade B-cell lymphoma that is often studied in trials with small sample sizes. Read More

Technology Could Upend DNA Sequencing for Diagnosing Certain DNA Mutations

VCU Massey Comprehensive Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. However, a breakthrough developed by researchers at Massey Cancer Center promises to diagnose DNA rearrangement mutations at a fraction of the cost with improved accuracy. Read More

SRC-3 is a Novel Regulator of Human Immune T Regulatory Cells

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human breast and other cancers. Read More

New Prostate Cancer Test Could Avoid Unnecessary Biopsies

University of Michigan Rogel Cancer Center A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. Read More

Children's Mercy Joins Pediatric Early Phase Clinical Trials Network

The University of Kansas Cancer Center Children’s Mercy has been designated a non-core member of the Pediatric Early Phase Clinical Trials Network, enhancing their ability to deliver the latest leading-edge pediatric cancer clinical trials. Children’s Mercy is recognized by the National Cancer Institute as a consortium partner of The University of Kansas Cancer Center. Read More
Spratt Named New Chair of Radiation Oncology

Spratt Named New Chair of Radiation Oncology

Case Comprehensive Cancer Center Daniel E. Spratt, MD, will join the UH Seidman Cancer Center team and hold the Vincent K. Smith chair in radiation oncology, effective May 1. Dr. Spratt joins Seidman—part of the Case Comprehensive Cancer Center consortium—from the University of Michigan. Read More
2021 Brings Changes to Research Programs Leadership

2021 Brings Changes to Research Programs, Leadership

Duke Cancer Institute, Duke University Medical Center In a recent message to faculty, Duke Cancer Institute Director Michael B. Kastan, MD, PhD, detailed institutional changes, including new program names and newly appointed leaders, including new associate directors in basic research and translational research. Read More
Paper on Protected Time for Clinician Investigators Published

Paper on Protected Time for Clinician Investigators Published

The Journal of the National Comprehensive Cancer Network has published “Status of the Clinician Investigator in America: An Essential Health Care Provider Driving Advances in Cancer Care,” a report based on an AACI survey about protected time for research efforts. The lead author is Randall F. Holcombe, MD, MBA, director of the University of Hawai‘i Cancer Center, and past chair of AACI’s Physician Clinical Leadership Initiative (PCLI) Steering Committee. Read More

COVID-19 Infection in Immunodeficient Patient Cured by Infusing Convalescent Plasma

O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham A 72-year-old woman was hospitalized with severe COVID-19 disease, 33 days after the onset of symptoms. She was unable to mount her own immune defense against the SARS-CoV-2 virus because of chronic lymphocytic leukemia. But when physicians at the University of Alabama at Birmingham recommended a single intravenous infusion of convalescent blood plasma from her son-in-law—who had recovered from COVID-19 disease…

Cancer Patients and COVID-19 Vaccines

Fred Hutchinson Cancer Center The initial batch of COVID-19 vaccines are now available in the U.S. following incredibly fast development and testing. Not so incredibly, there’s a lot of confusion among cancer patients, as well as their oncologists and caregivers, as to whether the vaccine is a good or bad idea for somebody dealing with cancer. Read More

Genetic Tool Improves Estimation of Prostate Cancer Risk in Diverse Ethnic, Racial Groups

UC San Diego Moores Cancer Center Building upon previous research, an international team led by scientists at University of California San Diego School of Medicine has validated a more inclusive and comprehensive genetic tool for predicting age of onset of aggressive prostate cancer. Read More
Pledge Honors Wife Family

Pledge Honors Wife, Family

UAMS Winthrop P. Rockefeller Cancer Institute The University of Arkansas for Medical Sciences has received a $1 million pledge from Larry Crain, Sr., to support the Winthrop P. Rockefeller Cancer Institute’s pursuit of National Cancer Institute designation. In appreciation of the gift, the Seed of Hope Garden on the cancer institute’s ground floor will be renamed for Crain’s late wife, Janett, who died in 2018 after a brief battle with cancer. Read More

Grant to Address Cancer Health Inequities

Yale Cancer Center, Yale School of Medicine Biotechnology company Genentech, a member of the Roche Group, has awarded a two-year, $750,000 research grant to Yale Cancer Center and Smilow Cancer Hospital to measure, address, and create accountability around cancer health inequities. Read More
Family Gives 1 Million for NCI Designation

