Skip to main content

Search Results

Your search for "" returned 8200 results.

Researchers Identify Mechanism for Treating Cancer Cells

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center In a new study, investigators have determined that a chemotherapy drug called Azacytidine can cause certain cancer cells that do not have a BRCA mutation to respond very well to therapies that specifically target cells with these gene mutations. Read More

Largest-Ever Study of Prostate Cancer Genomics in Black Men IDs Potential Therapy Targets

UCSF Helen Diller Family Comprehensive Cancer Center In the largest study of its kind to date, researchers from Boston University School of Medicine, UC San Francisco, and Northwestern University have identified genes that are more frequently altered in prostate tumors from men of African ancestry compared to other racial groups, though the reasons for these differences are not known, the authors say.  Read More

Big Data Studies Uncover Disparities in Access, Improve Patient Outcomes

Case Comprehensive Cancer Center A new study by a team of investigators from the Case Comprehensive Cancer Center indicates the expansion of Medicaid led to earlier detection of cancer in individuals with low incomes. The findings suggest Medicaid expansion will have widespread meaningful health impact. Read More
Clevenger Named Associate Director for Precision Oncology

Clevenger Named Associate Director for Precision Oncology

VCU Massey Comprehensive Cancer Center Charles Clevenger, MD, PhD, has been named associate director for precision oncology at VCU Massey Cancer Center. His lab has made fundamental insights into novel mechanisms of prolactin receptor signal transduction and is translating these findings into clinical trials. Read More

$3.7 Million NCI Grant to Support Research Exploring Mysterious Link Between Cancer, HIV/AIDS

Case Comprehensive Cancer Center Ge Jin, PhD, and Bingcheng Wang, PhD, were recently awarded a five-year, $3.7 million grant from the National Cancer Institute (NCI) to explore why those living with HIV have a higher risk for certain kinds of cancers, such as lung cancer. Read More
Fox Chase Radiation Oncology Residency Program Accredited by ACGME

Fox Chase Radiation Oncology Residency Program Accredited by ACGME

Fox Chase Cancer Center, Temple Health The Radiation Oncology Residency Program at Fox Chase Cancer Center has received accreditation from the Accreditation Council for Graduate Medical Education (ACGME). Stephanie E. Weiss, MD, FASTRO, directs the program. Read More
Studies Highlight Emerging Treatment Options for Neuroendocrine Tumors

Studies Highlight Emerging Treatment Options for Neuroendocrine Tumors

Roswell Park Comprehensive Cancer Center Two new studies led by Renuka Iyer, MD, section chief for gastrointestinal oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors. Read More
Wiggins Honored With NAACCR Muir Award

Wiggins Honored With NAACCR Muir Award

University of New Mexico Comprehensive Cancer Center Chuck Wiggins, PhD, director of the New Mexico Tumor Registry, was recently honored by the North American Association of Central Cancer Registries with its Calum S. Muir Memorial Award. The award recognizes substantive and outstanding contributions to the field of cancer surveillance. Read More

Skin Cancer Growth Driven by Subset of Cellular Masterminds

Stanford Cancer Institute An elite population of cancer cells marshal at the leading edges of a growing skin tumor to guide its metastasis and help it evade the body’s immune system, researchers at the Stanford University School of Medicine, led by Paul Khavari, MD, PhD, have found. Read More
IU Physicians Purdue Scientists Collaborate to Develop Test to Detect Kidney Cancer

IU Physicians, Purdue Scientists Collaborate to Develop Test to Detect Kidney Cancer

Indiana University Melvin and Bren Simon Comprehensive Cancer Center Ronald S. Boris, MD, and cancer physician colleagues at Indiana University are working with scientists at Purdue University to develop a urine test that would enable patients to avoid an invasive, painful biopsy to detect a type of kidney cancer. Read More

Excellent Research Results for CAR T Therapy Against Hodgkin Lymphoma

UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill CAR T immunotherapy has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston. Read More

Breast Cancer Cells Can Reprogram Immune Cells to Assist in Metastasis

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Johns Hopkins Kimmel Cancer Center investigators report they have uncovered a new mechanism by which invasive breast cancer cells evade the immune system to metastasize to other areas of the body. They propose that therapies targeting this process could be developed to halt or prevent metastasis and reduce breast cancer deaths. Read More

A New Way to Target Cancers Using 'Synthetic Lethality'

UC San Diego Moores Cancer Center With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells. Synthetic lethality results when non-lethal mutations in different genes become deadly when combined in cells. Read More
Molecular and Cellular Oncogenesis Professor Appointed

Molecular and Cellular Oncogenesis Professor Appointed

Ellen and Ronald Caplan Cancer Center of The Wistar Institute Chengyu Liang, MD, PhD, has been appointed as professor in the Molecular & Cellular Oncogenesis Program of The Wistar Institute Cancer Center. The Liang laboratory is focused on the mechanisms that regulate fundamental cellular processes such as autophagy, cell death, DNA damage repair, and membrane trafficking in the context of cancer and infectious disease. Read More
Director Named for Center for Community Engagement and Health Equity

Director Named for Center for Community Engagement and Health Equity

Yale Cancer Center, Yale School of Medicine Marcella Nunez-Smith, MD, MHS, has been appointed director of the Center for Community Engagement and Health Equity for Yale Cancer Center (YCC) and Smilow Cancer Hospital (SCH), as well as chief health equity officer and deputy chief medical officer at SCH, and associate cancer center director for community outreach and engagement at YCC. Read More

Radiation Oncologists Named ASTRO Fellows

UPMC Hillman Cancer Center Two UPMC Hillman Cancer Center radiation oncologists have been designated Fellows of the American Society for Radiation Oncology (FASTRO), the world’s largest society for radiation oncology professionals. Felicia Snead, MD, and Sushil Beriwal, MD, MBA, will receive their FASTRO designation at a virtual awards ceremony on October 27, during ASTRO’s 62nd annual meeting. Read More
Study of Early Onset Colorectal Cancer in Young Men Reveals Hotspots of Death in U S

Study of Early-Onset Colorectal Cancer in Young Men Reveals Hotspots of Death in U.S.

Huntsman Cancer Institute at the University of Utah A study led by Charles R. Rogers, PhD, MPH, MS, and his colleagues, found that many new colorectal cancer diagnoses are occurring in counties in the lower Mississippi Delta, west-central Appalachia, and eastern Virginia/North Carolina. Read More

Probe Developed to Assess Prostate Cancer Aggressiveness

Cancer Center at Illinois Current prostate cancer diagnostics, such as the serum test and physical exam, work well for detection, but don’t accurately identify the stage or grade of the disease. To improve precision, Illinois researchers are developing a solution using an imaging probe that determines the aggressiveness of cancer cells. Read More

Microbiome Might Reveal Whether Immune Therapy Can Benefit a Patient

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute The intestinal microbiome might offer a window into whether cancer patients can benefit from immune therapy, according to a new study by researchers at OSUCCC – James. Read More

Study Provides New Insight on Colorectal Cancer Growth

UK Markey Cancer Center A new study by researchers at the University of Kentucky identifies a novel function of the enzyme spermine synthase (SMS) to facilitate colorectal cancer growth. SMS produces spermine from spermidine, which has been shown to be important for cell growth. However, excessive accumulation of spermidine can have harmful effects on cell viability. Read More

Boosting Immune Memory Improves Immunotherapy, Lowers Cancer Recurrence in Mice

UPMC Hillman Cancer Center Blocking a newly identified "immune memory checkpoint" in immune cells could improve immunotherapy and help prevent cancers from recurring, according to new findings in mice and human samples by researchers at the UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine. Read More
Hoimes Joins Duke Genitourinary Oncology

Hoimes Joins Duke Genitourinary Oncology

Duke Cancer Institute, Duke University Medical Center Christopher Hoimes, DO, PhD, has joined the genitourinary (GU) oncology program at Duke Cancer Institute where he will serve as clinical investigator with a focus on GU cancers, experimental therapeutics, and early phase trials. He was previously director of GU malignancies at the Case Comprehensive Cancer Center. Read More

Phosphoprotein Biomarkers to Guide Cancer Therapy Identified

O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham Researchers led by James Bibb, PhD, suggest using a broader lens of post-translational modification analysis to identify new biomarkers of cancer drivers that may allow a much more precise prediction of patient responses to treatments. Read More

New Data Offer Insights on COVID Treatments for People With Cancer

Vanderbilt-Ingram Cancer Center Newly released data on treatment outcomes of people with cancer diagnosed with COVID-19 reveal a racial disparity in access to Remdesivir, an antiviral drug that has been shown to shorten hospital stays, and increased mortality associated with dexamethasone, a steroid that has had the opposite effect in the general patient population. Read More

Study Suggests Method to Starve Pancreatic Cancer Cells

University of Michigan Rogel Cancer Center A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross-talk between cells that might be attacked with new therapies, starving the cancer cells of vital nutrients. Read More