Family Gives $1 Million for NCI Designation

UAMS Winthrop P. Rockefeller Cancer Institute The Schueck/McCarty family has pledged $1 million to the University of Arkansas for Medical Sciences Winthrop P. Rockefeller Cancer Institute to support its efforts in achieving National Cancer Institute designation. Marge Schueck (center) and her children, Patrick Schueck and Jennifer Schueck McCarty, are pictured at left. Read More

Kansas

In 2007, the State of Kansas established a budget line item of $5 million per year in support of The University of Kansas Cancer Center’s goal of obtaining National Cancer Institute (NCI) designation. This funding played an essential role in the cancer center’s NCI designation in 2012, and supports cancer research, education, and outreach.
Register Today for the 13th Annual AACI CRI Meeting

Register Today for the 13th Annual AACI CRI Meeting

Registration is open for the 13th Annual AACI Clinical Research Innovation (CRI) Meeting, which will be held virtually July 13-15. The three-day online meeting will deliver the innovative, quality education that AACI members have enjoyed at prior CRI annual meetings. This year’s meeting theme will focus on adapting cancer clinical research for 2021 and beyond. Read More

Researchers Developing New Cancer Immunotherapy Drug

University of Florida Health Cancer Center University of Florida Health Cancer Center researchers have found a potential new way of targeting tumor-infiltrating regulatory T cells that could possibly benefit a large population of cancer patients, including those who will not respond to other immunotherapies. Read More

Blood Discoveries Advance Effort to Grow Organs, Battle Cancer

University of Virginia Cancer Center Pioneering research into how our bodies manufacture the cells that make blood has moved us closer to regrowing tissues and organs. The findings also may let doctors grow the cells for transplantation into people to battle cancer, blood disorders, and autoimmune diseases. Read More
Kim and Tim Eberlein Distinguished Professorship Established

Kim and Tim Eberlein Distinguished Professorship Established

Siteman Cancer Center A newly created Washington University professorship honors the contributions of Timothy J. Eberlein, MD, director of Siteman Cancer Center, and his wife, Kimberley A. Eberlein (pictured at left with Dr. Eberlein), who had a distinguished career in health care administration and now holds leadership positions in arts organizations in St. Louis. The inaugural recipient is Ryan C. Fields, MD. Read More
PCLI Webinar The State of Telehealth

PCLI Webinar: The State of Telehealth

AACI's Physician Clinical Leadership Initiative (PCLI) will host "The State of Telehealth" on Wednesday, March 10 at 1:00 pm eastern time. The webinar will examine the impact of the COVID-19 pandemic on telemedicine. Read More
First Lady Jill Biden Visits Massey to Discuss Cancer Disparities Community Engaged Research

First Lady Jill Biden Visits Massey to Discuss Cancer Disparities, Community Engaged Research

VCU Massey Comprehensive Cancer Center Jill Biden, EdD, the First Lady of the United States, met with scientists, doctors, and community leaders at Virginia Commonwealth University Massey Cancer Center to learn how they are working together to address cancer disparities. She toured several Massey labs and learned about the cutting-edge cancer research being conducted. Read More
AACI Launches Cancer Health Disparities Podcast

AACI Launches Cancer Health Disparities Podcast

A new podcast from AACI aims to expand the dialogue about cancer health disparities and to identify strategies to mitigate them. Accelerating Equity: Cancer Care for All is hosted by AACI President Karen E. Knudsen, MBA, PhD. Her first guest was Norman E. Sharpless, MD, director of the National Cancer Institute. Read More
Tackett Named Deputy Director

Tackett Named Deputy Director

UAMS Winthrop P. Rockefeller Cancer Institute Cancer researcher Alan Tackett, PhD, has been named deputy director of the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas for Medical Sciences (UAMS). He previously served as associate director of basic research for the UAMS Cancer Institute. Read More

Researchers Receive $6 Million to Explore New Pancreatic Cancer Therapies

UCLA Jonsson Comprehensive Cancer Center A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer. Read More

AACI Issues Statement Condemning Racism, Violence

Prompted by a recent mass shooting targeting Asian-American women, AACI issued a formal statement urging the cancer community, policymakers, and other stakeholders to address racism, discrimination, and gun violence as public health crises. In the statement, the association highlighted the responsibility of its Board of Directors, staff, and cancer center leaders to improve health outcomes for all people — not just as they relate to cancer, but in all facets of public health. Read More