Portable Device May Change Standard of Care for Skin Cancer

The University of Arizona Cancer Center Researchers at the University of Arizona Health Sciences have developed—and are continuing to improve—a handheld device to bring the next generation of skin cancer prevention and treatment options to more patients. Described as a "portable confocal microscope," the device is a modernized and more practical use of reflective confocal microscopy — technology that provides non-invasive imaging of the skin. Read More

Nationwide Trends Show Fewer Cancer Patients Seeking Care Since Start of Pandemic

Sidney Kimmel Cancer Center at Jefferson Health Research from the Sidney Kimmel Cancer Center at Jefferson Health found significant decreases nationwide in the number of patients being seen for cancer-related care as the COVID-19 pandemic progressed during the few first months of 2020. The most significant decline was seen in encounters related to new cancer incidences, which included screening, initial diagnosis, second opinion, and treatment initiation appointments. Read More

Gene Responsible for Deadly Glioblastoma Identified

University of Virginia Cancer Center Scientists have identified an oncogene responsible for glioblastoma. Researchers say the oncogene is essential to the survival of the cancer cells — without it, the cancer cells die. Scientists have already developed many targeted therapies for other cancers with a similar "oncogene addiction." Read More

UAMS Expands With Addition of 12 Oncologists

UAMS Winthrop P. Rockefeller Cancer Institute The addition of 12 oncologists will expand services and increase access for patients at the Winthrop P. Rockefeller Cancer Institute at the University of Arkansas for Medical Sciences. Six of these doctors will treat outpatients at clinics; the remaining six will serve as hospitalists for cancer patients. Read More
AACI Stands in Support of Dr Anthony Fauci Continued COVID 19 Guidance

AACI Stands in Support of Dr. Anthony Fauci, Continued COVID-19 Guidance

Last month AACI issued a press release affirming its strong support of Dr. Anthony Fauci in light of public criticism of his recommendations for stemming the spread of the novel coronavirus. In addition to issuing its own press release, AACI joined over 50 science and public health organizations to express support for Dr. Fauci in a letter to Vice President Mike Pence. Read More
Researchers Look to Cancer Studies to Understand Health Care Racial Disparities

Researchers Look to Cancer Studies to Understand Health Care Racial Disparities

Karmanos Cancer Institute, Wayne State University At Karmanos Cancer Institute, clinical and scientific researchers are examining factors that have led to the African-American population shouldering the heavy burden of cancer. The COVID-19 pandemic is providing a new lens through which cancer researchers can examine disparities in care. Hayley Thompson, PhD, is associate center director for community outreach and engagement. Read More
Researchers Help Identify Best Practices for Cancer Patient Care During COVID 19

Researchers Help Identify Best Practices for Cancer Patient Care During COVID-19

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center researchers were part of a national team that published a paper identifying best practices for protecting vulnerable cancer patients during the COVID-19 pandemic. "We’re dealing with lung cancer and our lung cancer patients may be more at risk for severe disease due to COVID-19. A lot of the management we do puts them at greater risk after that," said Sameera Kumar, MD, one of the authors on the paper. Read More

ABMT House Calls

Duke Cancer Institute, Duke University Medical Center Stem cell transplant patients are highly immune-compromised, so they are among the most vulnerable to COVID-19. That’s why, in early March 2020, as the COVID-19 epidemic ramped up, the Duke Adult Blood and Marrow Transplant program leadership team made home care the standard of care for all active hematopoietic stem cell transplant patients. Read More
Hwu Named President and CEO

Hwu Named President and CEO

Moffitt Cancer Center Tumor immunologist Patrick Hwu, MD, has been appointed the new president and CEO of Moffitt Cancer Center. He joins Moffitt from The University of Texas MD Anderson Cancer Center, where he is the division head of Cancer Medicine. Dr. Hwu begins his new role at Moffitt on November 10. Read More

NIH Awards $11.2 Million for Pharmaceutical Research and Innovation Center

UK Markey Cancer Center The University of Kentucky was recently awarded a Centers of Biomedical Research Excellence grant to study translational chemical biology from the National Institutes of General Medical Sciences, part of the National Institutes of Health. The $11.2 million grant will fund UK's Center of Biomedical Research Excellence in Pharmaceutical Research and Innovation. Read More
Wandinger Ness Receives PAESMEM

Wandinger-Ness Receives PAESMEM

University of New Mexico Comprehensive Cancer Center Angela Wandinger-Ness, PhD, received the 2020 Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM) in an online ceremony. She is the Victor and Ruby Hansen Surface Endowed Professor in Cancer Cell Biology and Clinical Translation at the UNM Comprehensive Cancer Center.  Read More
Mesa Elected Officer of Leukemia Lymphoma Society Board

Mesa Elected Officer of Leukemia & Lymphoma Society Board

Mays Cancer Center at UT Health San Antonio MD Anderson Ruben Mesa, MD, FACP, has been elected an officer on the national board of the Leukemia & Lymphoma Society. Dr. Mesa is director of the Mays Cancer Center, home to UT Health San Antonio MD Anderson, where he holds the Mays Family Foundation Distinguished University Presidential Chair. Read More

New Repository Program Accepts Oral Cancer Drug Donations to Help Patients in Need

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Patients are now able to donate no-longer-needed oral cancer therapy drugs for the benefit of other cancer patients through new state rules spearheaded by the State of Ohio Board of Pharmacy and OSUCCC – James. Read More
10 6 Million Grant to Expand National Proteomics Resource

$10.6 Million Grant to Expand National Proteomics Resource

UAMS Winthrop P. Rockefeller Cancer Institute A $10.6 million grant from the National Institutes of Health, awarded to Alan Tackett, PhD, will allow the University of Arkansas for Medical Sciences to greatly expand its proteomics resource. The grant will establish the IDeA National Resource for Quantitative Proteomics. Read More

$5.5 Million Grant Received to Study Health Impact of Youth Vaping

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute Researchers at Ohio State will study the health effects of e-cigarettes and nicotine on youth and help develop vaping cessation programs after receiving a $5.5 million grant from the American Heart Association, which has distributed nearly $17 million in grants as part of its End Nicotine Addiction in Children and Teens research initiative. Read More

Study Suggests New Approach to Improve Radiation Therapy Resistance in Glioblastoma

University of Michigan Rogel Cancer Center Many modern cancer drugs target a specific genetic mutation that is driving a particular cancer’s runaway growth and division, but this strategy hasn’t worked well against glioblastoma. Now research led by the University of Michigan Rogel Cancer Center has hit upon a new approach: make radiation therapy more effective for glioblastoma patients by targeting a critical metabolic pathway and disrupting its ability to repair the DNA damage caused by…
Massey Scientists Join International Effort to Streamline Brain Metastasis Research

Massey Scientists Join International Effort to Streamline Brain Metastasis Research

VCU Massey Comprehensive Cancer Center The laboratory of Paula D. Bos, PhD, has joined forces with 18 other international laboratories to develop the first collaborative platform to streamline research into brain metastases. The effort, called the Brain Metastasis Cell Lines Panel, has already compiled more than 60 different cell lines related to brain metastasis research. Read More
O Malley Returns to Leadership Role

O'Malley Returns to Leadership Role

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Bert W. O’Malley, Jr., MD, has been appointed as the new president and chief executive officer of the University of Maryland Medical Center. Dr. O'Malley served in multiple University of Maryland leadership roles from 1999 - 2003 including associate director of the University of Maryland Greenebaum Comprehensive Cancer Center. Read More
Grossman Named Cancer Physician in Chief

Grossman Named Cancer Physician-in-Chief

USC Norris Comprehensive Cancer Center Keck Medicine of USC has named oncologist and cancer researcher Steven Grossman, MD, PhD, as USC Norris Comprehensive Cancer Center’s cancer physician-in-chief. He will step into the role on September 15. Read More

Targeting Ultrasound at the Brain for Noninvasive Brain Cancer Diagnosis

Siteman Cancer Center Researchers at Washington University in St. Louis, led by Hong Chen, PhD, are developing a new way to diagnose brain tumors without any incisions. The method uses ultrasonic energy to target tumors deep in the brain. Read More
Executive Medical Director Named for VICC Cancer Patient Care Center

Executive Medical Director Named for VICC Cancer Patient Care Center

Vanderbilt-Ingram Cancer Center Laura Goff, MD, MSCI, has been named the executive medical director of the Vanderbilt-Ingram Cancer Center Cancer Patient Care Center. She will oversee the cancer clinical enterprise in Nashville, including the flagship Henry-Joyce Cancer Clinic, among other responsibilities. Read More

Serology Test May Not Detect Antibodies That Could Confirm Protection Against COVID-19 Reinfection

The University of Texas MD Anderson Cancer Center Two types of detectable antibody responses in SARS-CoV-2 (COVID-19) tell very different stories and may indicate ways to enhance public health efforts against the disease, according to researchers at The University of Texas MD Anderson Cancer Center. Antibodies to the SARS-CoV-2 spike protein receptor binding domain might neutralize virus infection, while the SARS-CoV-2 nucleocapsid protein antibody may often only indicate exposure to the…
Huerta Heads Cancer Prevention and Education Program