Virtual Human Intervention Allows for Colorectal Cancer Screening at Home

University of Florida Health Cancer Center A new University of Florida Health intervention gives patients who qualify access to colorectal cancer screening information and tests from the comfort of their own homes. Two recent UF studies examine new ways to effectively reach patients with a new communication tool using a virtual health assistant. Read More
Cracking the Case of a Deadly Type of Kidney Cancer

Cracking the Case of a Deadly Type of Kidney Cancer

Duke Cancer Institute, Duke University Medical Center A research team led by Andrew Armstrong, MD, MSc, has identified new targets in metastatic non-clear cell renal cell carcinoma that could lead to the development of innovative therapies in this disease. Read More
American Psychosocial Oncology Society Recognizes Work with Cancer Survivors

American Psychosocial Oncology Society Recognizes Work with Cancer Survivors

The University of Arizona Cancer Center Outstanding professional dedication to the needs of cancer survivors and their caregivers has earned a lifetime achievement award for Terry Badger, PhD, RN, PMHCNS-BC, FAPOS, FAAN, from the American Psychosocial Oncology Society. Read More

2021 AACI/CCAF Annual Meeting Shifts to Virtual Format

To prioritize the health and well-being of AACI meeting attendees, supporters, and cancer center patients, AACI's Board of Directors and the 2021 AACI/CCAF Annual Meeting Program Committee have decided not to move forward with an in-person meeting in Kansas City. Instead, the annual meeting will take place October 19-21 in a virtual format. The meeting was previously scheduled for October 17-19.  Read More
Register Today for the 2021 AACIAACR Virtual Hill Day

Register Today for the 2021 AACI/AACR Virtual Hill Day

Registration is now open for the 2021 AACI/AACR Hill Day, scheduled for Wednesday, June 9. The virtual advocacy day will consist of video and conference call meetings organized by Soapbox, a firm that specializes in coordinating advocacy days. Hill Day is open to all AACI and AACR members who wish to participate. Read More
Cancer Research Pioneer Jose Baselga Dies at 61

Cancer Research Pioneer Jose Baselga Dies at 61

American Association for Cancer Research José Baselga, MD, PhD, who was a major force in the development of molecularly targeted therapies, died March 21 at age 61 from Creutzfeldt-Jakob disease. He was a past president of the American Association for Cancer Research, former chief medical officer of Memorial Sloan Kettering Cancer Center, and executive vice president for R&D oncology at AstraZeneca. Read More
Study Finds Lower Costs Better Outcomes in Prostate Cancer Therapy

Study Finds Lower Costs, Better Outcomes in Prostate Cancer Therapy

The University of Vermont Cancer Center An interdisciplinary team of Vermont researchers and a partner at Yale's Smilow Cancer Center conducted an economic evaluation to establish an overall cost-effectiveness comparison of two approaches to the treatment of low-volume metastatic prostate cancer. Lead author is Nataniel Lester-Coll, MD. Read More
4 2 Million Awarded for Breast Cancer Chemoprevention Study

$4.2 Million Awarded for Breast Cancer Chemoprevention Study

The University of Kansas Cancer Center The University of Kansas Cancer Center researchers have received a $4.2 million grant from the National Cancer Institute to study bazedoxifene and low-dose conjugated estrogen in women who are at increased risk for developing breast cancer and are experiencing menopausal symptoms. Carol Fabian, MD, is principal investigator. Read More

Program Develops Cancer Education Curriculum for Appalachian Schools

UK Markey Cancer Center After conducting a study to assess the need for cancer education materials in Appalachian Kentucky, members of UK Markey Cancer Center’s Appalachian Career Training in Oncology program worked with faculty from the UK College of Education to create a three-part cancer education curriculum for middle and high school teachers in the region. Read More
Novel Drug Combo Shows Promise Against Triple Negative Breast Cancer

Novel Drug Combo Shows Promise Against Triple-Negative Breast Cancer

City of Hope Comprehensive Cancer Center City of Hope scientists have combined a checkpoint inhibitor with an anti-parasitic drug, ivermectin, to successfully treat triple-negative breast cancer in preclinical research, according to a new study led by Peter P. Lee, MD. (Ivermectin is also currently being used in clinical trials to treat and prevent COVID-19.) Read More
Cancer Care at Network Sites Survey Results Published