Huerta Heads Cancer Prevention and Education Program

GW Cancer Center Elmer E. Huerta, MD, MPH, will serve as the director of the Cancer Preventorium at GW Cancer Center and as professor of medicine at the GW School of Medicine and Health Sciences.  Read More
Systematic Testing of Environmental Surfaces in a Radiation Oncology Clinic Shows No Detectable SARS Co V2

Systematic Testing of Environmental Surfaces in a Radiation Oncology Clinic Shows No Detectable SARS-CoV2

Rutgers Cancer Institute of New Jersey A Rutgers Cancer Institute of New Jersey study shows environmental surface testing at the center’s radiation oncology department, during the height of the COVID-19 pandemic in the state, showed no detectable SARS-CoV2. The work was led by Imraan Jan, DO (pictured), and Bruce G. Haffty, MD. Read More

Scientists Look to Common Herb to Stem Progression of Early-Stage Breast Cancer

The University of Kansas Cancer Center Rosemary, a fragrant herb, may contain properties that prevent breast cancer from progressing. Researchers at The University of Kansas Cancer Center, led by Fariba Behbod, PharmD, PhD, recently received funding to study this natural compound as a chemoprevention agent for women diagnosed with early-stage breast cancer. Read More

Link Found Between Gut Microbiome, Cancer Treatment Outcomes

City of Hope Comprehensive Cancer Center City of Hope physicians, working with scientists at Translational Genomics Research Institute, have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens. Read More

HDAC6 Can Control Tumor Growth and Halt Metastasis in Triple-Negative Breast Cancer

GW Cancer Center Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study by investigators at GW Cancer Center. Read More
Brenner Chairs Department Focused on Diabetes and Cancer Metabolism

Brenner Chairs Department Focused on Diabetes and Cancer Metabolism

City of Hope Comprehensive Cancer Center Biochemist Charles Brenner, PhD, has joined City of Hope to lead the nation’s first research department focused on the intersection between cancer and diabetes. He is also the inaugural holder of the Alfred E Mann Family Foundation Chair in Diabetes and Cancer Metabolism. Read More

$3 Million Grant to Help Develop Early Detection Liver Cancer Test

UCLA Jonsson Comprehensive Cancer Center Researchers from the UCLA Jonsson Comprehensive Cancer Center were awarded a $2.97 million grant from the National Cancer Institute to develop a nanotechnology-enabled cancer diagnostic solution that will help detect early stage liver cancer for people who are at risk of developing the disease. This is the second grant of a similar scale awarded to this joint research team in 2020. Read More
Merad Elected to National Academy of Science

Merad Elected to National Academy of Science

The Tisch Cancer Institute at Mount Sinai Miriam Merad, MD, PhD, was elected to the National Academy of Science in recognition of her transformational contributions to the fields of myeloid cell biology and innate immunity. Dr. Merad is the Mount Sinai Professor in Cancer Immunology and director of the Precision Immunology Institute. Read More
New Models to Accelerate Progress in Preventing Drug Resistance in Lung Pancreas Cancers

New Models to Accelerate Progress in Preventing Drug Resistance in Lung, Pancreas Cancers

Huntsman Cancer Institute at the University of Utah Scientists at Huntsman Cancer Institute at the University of Utah have developed new models to study molecular characteristics of tumors of the lung and pancreas that are driven by mutations in a gene named NTRK1. The study was led by Martin McMahon, PhD, and Aria Vaishnavi, PhD. Read More

Differing Immune-Cell Subsets Underlie Sex Disparities in Glioblastoma

Case Comprehensive Cancer Center A recent article highlights disparities in immune system functions between male and female glioblastoma patients that may underlie some of the observed sex differences in cancer incidence, prognosis, and treatment response. Researchers found that monocytic myeloid-derived suppressor cells were enriched in the tumors of male mice, but not female mice. Read More
Kuhs Named Co Leader of Markey Cancer Prevention Control Research Program

Kuhs Named Co-Leader of Markey Cancer Prevention & Control Research Program

UK Markey Cancer Center UK Markey Cancer Center has announced that Krystle Kuhs, PhD, MPH, will serve as co-leader of its Cancer Prevention and Control Research Program. She will co-lead the program with Jerod Stapleton, PhD, who joined the university in 2019. Read More
Jung Named Chair of Cancer Biology

Jung Named Chair of Cancer Biology

Case Comprehensive Cancer Center Jae Jung, PhD, has been appointed chair of Lerner Research Institute's Department of Cancer Biology where he will lead the department’s work in understanding the biological underpinnings of cancer. He will also serve as director of the Cleveland Clinic's new Center for Global and Emerging Pathogens Research. Read More

Link Found Between Minimally Invasive Procedure for Oropharyngeal Cancer and Longer Survival

Cedars-Sinai Cancer Robotic surgery for patients with early stage, oropharyngeal squamous cell cancer is associated with improved health outcomes, including better long-term survival, according to a Cedars-Sinai study. Read More
UF Named New Member of Pediatric Brain Tumor Consortium

UF Named New Member of Pediatric Brain Tumor Consortium

University of Florida Health Cancer Center When Sridharan Gururangan, FRCP, joined the University of Florida in 2016, he had a big goal for the university: to become a member of the Pediatric Brain Tumor Consortium (PBTC). In July, UF was named one of four new PBTC member institutions. Read More

Proposed Guidelines for Lung Cancer Screening Would Nearly Double Number of People Who Should Get Tested

Stanford Cancer Institute A new draft recommendation by a national panel of health care experts would nearly double the number of Americans eligible for lung cancer screenings — and should result in more women and African Americans getting screened. Read More

Immunotherapy-Resistant Cancers Eliminated in Mouse Study

Siteman Cancer Center The effects of a standard immunotherapy drug can be enhanced by blocking the protein TREM2, resulting in complete elimination of tumors, according to a study in mice by Washington University researchers at Siteman Cancer Center. Read More

Delaying Antiviral Treatment May Boost Immunity in Stem Cell Transplant Recipients

Roswell Park Comprehensive Cancer Center Patients who develop cytomegalovirus infections after allogeneic stem cell transplantation may be able to develop an immunity against the virus, strengthen their immune system, and reduce reliance on strong antiviral medications, a team of cellular-therapy specialists from Roswell Park Comprehensive Cancer Center has found. Read More

Breast Cancer Cells Use Message-Carrying Vesicles to Send Oncogenic Stimuli to Neighboring Normal Cells

Ellen and Ronald Caplan Cancer Center of The Wistar Institute According to a study led by Dario C. Altieri, MD, president and CEO of The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells. These messages are packaged into particles called extracellular vesicles and reprogram mitochondrial shape and position within the recipient normal cells to ultimately promote deregulated tissue morphogenesis. …
New Chief of Pediatric Hematology Oncology Stem Cell Transplantation Appointed

New Chief of Pediatric Hematology, Oncology, Stem Cell Transplantation Appointed

Stanford Cancer Institute Tanja Gruber, MD, PhD, has been appointed division chief of Hematology, Oncology, and Stem Cell Transplantation and Regenerative Medicine in the Division of Pediatrics at the Stanford University School of Medicine, associate director for childhood cancer in the Stanford Cancer Institute, and director of the Bass Center for Childhood Cancer and Blood Diseases at Stanford Children’s Health. Read More

$2.3 Million Grant Funds New Viral-Based Gene Therapies for Lung Cancer

VCU Massey Comprehensive Cancer Center Mutations in the p53 gene are found in more than half of all cancers, yet it has proven to be very difficult to target the gene with therapeutic drugs. VCU Massey Cancer Center researchers are hoping to turn the tide with an innovative viral-based strategy, and they recently received more than $2 million from the National Cancer Institute to fund their work.   Read More

Tobacco Flavor Ban Proposals in Kansas City

Developing a Blood Test for Breast Cancer

Developing a Blood Test for Breast Cancer

University of New Mexico Comprehensive Cancer Center Mammograms help to catch breast cancer in its early stages, but Dario Marchetti, PhD, thinks they can’t find it soon enough. He and his team are developing tools to find cancer cells in the blood, before the primary tumor grows large enough to see on a mammogram, and before tumors can grow in other parts of the body. Read More
Haring Joins National COVID 19 Native Expert Panel

Haring Joins National COVID-19 Native Expert Panel

Roswell Park Comprehensive Cancer Center Roswell Park's Rodney Haring, PhD, MSW, has been named to the COVID-19 Prevention Network Native Expert Panel, formed by the National Institute of Allergy and Infectious Disease. Read More
Targeted Therapy Combination Effective for Patients With Advanced Cholangiocarcinoma and BRAF Mutations

Targeted Therapy Combination Effective for Patients With Advanced Cholangiocarcinoma and BRAF Mutations

The University of Texas MD Anderson Cancer Center In a Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, the combination of dabrafenib, a BRAF inhibitor, and trametinib, a MEK inhibitor, achieved a 51 percent overall response rate in patients with cholangiocarcinoma marked by the BRAF V600E mutation. Vivek Subbiah, MD, is the study's lead author. Read More