Cancer Care at Network Sites Survey Results Published

In a survey of the status of care across cancer center networks, AACI has found that many opportunities exist for such networks to increase patient satisfaction and outcomes and decrease treatment delays and risks. A report based on the survey’s findings has been published by the Journal of the National Comprehensive Cancer Network. AACI Past President Stanton L. Gerson, MD, is the lead author. Read More
Brain Tumor Center Established

Brain Tumor Center Established

Siteman Cancer Center Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital have established the Brain Tumor Center. The multidisciplinary practice of physicians and scientists will provide leading-edge, patient-centric care for brain tumor patients while developing transformative basic, translational, and clinical research on new therapies. Albert H. Kim, MD, PhD, is inaugural director. Read More

Studies Support Updated USPSTF Lung Cancer Screening Guidelines

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Two new studies published by investigators at The Ohio State University and the UNC Lineberger Comprehensive Cancer Center provide important evidence review and predictive modeling data to inform updated lung cancer screening guidelines implemented by the U.S. Preventive Services Task Force (USPSTF). Read More

Response to Cancer Immunotherapy May Be Affected by Genes We Carry From Birth

UCSF Helen Diller Family Comprehensive Cancer Center A new study finds that inherited genetic variation plays a role in who is likely to benefit from checkpoint inhibitors. The study also points to potential new targets that could help even more patients unleash their immune systems' natural power to fight off malignant cells. Read More

Researchers Illuminate Potential Precursors of Blood Cancers

Huntsman Cancer Institute at the University of Utah Utah researchers report significant new insights into the development of blood cancers. In recently published work scientists describe an analysis of published data from more than 7,000 patients diagnosed with leukemia and other blood disorders. Read More
Cancer Tricks Immune Cells Immunotherapy Can Take Advantage

Cancer Tricks Immune Cells, Immunotherapy Can Take Advantage

UPMC Hillman Cancer Center A study conducted by a team of scientists at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine, led by Greg Delgoffe, PhD, shows how chemicals in the tumor microenvironment subvert the immune system and enable cancer to evade attack. Read More

Earlier Colonoscopies Reduce Subsequent Cancer Risk by Half

Stanford Cancer Institute Stanford researchers have found that initiating colonoscopy screening between the ages of 45 and 49 halves the risk of subsequent development of colorectal cancers. Read More

Collagen Plays Protective Role During Pancreatic Cancer Development

The University of Texas MD Anderson Cancer Center Contrary to long-held beliefs, Type I collagen produced by cancer-associated fibroblasts may not promote cancer development but instead plays a protective role in controlling pancreatic cancer progression, reports a new study from researchers at The University of Texas MD Anderson Cancer Center. Raghu Kalluri, MD, PhD, is senior author. Read More

Cancer Immunotherapy Approach Targets Common Genetic Alteration

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University A new cancer immunotherapy prototype uses engineered T cells to target a genetic alteration common among all cancers. The approach, which stimulates an immune response against cells that are missing one gene copy, was developed at the Ludwig Center, Lustgarten Laboratory and the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center. Read More
National Organization for Rare Disorders Honors Sicklick

National Organization for Rare Disorders Honors Sicklick

UC San Diego Moores Cancer Center Jason Sicklick, MD, FACS, a surgical oncologist at Moores Cancer Center at UC San Diego Health, was recently announced as an award honoree by the National Organization for Rare Disorders. Read More
Marine Natural Product Discovered Off Florida Coast Could Help Fight Cancer

Marine Natural Product Discovered Off Florida Coast Could Help Fight Cancer

University of Florida Health Cancer Center From cyanobacteria blooms found off the Florida coast near Fort Lauderdale, University of Florida researchers have discovered a novel marine natural product that binds to a new site of tubulin, an important target for cancer drugs. Read More
A Measure of Cleanliness

A Measure of Cleanliness

University of New Mexico Comprehensive Cancer Center Michelle Ozbun, PhD, and her team developed a way to measure how many infectious human papillomavirus particles are left on a surface after it has been disinfected. They used sophisticated microscopic techniques developed at the UNM Comprehensive Cancer Center to count how many cells are infected and how many virus particles were present. Read More

New Director of Neuro-Oncology Named

Rutgers Cancer Institute of New Jersey Rutgers Cancer Institute of New Jersey has named Michael E. Salacz, MD, as director of its neuro-oncology program. He joins Rutgers from the University of Kansas Medical Center, where he directed the brain and spine tumor program. Read More
Reimagining Palliative Care Learning During a Pandemic

Reimagining Palliative Care Learning During a Pandemic

Stanford Cancer Institute Kavitha Ramchandran, MD, and her team have drawn on their knowledge of both online and in-person environments to develop a virtual palliative medicine clerkship to provide Stanford medical students the training they need during the pandemic. Read More

New Barrett's Esophagus Monitoring Method Could Aid in Easier, More Precise Prognoses

Case Comprehensive Cancer Center A new technique for sampling and testing cells from Barrett's esophagus patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or are at high risk of progressing toward cancer, according to investigators at Case Western Reserve University and Johns Hopkins Kimmel Cancer Center. Read More

Current Liver Cancer Screenings May Leave African Americans at Greater Risk

The Tisch Cancer Institute at Mount Sinai Mount Sinai researchers found that nearly one-third of Black patients in their study would not have qualified for liver cancer screening using common cirrhosis measures. The study also found that at the time of diagnosis, the tumors in Black patients tended to be larger, more numerous, more aggressive, and more invasive. Read More
Cancer Patients Most Worried About Finances Have Worse Outcomes

Cancer Patients Most Worried About Finances Have Worse Outcomes

Roswell Park Comprehensive Cancer Center New research from Roswell Park Comprehensive Cancer Center provides the first evidence that a cancer patient’s level of financial worry as they begin treatment predicts how likely it is that their treatment will be successful. The study's senior author is Anurag Singh, MD. Read More

Abundance of Iron Drives Cell Death, Could Be Key to Novel Neuroblastoma Treatments

VCU Massey Comprehensive Cancer Center Anthony Faber, PhD, and a team of researchers at VCU Massey Cancer Center are studying how the gene MYCN and an abundance of iron can drive cancer cell death in neuroblastoma and potentially be targeted with novel treatments. Read More
Yoshida Honored for Increasing Colorectal Cancer Screenings

Yoshida Honored for Increasing Colorectal Cancer Screenings

University of Virginia Cancer Center Cynthia M. Yoshida, MD, is one of six winners of a national award recognizing health care providers and institutions for their work to increase colorectal cancer screening rates. Dr. Yoshida is medical lead of UVA Cancer Center’s Colorectal Cancer Screening Program. Read More

Study Incorporates Genetics, Smoking History to Identify High-Risk Smokers for Lung Cancer Screening

Vanderbilt-Ingram Cancer Center A study by Vanderbilt researchers that analyzed both smoking history and genetic risk variants for lung cancer supports modifying current guidelines to include additional smokers for lung cancer screening. Read More
Researchers Study Role of Zinc in Cancer

Researchers Study Role of Zinc in Cancer

Wilmot Cancer Institute, UR Medicine An essential mineral used to boost the immune system and block sunburns, zinc—in a different form—can also stabilize a protein that helps to prevent most cancers, according to a Wilmot Cancer Institute study led by Darren Carpizo, MD, PhD. Read More

Proteomics Analysis Identifies Potential Drug Targets for Aggressive Human Cancers

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine Historically, researchers have mostly generated transcriptomic data from cancer tissues, seeking clues about altered cellular pathways that might drive cancer behavior and represent novel therapeutic targets. While this approach has been useful, Baylor College of Medicine researchers think that transcriptomic data alone might not tell the whole story behind cancer. Read More
Community Outreach and Engagement Team Expands

Community Outreach and Engagement Team Expands

Duke Cancer Institute, Duke University Medical Center Tomi Akinyemiju, PhD, MS, has been named Duke Cancer Institute’s new associate director of community outreach and engagement. Before joining Duke in 2019 she was assistant dean for inclusive excellence at Markey Cancer Center at the University of Kentucky. Read More
Miaskowski Recognized as Champion of Supportive Care Science

Miaskowski Recognized as Champion of Supportive Care Science

UCSF Helen Diller Family Comprehensive Cancer Center In commemoration of the 50th Anniversary of the National Cancer Act, the National Cancer Institute's Division of Cancer Prevention honors Christine Miaskowski, RN, PhD, FAAN, as a champion and changemaker of cancer prevention, early detection, and symptom science. Read More