Small Change Makes Cancer Vaccine More Effective in Animal Tests

Sidney Kimmel Cancer Center at Jefferson Health Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective. The change makes the vaccine less prone to being cleared by the immune system before it can generate immunity against the tumor components. The preclinical studies pave the way for a Phase II clinical trial opening to patients this fall. Read…

Acidic Niche Keeps Lymphatic System in Check During Immune Response, Researchers Say

Moffitt Cancer Center Moffitt Cancer Center researchers have described a novel acidic niche within lymph nodes that plays an integral role in regulating T cell activation. Their findings demonstrate the potential role for the lymph node microenvironment in shaping T cell biology. Read More
Senior Director of Population Sciences Named

Senior Director of Population Sciences Named

Huntsman Cancer Institute at the University of Utah Tracy Onega, PhD, has been appointed senior director of population sciences at Huntsman Cancer Institute (HCI) and professor of population sciences at the University of Utah. She began her service at HCI on August 1. Read More

Trial of Drug to Fight COVID-19 Launched

The University of Kansas Cancer Center The University of Kansas Medical Center has announced a trial exploring a drug intended to fight the cytokine storm common in COVID-19. The trial involved a unique partnership between a researcher usually focused on cancer and a researcher usually focused on cystic fibrosis. Read More

Fred Hutch Joins International COVID-19 Vaccine Effort

Fred Hutchinson Cancer Center Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network, funded by the National Institute of Allergy and Infectious Diseases. A team headquartered at Fred Hutch will lead operations across a network of at least five large-scale efficacy trials with over 100 clinical trial sites in the U.S. and abroad. Read More

Fox Chase in Partnership to Develop COVID Testing Swab

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center has formed a partnership with plastic injection molding company The Rodon Group to develop nasal and oral collection swabs to test for COVID-19. This partnership will provide Temple University Health System with necessary COVID-19 swabs for the next five years. Read More
Davis Named Senior Medical Director for Cancer Care Network and Strategy

Davis Named Senior Medical Director for Cancer Care Network and Strategy

Vanderbilt-Ingram Cancer Center Nancy Davis, MD, has been named senior medical director for VICC Cancer Care Network and Strategy, a new leadership position at Vanderbilt-Ingram Cancer Center responsible for expanding cancer clinics within and beyond the Middle Tennessee catchment area. Read More

Fox Chase Earns HAP Achievement Award

Fox Chase Cancer Center, Temple Health Fox Chase Cancer Center earned the Achievement Award from The Hospital and Healthsystem Association of Pennsylvania (HAP) for its outstanding effort to improve health care in the communities it serves. Fox Chase’s entry, "Nasogastric Tube Feeding for Radiation-Induced Dysphagia in Patients with Head and Neck Cancer," was chosen as an Excellence in Care award winner. Read More
Phil and Penny Knight to Receive AACI Champion for Cures Award

Phil and Penny Knight to Receive AACI Champion for Cures Award

Phil and Penny Knight will receive the 2020 AACI Champion for Cures Award, in recognition of their transformational philanthropy that advances our shared vision of a future without cancer. Brian Druker, MD, director of OHSU Knight Cancer Institute, will virtually present the award to the Nike, Inc. co-founder and his wife on Monday, October 12, during the 2020 AACI/CCAF Annual Meeting. Read More
Leveraging Prostate Cancer Research Against COVID 19

Leveraging Prostate Cancer Research Against COVID-19

University of Michigan Rogel Cancer Center What is the connection between COVID-19 and cancer? Arul Chinnaiyan, MD, PhD, has focused his entire career on cancer, identifying a protein that plays a key role in the development of prostate cancer in 2005. It turns out that same protein may also factor into how coronaviruses replicate. Read More
Researcher to Study Cellular Stress Responses Common in Cancer Aging

Researcher to Study Cellular Stress Responses Common in Cancer, Aging

The University of Arizona Cancer Center Understanding how cells respond to stress may provide new building blocks for designing future cancer and aging treatments, and University of Arizona Health Sciences researcher Timothy Bolger, PhD, has received a five-year, $1.6 million grant from the National Institute of General Medical Sciences to further study these implications. Read More
Annual Meeting Sessions Address Disparities in Cancer Care

Annual Meeting Sessions Address Disparities in Cancer Care

The 2020 AACI/CCAF Annual Meeting will virtually convene AACI cancer center members with national cancer research and advocacy groups, industry, and government health agencies on October 12-13. Two sessions at this year's meeting will address disparities in cancer care, including the disproportionate cancer burden experienced by people of color and the challenges of delivering cancer care in rural communities. Read More
Osborne Steps Down as Director