Carpten Elected Fellow of AACR Academy

USC Norris Comprehensive Cancer Center John D. Carpten, PhD, founding chair for the Department of Translational Genomics in the Keck School of Medicine of USC, has been named to the 2021 class of fellows of the American Association for Cancer Research’s AACR Academy. Read More

Stopping Mutant KRAS Could Enhance Therapies for Pancreatic Cancer

Stony Brook Cancer Center A collaborative study by Stony Brook University scientists takes an initial step toward better understanding how KRAS drives immune evasion and demonstrates a lowering of the KRAS activity resulting in a more favorable immune environment to fight cancer. Read More

Promising Role for Whole Genome Sequencing in Guiding Blood Cancer Treatment

Siteman Cancer Center Whole genome sequencing is a potentially viable approach for determining the best treatment regimen for individual patients with acute myeloid leukemia or myelodysplastic syndrome, according to a new study from Washington University researchers at Siteman Cancer Center. David H. Spencer, MD, PhD, is senior author of the study. Read More

Multisystem Failure Regarding Frailty Necessitates Multisystem Intervention

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Gaining a better understanding of physical frailty could eventually help people age more healthfully, suggests a Johns Hopkins research team led by Ravi Varadhan, PhD, and Linda Fried, MD, MPH. Read More

High Tumor Mutation Burden Predicts Immunotherapy Response in Some Cancers

The University of Texas MD Anderson Cancer Center A high rate of genetic mutations within a tumor, known as high tumor mutation burden, was only useful for predicting clinical responses to immune checkpoint inhibitors in a subset of cancer types, according to a new study led by researchers from The University of Texas MD Anderson Cancer Center. Read More

Fundamental Proteins That Guide Embryo Development Are Co-Opted by Cancer

Fred Hutchinson Cancer Center Fred Hutchinson Cancer Research Center scientists have identified a new protein that provides insights into a fundamental biological process and may also lead to new cancer treatments. A second study demonstrated that cancer co-opts these unusual proteins to further its growth and development. Read More

Fecal Transplant Boosts Cancer Immunotherapy

UPMC Hillman Cancer Center Researchers at UPMC Hillman Cancer Center and the National Cancer Institute demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy—which has a failure rate of 40 percent for this type of cancer—into patients who do. Read More
Hawley to Oversee Education Training Programs

Hawley to Oversee Education, Training Programs

University of Michigan Rogel Cancer Center The University of Michigan Rogel Cancer Center has named Sarah Hawley, PhD, MPH, associate director for training, education and career development. She will lead the center’s efforts to coordinate and enhance robust resources that support faculty, trainees, and students interested in cancer research. Read More
1 47 Million Awarded to Study DNA Damage Regulation

$1.47 Million Awarded to Study DNA Damage Regulation

UAMS Winthrop P. Rockefeller Cancer Institute A five-year, $1.47 million National Cancer Institute grant has been awarded to researcher Justin Leung, PhD, at the University of Arkansas for Medical Sciences (UAMS) to study DNA damage regulation. Dr. Leung’s project is a collaboration with Robert Eoff, PhD. Read More
Greco Named New Councilor for Association for Academic Surgery

Greco Named New Councilor for Association for Academic Surgery

Fox Chase Cancer Center, Temple Health Stephanie Greco, MD, assistant professor in the Department of Surgical Oncology at Fox Chase Cancer Center, was recently named a new councilor for the Association for Academic Surgery. Read More
Community Engagement in HIV Trials Guides Equity for COVID 19 Vaccine Studies

Community Engagement in HIV Trials Guides Equity for COVID-19 Vaccine Studies

Fred Hutchinson Cancer Center Last spring, as COVID-19 began to tear through American cities and was disproportionately affecting communities of color, a Fred Hutchinson Cancer Research Center scientist pivoted to the vital work of engaging these same communities in trials of coronavirus vaccines. Read More

New Biomarker of Response to Checkpoint Inhibitors Identified

Roswell Park Comprehensive Cancer Center A team of Roswell Park researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors shortly after patients with non-small cell lung cancer initiate therapy. Read More
Associate Director for Mentoring and Career Development Announced

Associate Director for Mentoring and Career Development Announced

Wilmot Cancer Institute, UR Medicine In January, breast oncologist Ruth O’Regan, MD, officially joined the University of Rochester Medical Center from the University of Wisconsin. Now she will have significant involvement with Wilmot Cancer Institute, serving as associate director for mentoring and career development. Read More
Hampel Named to Leadership Position for National Society of Genetic Counselors