Osborne Steps Down as Director

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine After 15 years in the role, C. Kent Osborne, MD, has stepped down as director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine. He will stay on at Baylor as founding director of the center. Helen Heslop, MD, DSc (Hon), director of the Center for Cell and Gene Therapy, will serve as interim director. Read More
Sylvester Receives Landmark 126 Million Gift

Sylvester Receives Landmark $126 Million Gift

Sylvester Comprehensive Cancer Center, University of Miami A landmark gift of $126 million to the Sylvester Comprehensive Cancer Center at the University of Miami Leonard M. Miller School of Medicine will accelerate advances in finding cures for cancer and expand treatment options for patients. The anonymous donation, made in honor of Sylvester Director Stephen D. Nimer, MD, is the largest in the University of Miami’s 95-year history. Read More
Winn Part of AACR Congressional Briefing on Cancer Disparities

Winn Part of AACR Congressional Briefing on Cancer Disparities

VCU Massey Comprehensive Cancer Center As a member of the steering committee that contributed to the American Association of Cancer Research’s inaugural "Cancer Disparities Progress Report," VCU Massey Cancer Center Director Robert Winn, MD, recently participated in a virtual congressional briefing on the report’s findings. Read More

New Initiative Aims to Put Postponed Cancer Screenings 'Back on the Books'

Prevent Cancer Foundation To help encourage routine cancer screenings, especially as patients have postponed or canceled them during the COVID-19 pandemic, the Prevent Cancer Foundation has launched a public service announcement campaign, "Back on the Books," to remind people to reschedule their appointments.  Read More
KRAS Inhibitor Sotorasib Appears Safe Achieves Durable Clinical Benefit in Early Trial

KRAS Inhibitor Sotorasib Appears Safe, Achieves Durable Clinical Benefit in Early Trial

The University of Texas MD Anderson Cancer Center In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRAS G12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefits. David S. Hong, MD, is lead author on the study. Read More
Gruber to Head Center for Precision Medicine

Gruber to Head Center for Precision Medicine

City of Hope Comprehensive Cancer Center Cancer geneticist Stephen Gruber, MD, PhD, MPH, has joined City of Hope as the director of its newly founded Center for Precision Medicine. He will lead a team of more than 14 researchers who will work across the institution to pioneer personalized cancer prevention and treatment plans. Read More
111 Million NIH Grant Awarded to Prevent and Treat HIV Associated Cancers

$111 Million NIH Grant Awarded to Prevent and Treat HIV-Associated Cancers

Montefiore Einstein Comprehensive Cancer Center For 25 years, the AIDS Malignancy Consortium has led national and international efforts to prevent and treat of HIV-related cancers. Now, Montefiore Health System and Albert Einstein College of Medicine have received a five-year, $111 million grant from the National Cancer Institute to lead this research consortium. Joseph Sparano, MD, is principal investigator on the grant. Read More

Senate Bill 1864: Providing Coverage for Medicaid Beneficiaries

Clinical Trials Coverage for Medicaid Beneficiaries

City of Hope, Chimeric to Develop CAR T Cell Therapy

City of Hope Comprehensive Cancer Center City of Hope has licensed intellectual property relating to its pioneering chlorotoxin chimeric antigen receptor T cell therapy to Chimeric Therapeutics Limited, an Australian biotechnology company. The center has also dosed its first patient in its innovative chlorotoxin CAR T cell therapy trial. Read More

Two Million Americans Buy Prescription Drugs Outside the Country

University of Florida Health Cancer Center Buying prescription drugs from other countries is one way some Americans have coped with rising drug prices. A new University of Florida study finds that 1.5 percent of adults, or more than two million Americans, purchase their prescription drugs from outside the U.S. to save money. Read More
Tisch Gets Second Consecutive NCI Designation

Tisch Gets Second Consecutive NCI Designation

The Tisch Cancer Institute at Mount Sinai The Tisch Cancer Institute at Mount Sinai has been awarded $13 million as part of the renewal of its National Cancer Institute cancer center designation. The funding complements $53 million in current cancer research grants. Ramon Parsons, MD, PhD, is the center's director. Read More

Effort to Combat Melanoma Gets $13 Million Boost

UCLA Jonsson Comprehensive Cancer Center UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies. Read More

NIH Funds Research on Differences in Glioblastoma Between Males, Females

Case Comprehensive Cancer Center A Case Comprehensive Cancer Center-led team has secured $10.4 million over five years from the National Institutes of Health/National Cancer Institute to explore at the molecular level the differences in glioblastoma between males and females. Read More