Hampel Named to Leadership Position for National Society of Genetic Counselors

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Heather Hampel, MS, LGC, has been elected secretary/treasurer-elect for the National Society of Genetic Counselors (NSGC). Her two-year term began in January 2021. Founded in 1971, the NSGC is the only professional organization that promotes the professional interests of genetic counselors. Read More

Vital Player Identified in Graft-Versus-Host Disease and Organ Transplant Rejection

University of Michigan Rogel Cancer Center A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation, according to a new study by researchers at the University of Michigan Rogel Cancer Center and Michigan Medicine. Read More

Therapy Sneaks Into Hard Layer of Pancreatic Cancer Tumor, Destroys From Within

UC San Diego Moores Cancer Center Researchers at University of California San Diego School of Medicine and Moores Cancer Center, in collaboration with Sanford Burnham Prebys Medical Discovery Institute and Columbia University, have demonstrated that a new tumor-penetrating therapy, tested in animal models, may enhance the effects of chemotherapy, reduce metastasis, and increase survival. Read More

System of Excellence Recognition for Hidden Scar Breast Cancer Surgery

UK Markey Cancer Center UK HealthCare, home to the UK Markey Cancer Center, has officially been recognized as a System of Excellence for Hidden Scar breast cancer surgery, the highest level of Hidden Scar designation. Read More

New Leadership Appointments

Robert H. Lurie Comprehensive Cancer Center of Northwestern University The Lurie Cancer Center announces several new leadership appointments, effective April 1, 2021: Marcelo Bonini, PhD, associate director for education and training; Devalingam Mahalingam, MBBCh BAO, director of the clinical trials office; and Priya Kumthekar, MD, co-chair of the scientific review committee. Read More
Researcher Gets Early Career Award

Researcher Gets Early Career Award

University of New Mexico Comprehensive Cancer Center Ichiko Kinjyo, MD, PhD, was recently named a 2021 recipient of the Liz Tilberis Early Career Award. She was recognized for her work with Sarah Adams, MD, in exploring how a combination of a PARP-inhibitor and immunomodulation via immune checkpoint blockade can improve ovarian cancer treatment. Read More
Forty Three Percent of Melanoma Patients Have Chronic Complications From Immunotherapies

Forty-Three Percent of Melanoma Patients Have Chronic Complications From Immunotherapies

Vanderbilt-Ingram Cancer Center Chronic side effects among melanoma survivors after treatment with anti-PD-1 immunotherapies are more common than previously recognized, according to a new study. Senior author is Douglas Johnson, MD, MSCI, clinical director of melanoma at Vanderbilt-Ingram Cancer Center. Read More
Researchers Receive PCF Challenge Award

Researchers Receive PCF Challenge Award

Sidney Kimmel Cancer Center at Jefferson Health The Prostate Cancer Foundation (PCF) recently announced that a multi-institutional team led by Sidney Kimmel Cancer Center researcher Veda N. Giri, MD, has been awarded the 2020 Janssen-PCF Challenge Award. Read More
Write Your Representatives to Support the TREAT Act

Write Your Representatives to Support the TREAT Act

The Temporary Reciprocity to Ensure Access to Treatment (TREAT) Act (S. 168/H.R. 708) is a critical, bipartisan piece of legislation that will allow any licensed health care provider in good standing to render services—including telehealth visits—in all states for the duration of the COVID-19 pandemic. AACI is asking cancer centers to reach out to their congressional delegations to urge them to co-sponsor and support the TREAT Act with a customizable advocacy letter.   Read More
Nursing Team Honored With Achievement Award

Nursing Team Honored With Achievement Award

Fox Chase Cancer Center, Temple Health A nursing team at Fox Chase Cancer Center has been honored as a recipient of the 2021 I AM Patient Safety award from the Patient Safety Authority. The third floor surgical nursing team was recognized for reaching the significant milestone of one year with no patient falls on their three south unit. Read More
Associate Director for Cancer Equity Announced

Associate Director for Cancer Equity Announced

USC Norris Comprehensive Cancer Center Chanita Hughes-Halbert, PhD, will join USC Norris Comprehensive Cancer Center as associate director for cancer equity, a newly created position. Her appointment begins July 1 and she joins USC from the Medical University of South Carolina. Read More